Biocompatible, bistable or multistable (P-Type) photochromic nanoparticles or microparticles that can be embedded in the skin using techniques such as those used to create a tattoo with tattoo ink. The color of the tattoo using the biocompatible bistable or multistable photochromic microparticles can be written, erased or changed, and re-written locally in the skin by irradiation with light of appropriate wavelengths. Some formulations with much higher sensitivity to UV light than visible light can also be used as short-term intradermal colorimetric UV dosimeters that can be reset and re-used on an hourly or daily basis. These particles can be uniform aggregates or polymers containing P-type photochromic dyes, microencapsulated or core-shell structures with cores containing P-type photochromic dyes, or solid particulate materials with P-type photochromic dyes adsorbed on the surface or within their pores.

A method for reducing hyaluronidase activity and promoting hyaluronic acid production in skin comprising topically applying to skin in need thereof a composition comprising an effective amount of Centella asiatica stem cells to reduce hyaluronidase activity in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate to promote hyaluronic acid production in skin, and an effective amount of tripeptide-1 to promote hyaluronic acid production in skin.

A method for reducing hyaluronidase activity and promoting hyaluronic acid production in skin comprising topically applying to skin in need thereof a composition comprising an effective amount of Centella asiatica stem cells to reduce hyaluronidase activity in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate to promote hyaluronic acid production in skin, and an effective amount of tripeptide-1 to promote hyaluronic acid production in skin.

The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.

The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.

Disclosed are compositions and methods for their use that can be used in cosmetic applications. The composition can include an effective amount of a Centella asiatica stem cells to reduce the activity of hyaluronidase in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate or Alpinia galanga leaf extract to promote the production of hyaluronic acid in skin, an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin, and a dermatologically acceptable vehicle.

Disclosed are compositions and methods for their use that can be used in cosmetic applications. The composition can include an effective amount of a Centella asiatica stem cells to reduce the activity of hyaluronidase in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate or Alpinia galanga leaf extract to promote the production of hyaluronic acid in skin, an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin, and a dermatologically acceptable vehicle.

The present disclosure is in the field of ointments which can be useful for the treatment of diseases or conditions associated with lipid barrier damage of the skin. The ointment comprises a semifluorinated alkane and a solid thickening agent, e.g., a wax, a triglyceride, cetyl alcohol, cetyl palmitate, or tetradecanol.

A subject-matter of the present invention is a cosmetic composition comprising: at least one polysaccharide alkyl ether comprising at least two different monosaccharide units, each unit comprising at least one hydroxyl group substituted by a C.sub.1-C.sub.24, preferably C.sub.1-C.sub.10, alkyl chain, at least one non-volatile polar hydrocarbon first oil, at least one second oil, incompatible with the first oil or oils, chosen from non-volatile silicone oils, from non-volatile fluorinated oils, or their combinations, optionally at least one non-volatile third oil, different from the first oil or oils and different from the second oil or oils, chosen from polar or non-polar hydrocarbon oils, phenylated silicone oils not comprising a dimethicone fragment, or their mixtures, the (polysaccharide alkyl ether/polysaccharide alkyl ether+first oil(s)+if appropriate third oil(s))*100 ratio by weight varying from 10% to 32%. The invention also relates to a method for making up and/or caring, in particular for the lips, which the abovementioned composition is applied.

A subject-matter of the present invention is a cosmetic composition comprising: at least one polysaccharide alkyl ether comprising at least two different monosaccharide units, each unit comprising at least one hydroxyl group substituted by a C.sub.1-C.sub.24, preferably C.sub.1-C.sub.10, alkyl chain, at least one non-volatile polar hydrocarbon first oil, at least one second oil, incompatible with the first oil or oils, chosen from non-volatile silicone oils, from non-volatile fluorinated oils, or their combinations, optionally at least one non-volatile third oil, different from the first oil or oils and different from the second oil or oils, chosen from polar or non-polar hydrocarbon oils, phenylated silicone oils not comprising a dimethicone fragment, or their mixtures, the (polysaccharide alkyl ether/polysaccharide alkyl ether+first oil(s)+if appropriate third oil(s))*100 ratio by weight varying from 10% to 32%. The invention also relates to a method for making up and/or caring, in particular for the lips, which the abovementioned composition is applied.