The conversion adapter is provided that includes a radio communication unit that receives biological information based on the digital data transmitted from an external biological sensor by using radio communication; an information processing unit that performs data processing of the biological information based on the digital data; a converter that converts the biological information based on the digital data processed by the information processing unit to biological information based on analog data; and a connection unit that is connectable through wire to an external biological information monitor and that outputs the biological information based on the analog data converted by the converter.

A biological-measurement device includes a light-emitting unit configured to emit light on a body of a test-subject, a light-detecting unit configured to detect light reflected in the body of the test-subject, a control-unit configured to calculate information regarding a pulse-wave of the body of the test-subject based on the light detected by the light-detecting unit, a circuit-board that is flexible and has a first-surface on which the light-emitting unit and the light-detecting unit are provided, the circuit-board further having wiring connecting the light-emitting unit and the control-unit together and connecting the light-detecting unit and the control-unit together, a shielding-unit that is provided on the first-surface, the shielding-unit being situated between the light-emitting unit and the light-detecting unit and configured to protrude beyond the light-emitting unit and the light-detecting unit in a direction perpendicular to the first-surface, and an adhesive-part for firmly contacting with the body of the test-subject.

A method for estimating blood pressure using a blood flow occlusion system applied to an artery includes receiving from a first sensor a sensed signal; processing at a processor the sensed signal to detect beats in a pulsatile signal; determining validity of the detected beats; storing the detected beats and data associated with the detected beats in the sensed signal as the pressure applied to the artery by the blood flow occlusion system deflates towards a level below a nominal level; determining baseline beat characteristics; evaluating the stored beats and associated data to detect change in beat characteristics as compared to the baseline beat characteristics; selecting a beat before the detected change in the beat characteristic as the last beat indicating the onset of the diastolic blood pressure for the artery; determining a value of the applied pressure at the last beat as the diastolic blood pressure for the artery.

Systems and methods for optimizing sensor pressure in blood pressure (BP) measurements using a wearable device are provided. An example method includes recording substantially synchronously photoplethysmogram (PPG) data using a PPG sensor and pressure data using at least one pressure sensor on a wearable device, the wearable device having the PPG sensor, and wherein the at least one pressure sensor is substantially located over a user wrist radial artery while an external force gradually applies and releases pressure a plurality of times to the wearable device, wherein the external force is applied to the radial artery. The PPG data and the pressure data is monitored as the PPG data changes in response to the external force being applied and released multiple times during a period. From the recorded PPG and pressure data, a set data us formed of PPG peak values and pressure values. A curve is fitted through the data set. From the curves apex value a MAP value is determined.

The invention provides a system and method for measuring vital signs (e.g. SYS, DIA, SpO2, heart rate, and respiratory rate) and motion (e.g. activity level, posture, degree of motion, and arm height) from a patient. The system features: (i) first and second sensors configured to independently generate time-dependent waveforms indicative of one or more contractile properties of the patient's heart; and (ii) at least three motion-detecting sensors positioned on the forearm, upper arm, and a body location other than the forearm or upper arm of the patient. Each motion-detecting sensor generates at least one time-dependent motion waveform indicative of motion of the location on the patient's body to which it is affixed. A processing component, typically worn on the patient's body and featuring a microprocessor, receives the time-dependent waveforms generated by the different sensors and processes them to determine: (i) a pulse transit time calculated using a time difference between features in two separate time-dependent waveforms, (ii) a blood pressure value calculated from the time difference, and (iii) a motion parameter calculated from at least one motion waveform.

Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.

This document describes assessing cardiovascular function using an optical sensor, such as through sensing relevant hemodynamics understood by pulse transit times, blood pressures, pulse-wave velocities, and, in more breadth, ballistocardiograms and pressure-volume loops. The techniques disclosed in this document use various optical sensors to sense hemodynamics, such as skin color and skin and other organ displacement. These optical sensors require little if any risk to the patient and are simple and easy for the patient to use.

Embodiments of the present disclosure relate to systems and methods for determining a subject's blood pressure using one or more implantable medical devices (IMDs). In an embodiment, a medical system comprises: at least one implantable medical device configured to sense signals associated with heart sounds of a subject and a processing unit communicatively coupled to the at least one implantable medical device. The processing unit is configured to: receive heart sound signals corresponding to the signals associated with the heart sounds; and calculate a surrogate of the subject's blood pressure using at least one heart sound signal of the received heart sound signals.

The present invention relates to a flexible pressure sensor using a multi-material 3D-printed microchannel mold, and a method for manufacturing the same. An object of the present invention is to provide a flexible pressure sensor using a multi-material 3D-printed microchannel mold, the flexible pressure sensor being formed by using a conductive liquid and an elastomer, having a microchannel formed therein, and having improved flexibility, sensitivity, and stability in comparison to the related art. Another object of the present invention is to provide a method for manufacturing a flexible pressure sensor using a multi-material 3D-printed microchannel mold, in which the flexible pressure sensor is manufactured by using the microchannel mold including microbumps, the microchannel mold being multi-material 3D-printed by using a sacrificial material and a hard material.

The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.