Catheter for real-time evaluation of duodenal ablation, the catheter including an expandable member configured to stretch the duodenal wall and to generate a fixed distance between a center of the catheter and the duodenal wall; a laser transmitting element coupled with the catheter body and configured to transmit a first laser beam and a second laser beam; wherein the first laser beam is configured to cause ablative damage in a region of the duodenal wall as a result of its impingement thereon, and wherein the second laser beam is configured to detect modifications in the region of the duodenal wall resulting from the impingement of the first laser beam thereon.

A microwave ablation system includes: a microwave generator (110) configured to generate a microwave power signal; a microwave antenna (120) coupled to the microwave field to heat at least a portion of the target tissue; a light source (312) for supplying an optical signal to multiple fiber sensors (320) disposed on the microwave antenna (120); a photodetector (316) for detecting an optical signal reflected from the fiber sensors (320) and producing an electrical detection signal; a demodulation device for demodulating the electrical detection signal; and a processor for processing the demodulated signal to obtain temperature measurements at different locations in the ablation zone, which may be displayed to a user to facilitate the performance of an ablation procedure. The multiple fiber sensors (320) may include multiple fiber Bragg gratings etched in an optical fiber (315), which are immune to electromagnetic interference.

An anti-contamination laser surgery device with a built-in optical element, including an inner cylinder, an outer cylinder, a first unit configured to enable the inner cylinder and the outer cylinder to be telescopic, a lens moving unit, a two-dimensional laser scanning unit, a real-time monitoring unit, and a second unit configured to perform unidirectional laminar flow ventilation. A head end of the inner cylinder and a tail end of the outer cylinder are matched and connected by the first unit. The two-dimensional laser scanning unit and the real-time monitoring unit are arranged at the head end of the outer cylinder, and the lens moving unit is arranged in the inner cylinder and close to the head end of the inner cylinder. The second unit is arranged close to a tail end of the inner cylinder.

A microwave generator includes a microwave signal generator configured to deliver a microwave signal to a microwave instrument coupled to the microwave generator and a generator controller storing a plurality of resistance value indicators. A device ID reader is configured to measure a resistance of the coupled microwave instrument. The generator controller is configured to compare the measured resistance of the coupled microwave instrument with the plurality of resistance value indicators to identify a type of the coupled microwave instrument. An instrument monitoring controller is configured to communicate a data request to the coupled microwave instrument based on the identified type of the coupled microwave instrument. The generator controller is configured to set at least one operating threshold of the microwave generator based on one of an operating configuration corresponding to one of the plurality of resistance value indicators or data communicated from the coupled microwave instrument.

A treatment system can include a channel generation system configured to expose an infected region of a target tissue with a laser beam traveling along an optical axis and focused at a focal volume located in or adjacent to the target tissue. The laser beam can have a wavelength ranging from about 100 nm to about 400 nm. The laser beam can be configured to generate at least a first channel in the infected region. The treatment system can also include a detection system configured to detect a first radiation generated by one or more of (i) the target tissue, (ii) a fungi coupled to the infected region in the target tissue, and (iii) an adjacent tissue located proximal to the target tissue as a result of interaction with the laser beam. The treatment system can also include a delivery system configured to deposit an active treatment agent in the at least first channel.

A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes a first light source (124), a plurality of light guides (122A), a multiplexer (128) and a multiplexer alignment system (142). The first light source (124) generates light energy. The plurality of light guides (122A) are each configured to alternatingly receive light energy from the first light source (124). Each light guide (122A) has a guide proximal end (122P). The multiplexer (128) receives the light energy from the first light source (124). The multiplexer (128) alternatingly directs the light energy from the first light source (124) to each of the plurality of light guides (122A). The multiplexer alignment system (142) is operatively coupled to the multiplexer (128). The multiplexer alignment system (142) includes a second light source (270) that generates a probe source beam (270A) that scans the guide proximal end (122P) of each of the plurality of light guides (122A).

A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (208A) or a heart valve within a body (107) of a patient (109) includes an energy source (124), a balloon (104), an energy guide (122A), and a tissue identification system (142). The energy source (124) generates energy. The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) includes a balloon wall (130) that defines a balloon interior (146). The balloon (104) can be configured to retain a balloon fluid (132) within the balloon interior (146). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146) so that plasma bubbles (134) are formed in the balloon fluid (132) within the balloon interior (146). The tissue identification system (142) can be configured to acoustically analyze tissue within the treatment site (106).

An optical fiber state detection system includes: a first light source that outputs a monitor-related light for monitoring a state of an optical fiber; a reflection mechanism that reflects the monitor-related light propagated through the optical fiber; a light receiving part that receives a reflected light reflected by the reflection mechanism; a tap coupler provided between the reflection mechanism and both the first light source and the light receiving part such that the first light source and the light receiving part are connected the tap coupler; and a control part. Further, when the control part detects that a received optical power of the reflected light is greater than 0 and lower than a predetermined threshold value, the control part outputs information on a decrease in the received optical power to outside.

Systems, devices and methods are provided to deliver microporation medical treatments to improve biomechanics, wherein the system includes a laser for generating a beam of laser radiation on a treatment-axis not aligned with a patient's visual-axis, operable for use in subsurface ablative medical treatments to create an array pattern of micropores that improves biomechanics. The array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern.

A laser system includes a laser source generating a laser beam having ultra-short pulses; a laser delivery assembly optically receiving the laser beam and comprising: a beam splitter configured to split the laser beam between a first beam delivery path and a second beam delivery path; and at least one focusing lens optically coupled to the beam splitter and configured to focus the laser beam from each of the first beam delivery path and the second beam delivery path to a focal point on a predefined plane; wherein the first beam delivery path intersects the predefined plane at a first angle, the second beam delivery path intersects the predefined plane at a second angle, and a first pulse from the first beam delivery path and a second pulse from the second beam delivery path are coincident at the focal point.