Disclosed herein are joint implants with sensors and methods for manufacturing joint implants with sensors. A knee joint implant according to the present disclosure may include a femoral implant, a tibial implant and a tibial insert disposed therebetween. The tibial implant may include a medial side with a medial central region defined around a medial center, a lateral side with a lateral central region defined around a lateral center and a central region disposed between the medial central region and the lateral central region. At least one sensor and a battery may be disposed within the tibial insert. The medial central region and the lateral central region may be defined by solid volumes extending from a proximal surface to a distal surface of the tibial insert.

Disclosed herein are implants with sensors and methods for powering implants with sensors. A joint implant according to the present disclosure can include a first implant and a second implant in contact with the first implant. The first implant can be coupled to a first bone of a joint. The first implant can include an energy generator coupled to a transducer. The second implant can include at least one sensor, a battery coupled to the at least one sensor, and a receiver coupled to the battery. The receiver can be disposed within the second implant adjacent the transducer. Energy from the energy generator can be transmitted from the transducer of the first implant to the receiver of the second implant.

Disclosed herein are joint implants and methods for intra-operatively detecting joint implant gap. A method for detecting a joint implant gap may include coupling a first implant to a first bone of a joint, coupling a second implant to a second bone of the joint, measuring an amplitude of a magnetic flux density using a magnetic sensor to determine a gap between the first and second implants. The first implant may include at least one magnetic marker. The second implant may be configured to contact the first implant. The second implant may include at least one magnetic sensor to detect the magnetic flux density of the magnetic marker. The gap between the first and second implant may be intra-operatively determined using the measured amplitude of the magnetic flux density.

Disclosed herein are joint implants and methods for tracking joint implant performance. A joint implant according to the present disclosure can include a first implant on a first bone and a second implant on a second bone of a joint. The first implant can include medial and lateral markers. The second implant can include a medial marker reader to identify the medial markers and a lateral marker reader to identify the lateral markers to provide positional data of the first implant with respect to the second implant. The second implant can include a medial load sensor to measure medial load data and a lateral load sensor to measure lateral load data. A processor coupled to the medial marker reader, the lateral marker reader, the medial load sensor, and the lateral load sensor can transmit the positional data, the medial and lateral load data to an external source.

A manipulation assembly comprises: a delivery catheter having a lumen extending therethrough; and a deployment catheter positioned within the lumen of the delivery catheter. The delivery catheter is manipulatable within multiple planes. The deployment catheter is independently manipulatable with respect to the delivery catheter and includes a first lumen and a second lumen. The assembly further comprises an elongate, flexible visualization element positioned within the first lumen of the deployment catheter and extendable distally beyond the delivery catheter. The visualization element is articulatable with respect to the delivery catheter. The assembly further comprises an ablation probe positioned within the second lumen of the deployment catheter and comprises an illumination tool routed through the deployment catheter. The ablation probe is extendable distally beyond the deployment catheter and is positionable off-axis with respect to a longitudinal axis of the delivery catheter. The illumination tool is manipulatable with respect to the delivery catheter.

An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.

The capsule comprises a tubular body and a front-end unit with an helical screw for anchoring the capsule to a wall of a patient's organ. The front-end unit is mobile in relative axial rotation with respect to the tubular body. A disengageable frictional coupling member allows this relative rotation when, for implantation, the tubular body receives an external rotational stress, and that until a predetermined limit torque triggering the disengagement. At explantation, this disengagement is prevented to allow a joint rotation of the tubular body and of the front-end unit and the unscrewing of the helical screw. It is provided for that purpose two conjugated plates facing each other, with flat surfaces such as circular sectors offset in opposite directions with respect to a radial reference plane, in such a way as to form steps providing an anti-disengagement abutment function.

A manipulation assembly includes a delivery catheter having a lumen extending therethrough and a deployment catheter positioned within the delivery catheter. The deployment catheter is independently manipulatable with respect to the delivery catheter. The assembly further includes a visualization element extendable distally beyond the deployment catheter and an ablation probe comprising an energy transmitting surface positionable to ablate tissue adjacent to a distal end of the ablation probe. The ablation probe is extendable distally beyond the deployment catheter.

An implantable intravascular anchor for supporting a device inside a vascular lumen, the anchor comprising a first part configured to expand when extending from a catheter, and to collapse upon retraction into said catheter; a second part for supporting the device in the lumen and a third part, proximal to the first part, and configured so that, upon release from the catheter, it expands in width to engage an interior wall of the lumen and is adapted for securing the anchor against axial movement along the lumen.

Aspects of the disclosure relate to methods of conducting an intraoperative procedure including providing an electrode assembly having a pledget substrate having a surface that is hydrophilic, at least one electrode supported by and positioned within the pledget substrate, and a lead wire assembly interconnected to the at least one electrode. Methods can further include creating an incision to access bioelectric tissue of a patient and applying the pledget substrate to the tissue, such as a nerve, for example. The pledget substrate conforms and fixates to the tissue to secure the electrode assembly in position. The electrode is then activated to record bioelectric responses of or stimulate the tissue. In some embodiments, the pledget substrate includes two bodies, each including at least one electrode, the two bodies being selectively separable so that the bodies can be repositioned with respect to one another.