The present disclosure comprises devices, systems, and methods having an inverted sheath configured to cover, and in some instances constrain, a medical device and to retract through eversion, thus enabling the deployment of medical device at the treatment site. A constraining sheath can evert hydraulically. A constraining sheath can be configured to neck down a medical device to achieve a lower delivery profile. Furthermore, a constraining sheath can comprise a balloon to expand or positionally or structurally adjust a medical device.

A product management display system for merchandising product on a shelf includes a divider secured to a support structure and a barrier that is moveable by rotation between a folded position and an upright position without a rotation biasing element. A product positioned in the system can contact the barrier when the product moves toward the forward end of the system and rotate the barrier from the folded position to the upright position. The system may include a rotational mounting structure to which the moveable barrier is connected. The rotational mounting structure may be removably connected to the forward end of the divider. The merchandise display system may be used in conjunction with a product tray which provides for product stored in the product tray to be slid from in the product tray into the product pocket of the merchandise display system.

A high pressure press assembly along with related methods and components for the press assembly are provided. In one embodiment, a press assembly includes a first press base having one or more tie bar receiving holes extending therethrough. A second press base may also include one or more tie bar receiving holes extending therethrough. A tie bar extends between the first press base and the second press base. A tensioning assembly is operatively coupled to the tie bar to place the tie bar in tension.

A clamping apparatus includes a clamping frame, a first guide, a clamp, a linear driver, and a pressure sensor. The first guide is disposed on the clamping frame. The clamp is slideably engaged with the first guide, the clamp being configured to linearly move along the first guide to adjust a distance between the clamp and the clamping frame. The linear driver is connected to the clamp, the linear driver being configured to cause, at least in part, linear motion of the clamp. The pressure sensor is configured to sense pressure applied to an object clamped between the clamp and the clamping frame.

Devices, systems, and methods for crimping a medical device are disclosed. More specifically, the present disclosure relates to devices, systems, and methods for reducing the diameter of a collapsible heart valve prosthesis to be loaded onto a delivery device. The devices, systems, and methods using at least one funnel to crimp the heart valve prosthesis and load it onto the delivery system.

A method for forming a tool for creating a formed component includes providing a forming tool having a core and cavity with respective core and cavity shutoff bands. Core and cavity finished parting planes are determined, wherein the engagement of the core and cavity finished parting planes defines a forming cavity. Rough portions of the core and cavity shutoff bands are removed to define respective rough parting planes. The respective rough parting planes are offset by approximately 130 microns from the respective core and cavity finished parting planes. The core and cavity are semi-finished to relieve stress within the core and cavity. The core and cavity shutoff bands are fine cut so that outer surfaces of the core and cavity shutoff bands are equal to the respective finished parting planes. The engagement between the core and cavity outer surfaces is substantially free of gaps.

A product management display system for merchandising product on a shelf includes using a trackless pusher mechanism that travels along a surface on which product is placed and one or more dividers for separating product into rows. The one or more dividers may be engaged to a front rail in two different conditions, locked and unlocked. In a locked condition, the relationship between the divider and the front rail resists alteration in any direction with respect to each other. In the unlocked condition, the dividers may be freely slid laterally along the front rail, while remaining perpendicular to the front rail. The one or more dividers may lock to the front rail through the use of corresponding teeth, resilient surfaces, a locking tab, a locking bar and/or a cam.

The invention relates to an adaptor for a distal tip of a drug delivery device. The adaptor includes an inner ring having retaining means capable of exerting a radial inward force on said distal tip and of switching from a free configuration to a locked configuration, in which the radial inward force exerted on said conical distal tip limits the axial movement of the adaptor. The adaptor further includes compressing means movable axially with respect to said retaining means between a proximal position, in which said compressing means does not exert a centripetal pressure on said retaining means, and a distal position, in which centripetal pressure is exerted on said retaining means. The invention further relates to a drug delivery device comprising such an adaptor and to a method for mounting said adaptor on said drug delivery device.

Various exemplary methods and devices for actuating surgical instruments are provided. In general, a surgical device can include one or more actuation shafts configured to facilitate actuation of the device. In an exemplary embodiment, the device can include four actuation shafts, two actuation shafts to facilitate articulation of the device, one actuation shaft to facilitate opening and closing of jaws at a distal end of the device, and one actuation shaft to facilitate moving a cutting element of the device. In an exemplary embodiment, each of the one or more actuation shafts can include a distal elongate member and a proximal elongate member having a proximal end attached to a distal end of the distal elongate member. The proximal elongate member can be rigid, and the distal elongate member can be flexible.

Various embodiments of high pressure presses and related methods of manufacturing and operating such presses are described. In one embodiment, a cubic press is described having press bases with spacers disposed between adjacent press bases. Sets of two or more tie bars are also disposed between adjacent press bases. The tie bars are placed in a state of compression while the spacers are placed in a state of compression. During operation, the press bases may become displaced relative to one another such that additional tension is experience by the tie bars while the amount of compression experienced by the spacer is reduced. The tie bars exhibit a relatively small cross-sectional area as compared to the cross-sectional area of the spacer.