Ablation systems and methods of the present disclosure include a catheter including one or more image sensors. The one or more image sensors can facilitate, for example, positioning an ablation electrode at a treatment site of an anatomic structure and, additionally or alternatively, can facilitate controlling delivery of therapeutic energy to a treatment site of an anatomic structure.

Aspects of the present disclosure are directed to, for example, a high-thermal-sensitivity ablation catheter tip including a thermally-insulative ablation tip insert supporting a plurality of temperature sensors positioned within longitudinally-extending sensor channels and a radially-extending sensor channel within the tip insert. The sensor channels position the temperature sensors in thermal communication with a conductive shell that encapsulates, or essentially encapsulates, the ablation tip insert and the plurality of temperature sensors. Also disclosed is a method of controlling the temperature of an ablation catheter tip while creating a desired lesion using various ablative energies and energy delivery methodologies.

Provided in accordance with the present disclosure is a microwave ablation system including a microwave ablation probe configured to deliver energy to a target volume of tissue during an ablation procedure, at least one temperature sensor configured to determine a temperature of the target volume of tissue at a plurality of points in time during the ablation procedure, and a computing device operably coupled to the microwave ablation probe and the at least one temperature sensor. The computing device includes a processor and a memory storing instructions, which causes the computing device to load a temperature accumulation profile corresponding to the target volume of tissue, and dynamically control the microwave ablation probe in accordance with the temperature of the target volume of tissue at each of the points in time such that the temperature of the target volume of tissue follows the temperature accumulation profile during the ablation procedure.

The present disclosure provides devices, systems and methods for hyperthermia cancer treatment by supplying ferromagnetic nanoparticles to a target area having or suspected of having cancer cells, the ferromagnetic nanoparticles are configured to attach to the cancer cells and heat by absorbing magnetic energy, and radiating the target area with microwaves such that the target area is within a nearfield range of the radiated microwave, and the microwave radiation nearfield is magnetically biased such that the ratio of magnetic energy to electric energy is greater than 1.

A multiple thermocouple assembly with a reduced wire count is configured for use in an ablation catheter tip. In at least one embodiment, the assembly comprises a first metal material comprising a plurality of junctions; a plurality of conductors comprising a second metal material, each conductor connected to the first metal material at one of the plurality of junctions; and a common conductor that is physically paired with at least one of the plurality of conductors at a corresponding common conductor junction such that the common conductor forms a thermocouple pair with each of the plurality of conductors.

Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.

An apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current. An apparatus in accord with the present disclosure includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present disclosure includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.

Spinal tumor ablation devices and related systems and methods are disclosed. Some spinal tumor ablation devices include electrodes that are fixedly offset from one another. Some spinal tumor ablation devices include a thermal energy delivery probe that has at least one temperature sensor coupled thereto. The position of the at least one temperature sensor relative to other components of the spinal tumor ablation device may be controlled by adjusting the position of the thermal energy delivery probe in some spinal tumor ablation devices. Some spinal tumor ablation devices are configured to facilitate the delivery of a cement through a utility channel of the device.

Apparatus and methods for delivering coolant to an energy delivery device used to treat tissue with electromagnetic energy. A cooling system includes a pump that is configured to pump a coolant to the energy delivery device.

A medical apparatus includes a probe, which includes an insertion tube configured for insertion into a body cavity of a patient, a distal structure connected distally to the insertion tube and including a plurality of electrodes, which are configured to contact tissue within the body, and temperature sensors fixed to the distal structure and configured to output signals indicative of a temperature of the tissue contacted by the electrodes. The apparatus further includes an electrical signal generator configured to apply between one or more pairs of the electrodes bipolar pulses having an amplitude sufficient to cause irreversible electroporation (IRE) in the tissue contacted by the spines, and a controller configured to control a timing of the bipolar pulses applied by the electrical signal generator responsively to the signals output by the temperature sensors.