The disclosed dispenser provides for controlled dispensing of a liquid. The dispenser has a housing that supports a fluid holding system, fluid delivery system, priming mechanism, and an actuation control mechanism. The priming mechanism creates and stores an actuation force, which breaks the sealed fluid delivery system and the force can be controllably released with an actuation control mechanism to dispense the liquid. The actuation control mechanism includes a plunger that slidably advances into fluid-containing cylinders from force by the priming mechanism. The actuation control mechanism further includes an actuation button that interlocks with the plunger to start and stop dispensing. Optionally, the dispenser has two cylinders and a mixing chamber for dispensing a multi-component liquid, such as an adhesive.

A fluid applicator includes a main housing extending along a longitudinal axis defined between a first end and an opposing second end. The main housing defines an applicator outlet disposed at the first end. The fluid applicator further includes a first cylinder disposed within the main housing and including a first seal for holding a first fluid. The fluid applicator further includes a second cylinder spaced apart from the first cylinder and disposed within the main housing. The second cylinder includes a second seal for holding a second fluid different from the first fluid. The fluid applicator further includes a mixing chamber housing disposed within the main housing. The fluid applicator further includes a first piercing element, a second piercing element, and a nozzle connected to the mixing chamber housing opposite to each of the first piercing element and the second piercing element

A surgical kit for providing a cryoprotective composition configured to be applied during cryotreatment of a patient includes: a first container containing a predetermined amount or volume of a biodegradable and/or bioerodible fluid agent; and a second container containing a predetermined amount or volume of a non-toxic cryoprotectant agent. The predetermined amount or volume of the of biodegradable and/or bioerodible fluid agent and the predetermined amount or volume of a non-toxic cryoprotectant agent are configured to be mixed together to form the cryoprotective composition in which a therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment and at least a portion of a body tissue proximate to the body space is viable after the cryotreatment.

An automated, and/or semi-automated, reciprocating medicament mixing and injector system, where the energy provided to transfer medicament components back and forth between containers or cartridges can be redirected to deliver the mixed medicament components. A pressurized gas source can drive the flow through a plurality of valves to mix medicament between containers. In a fully automated embodiment, a user activated button advances a magnet to power solenoid valves to control mixing, and then dispensing the medicament. In a semi-automated embodiment, a user activated button releases pressurized gas, and mixing button routes the gas through alternating valves fluidly coupled to the containers to mix the medicaments.

A pre-filled dual-chamber medical agent delivery system assembled and configured to allow delivery of a single dose of a combined therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another, such as to facilitate delivery of a reconstituted lyophilized agent to a patient.