A system and method for detecting a stroke includes a non-contact ocular pulse measurement device configured to output a first and a second ocular pulse measurement signals for each of a patient's eyes, respectively. A computing system has a processor and a memory, and the memory stores instructions that when executed cause the processor to analyze the first and second ocular pulse measurements. An index of difference between the first and second ocular pulse measurements is determined, and a user interface is generated that includes a stroke advisory to the patient based on the index of difference.

A composite ocular blood flow analyzer uses pneumatic tonometric techniques and structures to produce accurate, stable, and repeatable readings of intraocular pressure. A computer processes the intraocular pressure readings to produce data relating to various aspects of ocular blood flow that can be used diagnostically to identify abnormalities in the eye and other parts of the body.

The invention relates to a device and a method, by which the intraocular pressure in a patient's eye is changed by artificially applying a variable stimulation pressure causing, upon reaching specific intraocular pressure values, the presence of characteristic measurement criteria in the retina of the eye, which allow global and local retinal blood pressure values to be derived from the intraocular pressure value. Based on the retinal blood pressure values, which are determined online or preferably offline, local retinal perfusion pressure values (rPP) can be computed and represented in an image of the retina as a pressure mapping image.

A patient data capture and processing system that comprises general programmable medical device (GPMD) and a patient medical device controller (PPS). The patient server is configured to program the function data store of the GPMD, and obtain the data acquired by the GPMD, via the communications connection, wherein the data is stored in patient data records, and wherein the patient server is further configured to extract and output clinically significant events.

The invention concerns a system of measuring ocular pressure, consisting of at least one implant (30) including a pressure sensor (33) and an electronic circuit (32), implanted in the cornea of an eye and an antenna (31) connected to the said circuit and implanted in the sub-conjunctival space; and a unit (50) for processing the representative values of the pressure, received by a radio-frequency link from the said electronic circuit (30).

Generalized transfer functions are available to mathematically derive the more relevant central blood pressure waveform from a more easily measured radial blood pressure waveform. However, these transfer functions are population averages and therefore may not adapt well to variations in pulse pressure amplification (ratio of radial to central pulse pressure). An adaptive transfer function was developed. First, the transfer function is represented in terms of the wave travel time and wave reflection coefficient parameters of an arterial model. Then, the model parameters are estimated from only the radial blood pressure waveform by exploiting the frequent observation that central blood pressure waveforms exhibit exponential diastolic decays. The adaptive transfer function estimated central blood pressure with significantly greater accuracy than generalized transfer functions in the low pulse pressure amplification group while showing similar accuracy to the conventional transfer functions in the higher pulse pressure amplification groups.

The invention relates to a device and a method, by which the intraocular pressure in a patient's eye is changed by artificially applying a variable stimulation pressure causing, upon reaching specific intraocular pressure values, the presence of characteristic measurement criteria in the retina of the eye, which allow global and local retinal blood pressure values to be derived from the intraocular pressure value. Based on the retinal blood pressure values, which are determined online or preferably offline, local retinal perfusion pressure values (rPP) can be computed and represented in an image of the retina as a pressure mapping image.

A method and apparatus for determining intracranial pressure includes a contact lens; a camera for making a plurality of images of at least one eye of a subject; one or more force transducers for controllably applying a force to the eye via the contact lens; a support system for supporting the camera, the contact lens and the one or more force transducers against the eye; and a computing device for controlling the force applied to the eye by the force transducers and stabilizing the force by negative feedback.

A patient data capture and processing system that comprises general programmable medical device (GPMD) and a patient medical device controller (PPS). The patient server is configured to program the function data store of the GPMD, and obtain the data acquired by the GPMD, via the communications connection, wherein the data is stored in patient data records, and wherein the patient server is further configured to extract and output clinically significant events.

A method and apparatus for determining intracranial pressure, includes a contact lens; a camera for making a plurality of images of at least one eye of a subject; one or more force transducers for controllably applying a force to the eye via the contact lens; a support system for supporting the camera, the contact lens and the one or more force transducers against the eye; and a computing device for controlling the force applied to the eye by the force transducers and stabilizing the force by negative feedback.