A device for ablating target tissue of a patient with electrical energy is provided. An elongate shaft includes a proximal portion and a distal portion, and a radially expandable element is attached to the distal portion. An ablation element for delivering electrical energy to target tissue is mounted to the radially expandable element. The device can be constructed and arranged to ablate the duodenal mucosa of a patient while avoiding damage to the duodenal adventitial tissue. Systems and methods of treating target tissue are also provided.

Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.

The present disclosure provides catheter systems, electrode assemblies, and methods for electrically stimulating one or more points about the circumference of the renal artery to provide real time intraprocedural operational feedback to the operator of a renal denervation procedure to allow for more precise and thorough ablation of the renal artery and better patient outcomes. In many embodiments, an electrode assembly is provided that includes multiple splines that extend from an insulated proximal hub to an insulated distal hub and are interconnected to an electrical wire to allow the splines to independently function as electrical stimulation electrodes. The electrically active splines can then be energized at one or more desired points during a renal denervation procedure to provide operational feedback.

Ablation catheters and systems include coaxial catheter shafts with an inner lumen for delivering an ablative agent and an outer lumen for circulation of a cooling element about the catheter. Induction heating is used to heat a chamber and vaporize a fluid within by wrapping a coil about a ferromagnetic chamber and providing an alternating current to the coil. A magnetic field is created in the area surrounding the chamber which induces electric current flow in the chamber, heating the chamber and vaporizing the fluid inside. Positioning elements help maintain the device in the proper position with respect to the target tissue and also prevent the passage of ablative agent to normal tissues.

A system for use in a renal denervation procedure includes a catheter having proximal and distal end portions, a sensor configured to sense a condition of one or more nerves, the sensor operatively associated with the distal end portion of the catheter, and at least one electrode disposed on the distal end portion of the catheter for delivering energy to renal tissue. A catheter includes a catheter body defining a distal end portion and a proximal end portion, and a sensor for sensing a renal sympathetic nerve, the sensor disposed on the distal end portion of the catheter body, wherein the sensor is configured to sense an electromagnetic signal from the renal sympathetic nerve.

An improved gastric tube for displacing a section of an esophagus during cardiac ablation procedures is disclosed. The improved gastric tube is an elongated flexible tube designed to be inserted in the esophagus of a patient and extended past the portion of the esophagus which overlies the heart. The improved gastric tube includes a first lumen extending the length of the tube which receives a control wire, plastic stylet, or other apparatus which would function for displacement of the portion of the esophagus overlying the heart. A second lumen is included which extends to the operative section of the gastric tube, where the esophagus overlies the heart, so that contrast liquid or cooling liquid can be injected into the esophagus at that location. A temperature sensor can also be included to measure the temperature of the esophageal wall, as well as electrodes to connect to a three-dimensional mapping system.

Provided are a method for adjusting an in-tank pressure of a working medium storage tank and an apparatus for the same. The method includes: acquiring a backflow temperature collected by each of first thermocouples; counting the number of target backflow paths whose backflow temperature reaches a preset temperature; and adjusting an in-tank pressure of the working medium storage tank to a target in-tank pressure corresponding to the number of the target backflow paths according to the number of the target backflow paths and a corresponding relationship between a preset number of backflow paths and the in-tank pressure. The control box determines the target in-tank pressure corresponding to the number of the target backflow paths to realize automatic adjustment of the in-tank pressure of the working medium storage tank.

A cryoablation method, system, and device that allows for real-time and accurate assessment and monitoring of PV occlusion and lesion formation without the need for expensive imaging systems and without patient exposure to radiation. The system includes a cryoballoon catheter with a cryoballoon, a distal electrode, a proximal electrode, and a temperature sensor. Impedance measurements recorded by the electrodes may be used to predict ice formation, quality of pulmonary vein occlusion, and lesion formation.

The present invention relates to systems for use for radio frequency ablation. The systems can include one or more of an ablation tool, power source for use with the ablation tool and a backstop for use in conjunction with the ablation tool during surgical procedures. Preferred ablation tools comprise a series of three or more blade-shaped electrodes disposed in a linear, curved, curvilinear or circular array. The backstops are useful for reducing direct physical and thermal heat transfer injuries to the patient or surgeon during procedures using radiofrequency (RF) ablation devices.

Methods and systems provide a body surface electrode, such as a patch, and, for example, a backpatch, which automatically detects detachment from the skin and/or proximity thereto, within a predetermined limit, and hence, the electrode coming out of contact with and/or proximity to the skin. Once the detachment is detected, the disclosed system instantaneously terminates pulse delivery to a pulse delivery electrode from an IRE generator, which generates the delivered pulses. By instantaneously terminating pulse delivery, damage to body tissues from overheating caused by pulses is minimized or eliminated.