Patent classifications
A61K8/066
Bicontinuous microemulsion composition and cosmetic
The present invention provides a bicontinuous microemulsion composition, including: (A) polyglycerin group-containing organo(poly)siloxane shown by the general formula (1): ##STR00001##
wherein R.sup.1 represents an alkyl group or a phenyl group, R.sup.2 represents a group having a polyglycerin structure shown by the formula (2) or the formula (3), R.sup.3 represents R.sup.1 or R.sup.2, “a” is 0 to 6, “b” is 0 to 4, a+b is 0 to 10, and at least one of R.sup.3 is R.sup.2 when “b” is 0: ##STR00002##
wherein R.sup.4 represents an alkylene group or an aralkylene group, “c” is 0 to 10, and “d” is 2 to 6; (B) silicone oil having a viscosity of 20 mm.sup.2/s or less at 25° C., volatile hydrocarbon oil, or ester oil; and (C) water. This provide a transparent bicontinuous microemulsion composition in which anionic or cationic surfactant, and water-soluble monovalent or polyvalent alcohol are unnecessary; and a cosmetic with excellent pleasantness of use.
DUAL-FUNCTION STARCH-BASED COMPOSITE NANOPARTICLES AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF
The present application discloses dual-function starch-based composite nanoparticles as well as a preparation method and application thereof. The preparation method comprises: hydrolyzing starch to form linear dextrin, grading the linear dextrin by using an alcohol-alcohol gradient precipitation method to obtain linear dextrin having homogeneous molecular weight distribution; oxidizing the linear dextrin by adopting an oxidation system to obtain oxidized dextrin; carrying out complex reaction on the oxidized dextrin and curcumin to form an oxidized dextrin-curcumin complex; and forming an oxidized dextrin-curcumin/chitosan hydrochloride composite nanoparticles from the oxidized dextrin-curcumin complex and chitosan hydrochloride. The aqueous phase solution of the dual-function starch-based composite nanoparticles containing gel polysaccharide is uniformly mixed with primary emulsion, calcium ion induction is carried out on the obtained double emulsion to obtain double-emulsion gel.
Improvements in or Relating to Organic Compounds
Disclosed is a composition comprising at least one core-shell microcapsule in a suspending medium. The microcapsule comprises a core and a shell around said core. The shell comprises a hyperbranched polysaccharide selected from the group consisting of amylopectins, dextrins, hyperbranched starches, glycogen and phytoglycogen and mixtures thereof.
COSMETIC COMPOSITION WITH MULTIPLE EMULSION FORMULATION HAVING LAMELLAR LIQUID CRYSTAL STRUCTURE
The present invention relates to a cosmetic composition of a multiple emulsion formulation having a lamellar liquid crystal structure, and a method for preparing the same. More particularly, the cosmetic composition is prepared using different single emulsification type emulsions, i.e. a W/O type emulsion and an O/W type emulsion which has a lamellar liquid crystal structure, or using a mixture having constituent ingredients thereof. Thus, the present invention has effects of stably maintaining effective ingredients of the cosmetic composition, and enhancing the feeling of use.
Compositions having a plurality of discrete emulsions
A cosmetic composition comprising a first emulsion and a second emulsion and optionally one or more additional emulsions, each of said two or more emulsions being discretely contained within the composition and comprising an inner phase and an outer phase, each of said two or more emulsions being independently a water-in-oil emulsion, an oil-in-water emulsion, an oil-in-oil emulsion, a polyol-in-oil emulsion, a water-in-silicone emulsion, a silicone-in-water emulsion, or a polyol-in-silicone emulsion in physical contact with at least one other emulsion, at least one of said two or more emulsions being visually distinct from the others, and each of said two or more emulsions as well as said composition being independently both physically and visually stable within the composition for at least six months at ambient temperature.
STABILISED MULTIPLE EMULSIONS AS SKIN PROTECTION PRODUCT
The invention relates to stabilised multiple emulsions comprising the compounds a), b) and c), methods for the stabilisation of multiple emulsions and the use of multiple emulsions as skin protection products, in particular for protection against aqueous noxa, where: a) at least one aliphatic unbranched diol with 2 to 4 carbon atoms in the hydrocarbon chain, b) at least one further branched or unbranched aliphatic diol with 4 to 12 carbon atoms in the hydrocarbon chain that is different from a), whereby the hydrocarbon chain may be interrupted by an oxygen atom, c) at least one single-value aliphatic alcohol with 12 to 30 carbon atoms in the hydrocarbon chain.
Double Emulsions
A water-in-oil-in-water (W.sub.1/O/W.sub.2) emulsion comprising a lipid phase (O) and a water phase (W.sub.2), the lipid phase being distributed inside the water phase, wherein the lipid phase contains water droplets (W.sub.1), wherein the water content inside the lipid phase is between 10 wt % and 80 wt % relative to total weight of the lipid phase, wherein the water droplets are stabilized inside the lipid phase by an emulsifier composition, wherein the emulsifier composition comprises an Acetone-insoluble (AI) component containing a Phosphatidyl Choline (PC), a Phosphatidyl Inositol (PI), a Phosphatidyl Ethanolamine (PE) and a Phosphatidic Acid (PA), wherein PC is at most 15.5% relative to the total weight of the emulsifier composition and wherein the emulsifier composition has a phospholipid weight ratio R of at most 65%, the ratio R being defined according to Formula R(in %)=100(PC+PI+PE+PA)/AI.
NOVEL APPLICATIONS AND FORMULATIONS OF OPTIMIZED, MODIFIED HUMAN EMBRYONIC FERTILITY CULTURE MEDIA WITH BIGUANIDES AND/OR FUNCTIONAL EQUIVALENTS
A dermatological preparation comprises an optimized, modified human embryonic fertility culture media with biguanides and/or functional equivalents and the use of said preparation for skin care, hair care, or body care, or dental procedures, or for regenerative medicine such as promoting wound or bone healing. The preparation is formulated to target the hypoxic microenvironment niches of the skin tissue in combination with optimal concentration of nutrients, ions and minerals; to stimulate existing stem cells to trigger the capacity of stem cells to divide and renew and differentiate into specialized cells; and to stimulate molecular and physiological processes, e.g., autophagy, to replenish the substrate pool through the recycling of organelles and the recycling of old damaged proteins and countering free-radical damage to promote anti-aging.
POROUS COMPOSITE PARTICLES AND COSMETIC COMPOSITIONS COMPRISING THE SAME
Disclosed are porous composite particles and compositions comprising the same. The porous composite particles comprising base of an amphiphilic or hydrophobic polymer and 0.1 to 20% of a pigment based on the total weight of porous composite particles, where said particles have 50 to 95 vol % internal porosity and an outer surface which is either continuous and devoid of pores or is discontinuous comprising plurality of pores whose total area is 0.01 to 30% of the total outer surface area. When typically applied, the compositions impart improving the characteristics of skin.
Compositions comprising a silicone surfactant, a silicone elastomer powder and an organo-modified clay
This invention relates to a composition in the form of a water-in-oil emulsion that comprises an aqueous phase dispersed in a continuous oily phase, wherein the continuous oily phase comprises: at least one organo-modified clay, with a content by weight ranging from 0.5% to 1% relative to the total weight of said composition; at least one silicone elastomer powder coated with a silicone resin, with a content by weight ranging from 5% to 12% relative to the total weight of said composition; and at least one silicone surfactant with a content by weight ranging from 1.4% to 3% relative to the total weight of said composition; and wherein the dispersed aqueous phase comprises: water at a content by weight ranging from 15% to 25% relative to the total weight of said composition; and ethanol at a content by weight ranging from 8% to 18% relative to the total weight of said composition.