A system for imaging and examination of a cervix, comprising a control module connectable with a changeable head configured to image the cervix and collect a tissue biopsy, the head selected from a group consisting of a digital colposcope module, a transvaginal optical probe module and an endo-cervical endoscope module. The system may additionally comprise light source(s) to illuminate cervix tissue; sensing device(s) to generate signal(s) from light and/or to acquire image(s) of a portion of a cervix; and processor(s) in communication with the sensing device(s). The system is configured to: (i) analyze the signal(s); (ii) detect the size of the cervix; (iii) determine parameters defining properties of the cervix; (iv) determine and distinguish normal tissue from abnormal tissue within the cervix; (v) determine the location of area(s) of abnormal tissue in the cervix; and (vi) generate a panoramic view of the cervix.

The subject matter discloses a multi-sensor endoscope having a dynamic field of view comprising an elongated shaft terminating with a tip section; a maneuvering section connected to the elongated shaft; at least two sensors, wherein at least one sensor is placed behind the tip section, on the maneuvering section; and one or more illuminators located on external surface of the shaft. In some cases, the sensors include a camera. The subject matter also discloses a multi-sensor endoscopy system comprising an endoscope comprising a handle and a controller, such that the maneuvering section is controlled by the controller.

The disclosed embodiments relate to multimodal imaging system, comprising: a fiber-coupled fluorescence imaging system, which operates based on ultra-violet (UV) excitation light; and a fiber-coupled optical coherence tomography (OCT) imaging system. The multimodal imaging system also includes a fiber optic interface comprising a single optical fiber, which facilitates light delivery to a sample-of-interest and collection of returned optical signals for both the fluorescence imaging system and the OCT imaging system. During operation of the system, the single optical fiber carries both UV light and coherent infrared light through two concentric light-guiding regions, thereby facilitating generation of precisely co-registered optical data from the fluorescence imaging system and the OCT imaging system.

A method for tissue assessment includes ablating tissue at a site within a body of a living subject using an invasive probe applied to the site. At a first stage in ablation of the tissue, first measurements are made of scattered light intensities from the site at a plurality of different wavelengths. At a second stage in the ablation of the tissue, subsequent to the first stage, second measurements are made of the scattered light intensities from the site at the plurality of different wavelengths. Progress of the ablation is assessed by computing different, respective measures of change in the scattered light intensities at the different wavelengths occurring between the first and second measurements, and comparing the respective measures.

A vital signs monitoring system, the system including: (a) an ear device including: a curved body adapted to a shape of an ear, an upper end, a lower end, two opposite facing sides, a first side adapted to be proximal a skull and a second side adapted to be proximal an earlobe, the ear device including: (i) a temperature sensor adapted to sense a body temperature from a depression between a lower, jawbone and skull; and (b) a control system, including a processor and a memory, configured and operable to control operation of the ear device, to collect signals received from at least one sensor including the temperature sensor, to process the signals to provide medically significant results.

A surgical visualization feedback system is disclosed. The surgical visualization feedback system comprises an emitter assembly configured to emit electromagnetic radiation toward an anatomical structure. The emitter assembly comprises a structured light emitter configured to emit a structured light pattern on a surface of the anatomical structure and a spectral light emitter configured to emit spectral light capable of penetrating the anatomical structure. The surgical visualization feedback system further comprises a waveform sensor assembly configured to detect reflected electromagnetic radiation corresponding to the emitted electromagnetic radiation and a control circuit in signal communication with the waveform sensor assembly. The control circuit is configured to receive an input corresponding to a selected surgical procedure, determine an identity of a targeted structure within the anatomical structure based on the selected surgical procedure and the reflected electromagnetic radiation, and confirm the determined identity of the targeted structure through a user input.

Disclosed are devices, systems, and methods for characterizing tissue using light scattering spectroscopy. A tissue characterization probe includes an elongate member having a proximal end and a plurality of distal probe tips at a distal end. A plurality of illumination fibers extend through the elongate member to the distal probe tips such that each distal probe tip includes at least one illumination fiber. A plurality of detection fibers also extend through the elongate member such that each probe tip includes at least one detection fiber. The disclosed devices and systems beneficially enable characterization of tissues within depths greater than 100 gm. The disclosed devices and systems also enable effective characterization of anisotropic tissues, such as cardiac myocardium.

The catheter probe comprises a catheter tip and a catheter body. The catheter tip comprises a plurality of channels for housing a plurality of optical sensors. Each one of said plurality of optical sensors comprises a ferrule comprising a via, a microlens aligned with said via and attached to said ferrule and an optical fiber for optically coupling said microlens to a monitoring means.

A system and method for manufacturing custom fit artificial nails includes a 3D surface scanning module and a 3D printing module and use thereof. A central processing module is connected to the 3D surface scanning module and the 3D printing module and performs: operating the 3D surface scanning module to obtain an image of a user's hands/feet; processing the image to create an input 3D model of nails of the user; generating an output 3D model corresponding to artificial nails matching dimensions of the user's nails according to the 3D input model; operating the 3D printing module to manufacture artificial nails according to the output 3D model; and generating medical data by correlating the identified features of the user's nails with known medical conditions, in order to diagnose a medical condition of the user which is known to exhibit the identified features as a symptom. Alternatively, or additionally, medicinal ingredient may be included in the artificial nail to treat the medical condition of the user. Embedded devices, sensors or an RFID chip may be integrated into the artificial nail.

Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.