Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include eyeglasses, a photodiode positioned to detect ambient light, light sources, and an input device. The system can include a neural stimulation system that retrieves a profile and selects a light pattern having a fixed parameter and a variable parameter. The neural stimulation system can set a value of the variable parameter of the light pattern, construct an output signal, and then provide the output signal to the light sources to direct light towards the fovea.

To provide a brain wave and cell activity control device and method based on light stimulation in which light having a specific wavelength, such as violet light, is irradiated using continuous light or a specific blinking frequency, and a device for improvement, prevention, or increase in brain function. The above-described problem is solved by a brain wave and cell activity control device, based on light stimulation, that controls brain waves or cell activity by irradiating light having a specific wavelength onto a subject using continuous light or a specific blinking frequency. The brain wave and cell activity control device comprises a light source that irradiates the light having a specific wavelength using continuous light or a specific blinking frequency, and a control unit that controls an emission of light that induces specific brain waves, the brain waves of the subject having received the light being the same or substantially the same as, or different from a frequency of the light in an irradiation state. At this time, the light is preferably violet light, and the irradiation state of the light is preferably continuous light or a blinking frequency greater than 0 Hz and less than or equal to 150 Hz.

A handheld device for delivering therapeutic light toward an eye of a patient includes a device housing that is configured to be held by a user in delivering the therapeutic light, a plurality of light sources disposed within the device housing, and an array of lenses disposed near the distal end of the device housing. Each light source is configured to independently emit a beam of therapeutic light and each lens of the array is aligned with a respective light source so that each beam of therapeutic light that is emitted from the respective light sources is focused and directed by the respective lenses of the array to target tissue of the eye in order to therapeutically treat to the target tissue.

An illumination system adapted for an eyewear that includes a light source configured to emit a first light including a power spectrum having full width at half maximum of less than 100 nm in a first range of wavelengths and a second light including a power spectrum having full width at half maximum of less than 100 nm in a second range of wavelengths, the power spectrum of the first light and the power spectrum of the second light differ from each other, and the light source is further configured to emit pulses of light with a pre-determined time function. The pre-determined time function comprises a plurality of packets, each packet of the plurality of packets being followed by a packet interval, and each packet including a pulse alternation between a pulse of the first light and a pulse of the second light.

Provided is a region division method for laser treatment, and a laser treatment method and apparatus using the same. The region division method for laser treatment according to the present invention divides an area of an object to be treated by laser irradiation into a plurality of treatment regions and includes constructing a three-dimensional image of the object; using the three-dimensional image to obtain a normal vector for each of a plurality of points located on a surface of the object; dividing the points on the surface of the object into one or more groups based on a similarity between the obtained normal vectors; and generating a closed curve including at least some of points grouped into the same group to set a treatment region.

A pet care device may include a removable or swappable care tool mounted on a head. The head may include a sterilizer and a sensor to determine what kind of care tool is mounted. A controller may identify the type of care tool mounted on the head based on a sensing value of the sensor and control the sterilizer based on the identified care tool.

Respiratory function can be preserved in patients requiring mechanical ventilation (MV), such as patients with severe COVID-19, using a photoceutical applied by a photoceutical medical device (including at least one super pulsed laser to provide superpulsed light of a first wavelength, at least two non-coherent light sources to provide light of a second wavelength, and at least two other non-coherent light sources to provide light of a third wavelength) to at least one inspiratory muscle. The photoceutical includes a combination of superpulsed light of the first wavelength, light of the second wavelength, and light of the third wavelength. At least two sites on the body of the patient can be selected and the photoceutical can be delivered: at one of the sites for a first time period; and at another of the sites for a second time period.

A method for optogenetics experiments, based on wavefront shaping and including: calculating the transmission matrix between an input end and an output end of the multimode fiber under a fixed shape; implanting the output end into an intracranial space of an experimental subject; and performing wavefront compensation to a light to be input into the input end, according to the spatial position of the optical stimulation and the transmission matrix of the multimode fiber, to form a compensated expanded light, and inputting the compensated expanded light from the input end into the multimode fiber, such that the compensated expanded light, after being transmitted by the multimode fiber to the output end and output from the output end, is capable of focusing at the spatial position of the optical stimulation.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

The present invention is directed to a system and method for photoeradication of microorganisms from a target. The target is irradiated with pulsed purple or blue light in which (a) the light pulses have a peak irradiance and a pulse duration sufficient to optically excite a photoactive molecule capable of photoeradication of the microorganisms and (b) the light pulses are separated by an off time sufficient to allow the photoactive molecule to return to a ground state creating an oxidation reaction that produces free radicals which destroy a cellular structure of the microorganisms and thereby photoeradicate all or a portion of the microorganisms. The photoactive molecule may comprise either an endogenous molecule present in the microorganisms or an exogenous molecule applied to the target.