A method for manufacturing a centralizer assembly includes reducing a diameter of a mandrel such that a turned-down region is formed in the mandrel, positioning a first stop segment in the turned-down region, and positioning a centralizer at least partially in the turned-down region, wherein the first stop segment is positioned intermediate of axial extents of the centralizer, such that the first stop segment at least partially limits a range of motion of the centralizer relative to the mandrel

An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18 Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.

Distal access aspiration guide catheter system and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A Distal access aspiration guide catheter having a proximal, medial, and distal possessing high flexibility, high resistance to kinking and a large lumen to wall thickness ratio.

The invention relates to a tool holding fixture (1) for rotationally driven tools (2), said tool holding fixture comprising a rotationally symmetrical holding body (3) which has a front clamping portion (4) having a holding opening (5) for a tool shaft (6) of the tool (2), and a rear holding portion (7) to be held in a work spindle of a machine tool. To achieve a reduced mass, a lower mass moment of inertia and at the same time high stiffness, a sleeve (11) consisting of a fiber-reinforced plastic is arranged at least in the front clamping portion (4).

The method includes a tension element, for example in the form of flat steel, that is placed on the structure or structural part and can be guided around a corner. The flat steel can also wrap as a band around the structure, in which the two ends of the flat steel are either connected to one another or are separately connected to the structure by the end anchors or intersect to produce a clamping connection. The flat steel contracts as a result of a subsequent active and controlled input of heat using a heating element and generates a permanent tensile stress and, correspondingly, a permanent prestress on the structure. The structure, as equipped, has at least one tension element as a shape memory alloy which extends along the outer side of the structure and is connected by one or more end anchors.

A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.

Embodiments of the present invention include a press base assembly, a strengthening ring for use with press bases and related methods. In one embodiment, a press base assembly includes a press base having a body that includes a piston cavity at one end. The body, at a second end opposite that of the piston cavity, may exhibit a desired geometry. A strengthening ring may be shaped, sized and configured to substantially mate with the geometry of the second end of the body and be placed thereover. For example, the geometry of the second end may be substantially circular exhibiting a particular diameter and circumference. The strengthening ring may have substantially circular internal surface sized and configured such that the strengthening ring is positioned on the second end of the body in a manner that results in an interference fit between the two components.

A centralizer assembly and method for manufacturing a centralizer assembly. The centralizer assembly includes a mandrel including a first raised region having a first diameter, and a turned-down region having a second diameter, the second diameter being smaller than the first diameter. The centralizer assembly also includes a first stop segment extending at least partially around the mandrel in the turned-down region, and a centralizer disposed at least partially in the turned-down region. The first stop segment is received between axial extents of the centralizer, to limit a range of motion of the centralizer relative to the mandrel.

A high pressure press assembly along with related methods and components for the press assembly are provided. In one embodiment, a press assembly includes a first press base having one or more tie bar receiving holes extending therethrough. A second press base may also include one or more tie bar receiving holes extending therethrough. A tie bar extends between the first press base and the second press base. A tensioning assembly is operatively coupled to the tie bar to place the tie bar in tension.

Various embodiments of high pressure presses and related methods of manufacturing and operating such presses are described. In one embodiment, a cubic press is described having press bases with spacers disposed between adjacent press bases. Sets of two or more tie bars are also disposed between adjacent press bases. The tie bars are placed in a state of compression while the spacers are placed in a state of compression. During operation, the press bases may become displaced relative to one another such that additional tension is experience by the tie bars while the amount of compression experienced by the spacer is reduced. The tie bars exhibit a relatively small cross-sectional area as compared to the cross-sectional area of the spacer.