The present invention is directed to an electrode system for recording nerve action potential (NAP) from surgically exposed nerve and methods for using such an electrode system. Electrophysiological methods are used during repair surgery of peripheral nerve trauma (PNT). PNT is a major medical problem with an annual incidence similar to that of epilepsy. Surgical intervention is provided based on the severity of nerve injury which is determined preoperatively and intraoperatively mainly by electrophysiological assessments. Among those, intraoperative nerve action potential (NAP) or compound action potential (CNAP) recording is preferred for direct assessment of functional continuity of the nerve.

The present invention is directed to an electrode system for recording nerve action potential (NAP) from surgically exposed nerve and methods for using such an electrode system. Electrophysiological methods are used during repair surgery of peripheral nerve trauma (PNT). PNT is a major medical problem with an annual incidence similar to that of epilepsy. Surgical intervention is provided based on the severity of nerve injury which is determined preoperatively and intraoperatively mainly by electrophysiological assessments. Among those, intraoperative nerve action potential (NAP) or compound action potential (CNAP) recording is preferred for direct assessment of functional continuity of the nerve.

A living body guidance device includes: a measurement unit 1 that measures biometric information of a user; a stimulus unit 2 that is installed in contact with the user's body and presents a tactile stimulus to the user; a database unit 3 that has a relationship between the tactile stimulus presented by the stimulus unit and the biometric information according to the tactile stimulus recorded; an input unit 4 that sets target biometric information which is target biometric information that is desired of the user to realize; and a control unit 7 that, when there is a difference between current biometric information which is current biometric information of the user estimated based on the measurement result by the measurement unit and the target biometric information, controls the tactile stimulus presented by the stimulus unit so that the difference is reduced, so as to guide the user so that the current biometric information approaches the target biometric information, based on the relationship recorded in the database unit, by.

A living body guidance device includes: a measurement unit 1 that measures biometric information of a user; a stimulus unit 2 that is installed in contact with the user's body and presents a tactile stimulus to the user; a database unit 3 that has a relationship between the tactile stimulus presented by the stimulus unit and the biometric information according to the tactile stimulus recorded; an input unit 4 that sets target biometric information which is target biometric information that is desired of the user to realize; and a control unit 7 that, when there is a difference between current biometric information which is current biometric information of the user estimated based on the measurement result by the measurement unit and the target biometric information, controls the tactile stimulus presented by the stimulus unit so that the difference is reduced, so as to guide the user so that the current biometric information approaches the target biometric information, based on the relationship recorded in the database unit, by.

A method may include obtaining first and second time series (TS1), (TS2) of stimulation data, and a first and second time series of control data. TS1, TS2 may provide a plurality of pairs of data points such that each of the plurality of pairs include corresponding data points from both TS1 and TS2. The obtained time series may be analyzed by applying an algorithm (Alg) to TS1 and TS2 of stimulation data to create an algorithm value corresponding to each of the plurality of pairs of data points. Alg=(|TS1|+|TS2|)/2−|TS1−TS2|. Positive algorithm values for a predetermined period of time (AlgVarTime) may be summed to create a signal. Peak(s) in the signal may be determined, and a conduction velocity may be determined using a latency and a distance between a stimulus electrode and a recording electrode.

One or more EMG sensors are configured to sense surface-EMG data indicative of muscle movement of the patient; and transmit surface-EMG data. A controller can identify at least one parameter of the surface-EMG data; compare the parameter to a corresponding dystonia-threshold-value; responsive to a determination that the parameter is greater than the corresponding dystonia-threshold-value: issue a visual-engagement command to a visual unit; and issue a tactile-engagement command to a tactile unit.

One or more EMG sensors are configured to sense surface-EMG data indicative of muscle movement of the patient; and transmit surface-EMG data. A controller can identify at least one parameter of the surface-EMG data; compare the parameter to a corresponding dystonia-threshold-value; responsive to a determination that the parameter is greater than the corresponding dystonia-threshold-value: issue a visual-engagement command to a visual unit; and issue a tactile-engagement command to a tactile unit.

The invention relates to an implantable sensor for detecting an electrical excitation of muscle cells, in particular cardiac muscle cells, wherein it is provided that the sensor comprises a dielectric component and a contact point for contacting muscle cells, which is connected to the dielectric component, so that an electric field in the dielectric component, and correspondingly a capacitance of the dielectric component, change with an electrical excitation of the muscle cells. The invention furthermore relates to a system comprising a sensor and an implant.

The invention relates to an implantable sensor for detecting an electrical excitation of muscle cells, in particular cardiac muscle cells, wherein it is provided that the sensor comprises a dielectric component and a contact point for contacting muscle cells, which is connected to the dielectric component, so that an electric field in the dielectric component, and correspondingly a capacitance of the dielectric component, change with an electrical excitation of the muscle cells. The invention furthermore relates to a system comprising a sensor and an implant.

A portable and wearable hand-grasp neuro-orthosis is configured for use in a home environment to restore volitionally controlled grasp functions for a subject with a cervical spinal cord injury (SCI). The neuro-orthosis may include: a wearable sleeve with electrodes; electronics for operating the wearable sleeve to perform functional electrical stimulation (FES) and electromyography (EMG), the electronics configured for mounting on a wheelchair; and a controller configured for mounting on a wheelchair. The controller controls the electronics to read EMG via the sleeve, decode the read EMG to determine an intent of the user, and operate the electronics to apply FES via the sleeve to implement the intent of the user. The neuro-orthosis may restore hand function. The controller may include a display arranged to be viewed by the subject, for example mounted on an articulated arm attached to the wheelchair.