An ultrasonic vaporization assembly includes: a piezoelectric drive element provided with a first through hole; a vaporizer plate stacked with the piezoelectric drive element, the vaporizer plate having a microporous zone at a position corresponding to the first through hole; and a loading board arranged on a side surface of the vaporizer plate which faces away from the piezoelectric drive element, the loading board being provided with a second through hole at a position corresponding to the microporous zone. A ratio of a pore size of the second through hole to a diameter of the microporous zone is greater than or equal to 0.75 and less than or equal to 1.5.

Disclosed herein is an implantable blood pump assembly that includes a housing defining an inlet, an outlet, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path. The blood pump assembly further includes a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet, a stator positioned within the internal compartment and operable to drive the rotor, and an inlet conduit connected to the housing inlet and having a downstream end that has a reduced cross-sectional area that produces a localized region of high velocity blood flow. The blood pump assembly further includes at least one pressure sensor positioned between the inlet and the outlet and configured to detect a pressure of blood flowing through the flow path. The pressure sensor is located adjacent the downstream end of the inlet conduit.

Devices and systems with methods for detecting a sealing condition between a patient interface and a patient, and adjusting the patient interface to maintain the patient interface in sealing contact with the patient. The patient interface may include a sealing structure to form a seal on the patient, and a positioning structure to secure the sealing structure to the patient. The patient interface may include a sensor coupled to the sealing structure. A processor determines the sealing condition between the sealing structure and the patient based on a signal from the sensor, and adjusts at least one of the sealing structure and the positioning structure to maintain the sealing structure in sealing contact with the patient. A prediction system predicts a leak between the sealing structure and the patient based on the sensor signal. A learning system learns how to fit the sealing structure to the patient to form a seal.

A medical device is provided with an alarm organization. A process for alarm organization of a medical device is also provided. Based on pressure measured values (99) and flow measured values (97) and with a comparison criterion it is determined whether an elevation of an airway pressure (105) of an anesthesia device or of a ventilator is caused by a coughing event. A visual and/or acoustic output (117, 121) of a warning or alarm (42) is adapted, indicating the elevated airway pressure P.sub.AW.sub._.sub.High (105).

Disclosed herein is an endotracheal tube cuff having a first layer, a second layer, and one or more sensors in a space between the first and second layers. The one or more sensors are operable to measure pressure between the endotracheal tube cuff and a tracheal wall of a patient. Also disclosed herein are methods of detecting a leak and preventing ischemia using the endotracheal tube cuff.

The present invention relates to a device and a method for alternately measuring the thoracic and pleural pressure and for gastropharyngeal or tracheal sealing, wherein the balloon component of a tube or catheter placed in the trachea or oesophagus alternates between two filling or functional states, wherein the filling state of the balloon component in the measuring mode assumes a value of constant, defined volume during the measurement, said value corresponding to a flaccid filling state, and the filling state of the balloon in the oesophageally or tracheally sealing functional mode maintains a constant, sealing pressure specified by the user. The controller device connected to the tube unit or catheter unit ensures rapid displacement of filling medium into and out of the tube balloon or catheter balloon in the state of tracheal or oesophageal sealing, wherein the tracheally or oesophageally sealing target pressure is maintained continuously by compensating pressure fluctuations in the balloon caused by respiratory mechanics by a continuous, compensating displacement of filling volume. The user can switch between the two functional states by means of a manual switchover function or by means of a programmable, chronological cycle. In addition to the possibility of an intermittent monitoring of the respiratory mechanics and a continuous, tracheally or oesophageally sealing balloon tamponade, the balloon placed in the trachea or oesophagus allows, in both functional states, the thoracic derivation of a triggering, respiratory-mechanical signal which can trigger a ventilating stroke assisting the patient in a ventilator connected to the device. The invention also describes structural and functional options for the simultaneous derivation of a neural and/or muscular electrical signal from the diaphragm of the patient and a respiratory-mechanical signal on the basis of thoracic or pleural pressure fluctuations derived tracheally or oesophageally.

A microporous vaporization assembly includes: a microporous vaporization plate for vaporizing an aerosol-generation substrate to generate aerosols; and a circuit board flexibly electrically connected to the microporous vaporization plate, the circuit board transmitting an electrical signal of the circuit board to the microporous vaporization plate. In an embodiment, the microporous vaporization assembly includes a flexible electrical conductor between the circuit board and the microporous vaporization plate. The flexible electrical conductor is in contact with the circuit board and the microporous vaporization plate respectively, to implement a flexible electrical connection between the circuit board and the microporous vaporization plate.

One aspect relates to a guidewire system, a measuring system, and a method for manufacturing such guidewire system. The guidewire system includes a guidewire and a surface acoustic wave sensor device. A portion of a surface of the guidewire is coated by the surface acoustic wave sensor device. The surface acoustic wave sensor device may be configured for measuring a pressure change. The surface acoustic wave sensor device includes a piezoelectric substrate and a transducer. A thickness of the surface acoustic wave sensor device perpendicular to a longitudinal direction of the guidewire is smaller than 100 μm.

The present invention provides a capsule for fluid sampling and drug delivery including: an enclosure; a sampling/drug delivery assembly, including a storage chamber arranged in the enclosure, a first one-way element and a second one-way element communicating with outside of the capsule and the storage chamber, and a pump changing pressure in the storage chamber, wherein the first one-way element and the second one-way element have same direction of access; and a control module, including a microprocessor in communication with the pump. The capsule can realize multiple times of sampling and drug delivery by means of control flow direction of sample or drug through the first one-way element and the second one-way element, and by changing the pressure of the storage chamber through the pump.

Numerous aspects of communication devices, methods, and systems are described in this application. One aspect is an apparatus comprising an energy generator comprising: a plurality of generator elements operable to output a plurality of different energy types in a signal direction toward a physiologic tissue; a printed circuit board that mechanically supports and electrically connects the plurality of generator elements to each other; each generator element of the plurality of generator elements being independently operable, when the energy generator is positioned relative to the physiologic tissue, to communicate with different nerves associated with the physiologic tissue by outputting a different portion of an energy signal in the signal direction toward the physiologic tissue with one energy type of the plurality of different energy types.