In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.

The invention discloses an anus cleaner, comprising a bottle body, wherein the inside of the bottle body is a hollow structure; the bottom of the bottle body is provided with a bottle bottom, and the bottle bottom is curved; the center of the bottle bottom is provided with a through hole, and a steel ball check valve is installed in the through hole; the end of the bottle body away from the bottle bottom is provided with a bottleneck, and the bottleneck is provided with threads; the bottleneck is equipped with a cleaning head; the bottom of the cleaning head is provided with threads, and the threads are provided on a mounting table; the mounting table and the bottleneck are matched and connected with the same size; the top of the mounting table is provided with a cleaning neck.

Disclosed is an irrigation system. The irrigation system includes a manual pump. The manual pump can provide pressurized liquid through a tube at an outlet.

Disclosed is an irrigation system. The irrigation system includes a manual pump and refill. The manual pump can provide pressurized liquid through a tube at an outlet.

An oral hydration system, which includes a fluid reservoir; a supply tube fluidly coupled to the reservoir at its distal end; and a mouthpiece pump molded as a single piece utilizing one pliable material and deformable along its entire length, wherein the mouthpiece pump is fluidly coupled at its distal end to a proximal end of the supply tube, wherein the mouthpiece pump or the supply tube comprises a one-way distal valve and the mouthpiece pump is sealed proximally with a proximal face in a form of a mouthpiece containing a proximal valve that seals until the pump is deformed by a user for the purpose of creating a priming and pumping action to draw fluid from the reservoir, through the supply tube and out of the mouthpiece pump to the user.

The invention provides a fluid management system (1) for providing fluid from a fluid source (20) to the body of a patient. The fluid management system (1) includes a compressible chamber (10). A fluid conduit (30) is in fluid communication with the fluid source (20) and with an interior of the compressible chamber (10). A bypass conduit (40) has an inlet end (43) in fluid communication with the fluid source (20) and an outlet end (44) for providing fluid to a trocar (70). The bypass conduit 40 passes either through or around the compressible chamber (10). A first one way valve (80) can admit fluid from the fluid conduit (30) into the interior of the compressible chamber (10). A second one way valve (90) can admit fluid within the interior of the compressible chamber (10) into the bypass conduit (40). A portion (46) of the bypass conduit (40) upstream of the second one way valve (90) is collapsible under the force of selectively applied external pressure when the compressible chamber (10) is at least partially filled with fluid from the fluid source (20), so as to selectively close off the bypass conduit (40) upstream of the second one way valve (90).

The present invention relates to an enema device comprising a delivery container arranged for accommodating an enema and an applicator nozzle for dispersing the enema, and wherein the delivery container is arranged as a hand held pump and wherein a cross-section of said delivery container has the shape of an oval. Thereby is provided a simple, inexpensive and essentially maintenance free enema device which can be used for self-administrating of an enema.

The present application discloses an ear-cover structure and an ear irrigation device. The ear-cover structure includes a cover configured with a containing space with an opening configured at a side of the containing space, a liquid collecting portion extending outwards from the bottom of the cover, and an injection port configured on the cover and communicating with the containing space. The medium collected in the containing space flows through the liquid collecting portion and is discharged from a leakage port to the external environment.

The present invention discloses a four-way complete cleansing system for the entire upper respiratory tract (upper airway) and the process of how to use this advanced system to perform a complete cleansing of the upper airway of a human. The device is equipped with two one-way valves and at least two exchangeable tips for an effective upper airway cleansing. The composition of the cleansing solution comprises a chemical compound or an herb extract or the combination having at least one of the cleansing activities against viruses, bacteria, fungi, inflammatory factors, allergens, and promoting membrane healing or immunomodulating, for the treatment and prevention of a respiratory tract disease of a human. The present invention also provides a process for cleansing the hard-to-reach upper respiratory tract, such as sinus, of a mammal to reduce the load of the pathogen, to reduce the amount of inflammatory mediators, to heal pathological changes, and collectively to treat a disease of a mammal, such as nasal allergy or the common cold. This invention also provides a new method of treating a variety of human respiratory tract diseases without adverse effects.

A trans-anal irrigation (TAI) system adapted for self-use includes an irrigation head supplied with water from a reservoir by a pump or by gravity feed. The irrigation head has either internal or external structures for releasably retaining the head in a user's rectum during the water flow portion of a TAI process. A guide member arm may be provided for manipulating the irrigation head for both insertion and removal. The irrigation head is reliably attached to the guide member arm. The guide member arm may include an integral manual pump.