A fiber optic probe includes a first diffuse reflectance spectroscopy fiber, a second diffuse reflectance spectroscopy fiber, and a temperature sensor at a distal end of a temperature sensor fiber. Other embodiments further include a treatment fiber for delivering a high optical power density of light to a tumor and a dosimetry fiber for monitoring the light flux of the treatment fiber. Other embodiments utilize an image-guidance step in a method of using the fiber optic probe.

The various examples of the present disclosure are directed towards a multi-physics controller that can predict and monitor ablation procedures. In some examples of the present disclosure, fat saturation images can be used to create custom microwave ablation bioelectric/biothermal models. In some examples of the present disclosure, a deformation correction methodology can be used. Thereby, microwave and mechanics computational models can forecast therapeutic delivery intraoperatively while correcting for deformation.

A control circuit is disclosed that comprises a resistor and a switch network. The switch network is configured to transition between a plurality of states corresponding to a plurality of operational modes of a surgical instrument. In a first phase of a control signal, the control circuit is configured to communicate surgical instrument information to a surgical generator. In the second phase of the control signal and when the at least one switch of the switch network is in a first state of the plurality of states, the control circuit is configured to provide an output corresponding to one of the plurality of states. In the second phase of the control signal and when the at least one switch of the switch network is in a second state of the plurality of states, the control circuit is configured to provide a second output.

Spinal tumor ablation devices and related systems and methods are disclosed. Some spinal tumor ablation devices include two conductors and one or more thermocouples. The thermocouple to measure a temperature at a location on one of the conductors. A generator can produce an electrical alternating current to be conducted between the first conductor and the second conductor via tissue within a desired ablation region. A processor may monitor temperature and impedance and control an output of the generator when the impedance of the tissue increases and stop the generator when the thermal energy delivered to the tissue reaches a target threshold.

Tumor ablation devices and related systems and methods are disclosed. Some tumor ablation devices include an RF energy delivery probe with two conductors and one or more thermocouples. The thermocouple measures a temperature at a location on one of the conductors. A generator can produce a current to be conducted between the first conductor and the second conductor via tissue within a desired ablation region. The ablation regions created by the RF energy delivery probe are symmetric about poles of the first conductor and the second conductor. A distal portion of the RF energy delivery probe may articulate, enabling a user to position the RF energy delivery probe in a proper position to ablate the tumor. The thermocouples may be disposed on a flexible or wired thermocouple circuit that is disposed between insulators.

Systems and methods for applying ultrasound sonication to temporarily disrupt a patient's blood-brain barrier (BBB) include storing threshold values of an acoustic response level, an acoustic response dose and a tissue response dose associated with a target BBB region and its surrounding regions based on anatomical characteristics thereof; causing the ultrasound transducer to transmit one or more pulses/waves; measuring the acoustic response level, the acoustic response dose, and/or the tissue response dose associated with the target BBB region and/or its surrounding regions; comparing the measurement with a corresponding stored threshold value; and operating the transducer based at least in part on the comparison.

An electrical conductor, such as a wire or catheter, which is coated circumferentially with a ferromagnetic material in a selected region, is fed from a high frequency alternating current source. The ferromagnetic material has a quick response in heating and cooling to the controllable power delivery. The ferromagnetic material can be used for separating tissue, coagulation, tissue destruction or achieving other desired tissue effects in numerous surgical procedures.

A method for determining a change of temperature of an object. The method may include heating an object and measuring scattering parameters (S-parameters) of scattered microwave electric fields from the object. A distorted Born iterative method may be used to determine a change of a dielectric property of the object based on the measured S-parameters. A change of temperature of the object may be determined based on the change of the dielectric property of the object.

Described embodiments include an apparatus that includes an electrical interface and a processor. The processor is configured to receive, via the electrical interface, a temperature sensed by a temperature sensor at a distal end of an intrabody probe, to estimate a temperature of tissue of a subject, based on the sensed temperature and a parameter of an ablating current driven, by an ablation electrode at the distal end of the intrabody probe, into the tissue, and to generate an output in response to the estimated temperature. Other embodiments are also described.

Methods and systems for treating a patient using a time varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient. An exemplary method includes charging an energy storage device and discharging the energy storage device to a magnetic field generating device to generate the time-varying magnetic field. The time-varying magnetic field is applied to the patient.