A cautery safety controller can include a first input to receive a cautery power signal; a first output coupled to a nerve stimulator system; a second input coupled to receive a nerve detected signal; a zero-crossing detector coupled to receive the cautery power signal via the first input and output a nerve sense enable signal via the first output to the nerve stimulator system in response to detecting a zero crossing of the cautery power signal; and a nerve detection decision unit coupled to receive the nerve detected signal via the second input, generate a stop operation signal, and output the stop operation signal via a second output. A cauterizing pencil can be provided with a tap line for providing the cautery power signal. Alternatively, a cautery pad can be provided with a sense electrode for providing the cautery power signal.

Certain methods and systems described herein use a transducer used to produce ablation energy (aka denervation energy) to also evoke a neural response before and/or after denervation energy is delivered. Rather than the neural response being invoked in response to electrical stimulus, it is invoked in response to the transducer (e.g., RF, microwave, or ultrasound transducer) being used to sufficiently heat the nerves in tissue surrounding a biological lumen to an extent that a neural response is evoked without denervating the nerves. That is, the transducer used for performing ablation (aka denervation) is also used to evoke a neural response prior to (and/or after) ablation is performed, by using the transducer to sufficiently heat the nerves in the tissue surrounding the biological lumen to an extent that a neural response is evoked without denervating the nerves. This can reduce the catheter production complexity and costs. Other embodiments are also disclosed.

The present disclosure discloses a monitoring device and a method for controlling a threshold thereof. The monitoring device may include a host. The monitoring device may also include an information acquisition module connected to the host via an electrical signal. The information acquisition module may be configured to acquire an electromyographic signal. The host may include a signal processing module configured to process the electromyographic signal to determine monitoring information corresponding to the electromyographic signal. The monitoring device may further include an output module connected to the signal processing module via an electrical signal. The output module may at least be configured to output the monitoring information. The method may include setting a threshold of the monitoring device, placing an electrode to the target area, and starting the monitoring device. The monitoring device may output prompt information based on the threshold.

A neural interfacing device is disclosed. The neural interfacing device includes a microneedle electrode. The microneedle electrode includes a body having a void formed therein and a plurality of microneedles. The void surrounds the plurality of microneedles, and the plurality of microneedles are bent outward with respect to the body to form a three-dimensional microneedle electrode. Additionally, each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.

Embodiments relate to implantable-lead devices that include one or more materials with altered morphology and methods for making and using the same. Specifically, the morphology of electrodes and/or one or more other implant-device materials can be textured to include micro- and/or nanoscale topographical features, which can reduce in vivo fibrotic response and thereby improve signal-to-noise ratios and short-term extractability of the devices.

Methods and systems for providing closed loop control of stimulation provided by an implantable stimulator device are disclosed herein. The disclosed methods and systems use a neural feature prediction model to predict a neural feature, which is used as a feedback control variable for adjusting stimulation. The predicted neural feature is determined based on one or more stimulation artifact features. The disclosed methods and systems can be used to provide closed loop feedback in situations, such as sub-perception therapy, when neural features cannot be readily directly measured.

Disclosed is an instrument assembly for a selected procedure. The procedure may include a dissection and neural monitoring. The instrument may be insulated to allow for a selected and precise electrical conductive path.

Devices and methods are described herein for treating cardiac conditions using electrical stimulation delivered to and sensing nerve activity from one or both of the AV node and nerve tissue innervating the AV node using one or more neural electrodes positioned in a location within the triangle of Koch of the right atrium.

Provided is a method of analyzing electrical characteristics of nerves, the method including generating an input electrical signal to be applied to a nerve, obtaining an output electrical signal based on measuring a nerve signal generated from the nerve in response to the input electrical signal, obtaining output frequency components, which are frequency components of the output electrical signal, based on converting the output electrical signal into a frequency domain, and obtaining conductance of the nerves and capacitance of the nerves based on the output frequency components.

Provided is a method of analyzing electrical characteristics of nerves, the method including generating an input electrical signal to be applied to a nerve, obtaining an output electrical signal based on measuring a nerve signal generated from the nerve in response to the input electrical signal, obtaining output frequency components, which are frequency components of the output electrical signal, based on converting the output electrical signal into a frequency domain, and obtaining conductance of the nerves and capacitance of the nerves based on the output frequency components.