The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

An itching water applicable to postoperative wound itching and a process for the production of it are provived. The itching water comprising Lignum Aquilariae Resinatum, Radix Notoginseng, Cornus Officinalis, Fructus Gardenia, Radix Flemingiae, Myrrh, Fructus Chaenomelis, Radix Scutellariae, Rhizoma Alismatis, Zanthoxylum Pipertum DC, Salvia Miltiorrhiza, Radix Angelicae Sinensis, Rheum Palmatum, Angelica Dahurica, Acorus tatarinowii, Radix Paeoniae Rubra, Lignum Sappan, Cinnamomum Cassia Presl, Radix Sanguisorbae, Asarum Sieboldii, Rhizoma Atractylodis, Pinellia Ternate, Common Clubmoss Herb, Pyritum, Radix Curcumae Aromaticae, Radix Saposhnikoviae, Rhizoma et Radix Notopterygii, Cortex Moutan, Boswellia Carteri, Radix Linderae and medical ethanol. The itching water of the invention has reasonable composition, less dosage, environment protection, simple operation, remarkable therapeutic effect and less side effects.

An itching water applicable to postoperative wound itching and a process for the production of it are provived. The itching water comprising Lignum Aquilariae Resinatum, Radix Notoginseng, Cornus Officinalis, Fructus Gardenia, Radix Flemingiae, Myrrh, Fructus Chaenomelis, Radix Scutellariae, Rhizoma Alismatis, Zanthoxylum Pipertum DC, Salvia Miltiorrhiza, Radix Angelicae Sinensis, Rheum Palmatum, Angelica Dahurica, Acorus tatarinowii, Radix Paeoniae Rubra, Lignum Sappan, Cinnamomum Cassia Presl, Radix Sanguisorbae, Asarum Sieboldii, Rhizoma Atractylodis, Pinellia Ternate, Common Clubmoss Herb, Pyritum, Radix Curcumae Aromaticae, Radix Saposhnikoviae, Rhizoma et Radix Notopterygii, Cortex Moutan, Boswellia Carteri, Radix Linderae and medical ethanol. The itching water of the invention has reasonable composition, less dosage, environment protection, simple operation, remarkable therapeutic effect and less side effects.

Disclosed herein is a pharmaceutical composition for preventing, alleviating or treating neurodegenerative diseases. The pharmaceutical composition contains, as active ingredients, Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum. The pharmaceutical composition is prepared by a method including the steps of: mixing Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum to obtain a mixture, and extracting the mixture to obtain a mixture extract; filtering the mixture extract; concentrating the mixture extract; and drying the mixture extract.

Disclosed herein is a pharmaceutical composition for preventing, alleviating or treating neurodegenerative diseases. The pharmaceutical composition contains, as active ingredients, Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum. The pharmaceutical composition is prepared by a method including the steps of: mixing Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum to obtain a mixture, and extracting the mixture to obtain a mixture extract; filtering the mixture extract; concentrating the mixture extract; and drying the mixture extract.

A method of treating a glucose-6-phosphate dehydrogenase deregulated disorder in a subject in need thereof, the method involving administering a therapeutically effective amount of oleanolic acid or a conjugate salt thereof or prodrug thereof to the subject. The glucose-6-phosphate dehydrogenase deregulated disorder can be BCL2 associated athanogene myofibrillar myopathy, amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, or Alzheimer disease.

A method of treating a glucose-6-phosphate dehydrogenase deregulated disorder in a subject in need thereof, the method involving administering a therapeutically effective amount of oleanolic acid or a conjugate salt thereof or prodrug thereof to the subject. The glucose-6-phosphate dehydrogenase deregulated disorder can be BCL2 associated athanogene myofibrillar myopathy, amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, or Alzheimer disease.

The present invention relates to formulations made up from extracts from Ganoderma lucidum, rhizome of Coptis chinensis, Radix astragali, Nelumbo nucifera Gaertn, Chaenomeles speciosa, and Fructus Aurantii. Pursuant to the invention, the formulations are used to treat obesity and the biological sequelae of obesity including cholesterol levels and glucose levels. While not limited to any particular mechanism of action the formulations may assert their effects by altering gene expression, in particular, the expression of PPAR, FABP4, CPT1, UCP2, and AMPK.

The present invention relates to formulations made up from extracts from Ganoderma lucidum, rhizome of Coptis chinensis, Radix astragali, Nelumbo nucifera Gaertn, Chaenomeles speciosa, and Fructus Aurantii. Pursuant to the invention, the formulations are used to treat obesity and the biological sequelae of obesity including cholesterol levels and glucose levels. While not limited to any particular mechanism of action the formulations may assert their effects by altering gene expression, in particular, the expression of PPAR, FABP4, CPT1, UCP2, and AMPK.