A medical compound preparation and delivery system, including a delivery device, the device including a depressible trigger operably coupled to move a plunger; a cartridge releasably coupled to the delivery device, the cartridge defining a lumen therethrough to receive at least a portion of the plunger therein; a receptacle defining a cavity therein for receiving a medical compound; a first tube slidably positionable within the cavity of the receptacle; and a second tube slidably positionable within the first tube, wherein the cartridge is slidably positionable within the second tube.

Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of needle penetration. The sampling device may be used through a working channel of a bronchoscope.

A bone marrow access device includes a cannula and a sharp stylet removably positioned in the cannula. The cannula defines a distal opening at a distal tip and a side aperture in a side of the cannula, proximally from the distal opening. The stylet has a sharp distal tip and extends beyond the distal opening. A plug is receivable in the cannula distal to the side aperture to seal the distal opening when the stylet is removed. A method of accessing bone includes inserting the cannula and sharp stylet positioned in the cannula into bone; removing the sharp stylet from the cannula; pushing a plug through the cannula and distal to the side aperture to seal the distal opening of the cannula; and accessing the bone through the side aperture. Accessing the bone can include aspirating bone marrow, injecting a substance, or inserting an instrument into the bone.

An automated tissue coring device that enables controlled and repeatable removal of bone and bone marrow. The device includes a handle, a biasing element coupled to an advancement mechanism, an actuator, and a hollow penetrating needle. A method for bone and bone marrow biopsy, bone marrow aspiration, and bone marrow enhanced tissue repair are introduced using the device as described herein.

The invention relates to a device in the form of a perforating trocar and is intended in particular to be used for surgery and interventional radiology. The device comprises an outer sleeve (5) having a rigid tube (8), and a mandrel (6) having a rod (18). The rod (18) is suitable for sliding in the outer sleeve (5) and has, at its distal end, a perforating tip (21, 33). The rod (18) additionally has a longitudinal groove (20) arranged on the surface of the rod (18), and extending from the distal end to the proximal end of the rod (18), in order to allow the device to slide on a guide pin.

Powered drivers operable to insert an intraosseous device into a bone are disclosed. Some of the present powered drivers include a housing having a distal end and a proximal end. A driveshaft may be located near the distal end of the housing and configured to engage a portion of the intraosseous device. A motor may be disposed in the housing and operable to rotate the driveshaft. A power source may be disposed within the housing and configured to power the motor. The powered drivers may include a lockout operable to prevent activation of the driver for increased safety when handling the driver.

A biopsy device includes a device housing, a linear motor, and a controller circuit. The controller circuit has a processor circuit, a first feedback circuit, and a second feedback circuit. The first feedback circuit and the second feedback circuit operate simultaneously. The processor circuit executes program instructions to control an axial advancement of the distal end of the linear motor shaft in accordance with a linear motor shaft advancement profile based on first control signals received from at least one drive characteristic sensor of the first feedback circuit, and executes program instructions to keep the distal end of the linear motor shaft at a constant axial position, as offset by the position indicated by the linear motor shaft advancement profile, based on second control signals received from the housing position detector of the second feedback circuit so as to compensate for user movement of the device housing.

The invention relates to a trajectory guidance instrument that is securable to a surgical tool for use in conjunction with X-ray machines. More particularly, the device includes a radiolucent outrigger having radiodense indicia disposed on the outrigger so that the radiodense indicia is visible via an X-ray machine to provide an angular trajectory for the instrument. The outrigger is securable to various surgical tools for the purpose of providing real time trajectory guidance to surgeons during a procedure. In general, the precision trajectory guidance instrument comprises a substantially rigid outrigger device which it securable to a portion of the surgical tool for trajectory guidance. The trajectory guidance instrument may be attached with clips, fasteners, adhesives, hook and loop or the like.

A system and method for collecting bone marrow includes a trocar component having an upper handle and an elongate shaft depending from the handle, the shaft having a sharp cutting edge at a lower tip thereof. An introducer component includes a lower handle having an inlet formed therethrough and an introducer cannula communicably connected to the inlet and depending from the lower handle. The introducer cannula has an open distal end. The harvesting component includes a support hub having an aspiration port and a harvesting cannula communicably connected to the aspiration port and depending from the support hub. The trocar and introducer components are introduced into the bone marrow and the trocar component is replaced by the harvesting component. The introducer cannula is withdrawn and interengaged with the support hub of the harvesting component and the assembly is manipulated to drive a blunt end of the harvesting component through the bone marrow without causing undue damage to the bone marrow and constituent cells. Bone marrow is aspirated through fenestrated openings in the side wall of the harvesting cannula.

The invention involves a device and method for acquiring bone marrow aspirate. The system includes an elongated cannulated fastener having a threaded end for attachment to a bone. The threaded portion includes a directional aperture sized to allow marrow to be drawn into the cannula. The directional aperture also allows the user to direct the aperture in a desired direction within the bone for acquisition of the marrow. The distal end of the cannulated fastener includes a connector which may be in the form of a Luer lock to allow vacuum to be applied to the cannula for drawing the marrow into a syringe or the like.