The present disclosure relates to a system and a method for automatically measuring and assessing hemodynamics in tissue of an anatomical structure of a subject. In particular the present disclosure relates to continuously measuring and assessing hemodynamics in medical procedures using fluorescence imaging and wherein the administration of the fluorescent agent is controlled and automated. One aspect relates to a method of automatic perfusion assessment of an anatomical structure of a subject, the method comprising administration into a vein of a bolus corresponding to less than 0.005 mg ICG/kg body weight of a first fluorescence imaging agent. Another aspect relates to a system for automatic perfusion assessment of an anatomical structure during a medical procedure of a subject comprising a controllable injection pump for holding at least one first fluorescence imaging agent, the injection pump being configured for injecting a predefined amount of said first fluorescence imaging agent into the blood of the subject, wherein the system is configured for receiving and analysing a time series of fluorescence images of the tissue of said anatomical structure following the injection of the first fluorescence imaging agent, and determining at least one perfusion parameter of said anatomical structure based on said analysis.

A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).

A medical drainage stent that includes a stent body, and a proximal portion and a distal portion that are located at two ends of the stent body for connecting a first tissue wall and a second tissue wall in a juxtaposing manner. The stent body is fixed between the first tissue wall and the second tissue wall to provide a drainage channel. The proximal portion of the stent has N extension portions, where a fixed end of the extension portion is fixedly connected with an edge of a proximal end of the stent body, and the other end of the extension portion is a free end in a free state. Structures of the N extension portions at least partially protrude from the stent body in a radial direction, so that the proximal portion of the stent is fixed on the first tissue wall, where N is a positive integer.

The following describes various applications and uses for a controllably rigidizable flexible, device or sheath, Such rigidizing mechanisms can allow for a transition between a rigid state and a flexible state of a sheath. Rigidization can be applied along an entire length of a flexible sheath or along select portions of the sheath, and the rigidization can be of varying stiffness. Rigidization can be user controlled or automatically controlled using computer processes.

A balloon catheter for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen; the ballon catheter comprising: An elongated balloon; a coating layer overlying an exterior surface of the balloon wherein the coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent; and a length-control mechanism (600) which stretches and elongates the balloon during deflation, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

The present disclosure relates to the field of body lumen drainage. Specifically, the present disclosure relates to implantable medical devices for facilitating the flow of fluids and materials between adjacent body lumens. In particular, the present disclosure relates to a drainage stent which maintains an open flow passage between fused tissue layers.

Provided are a catheter device and a catheter package which are capable of preventing a bend from being formed in a catheter body.

The catheter body includes a wire state discrimination portion which discriminates a protruding state and a non-protruding state, in which the wire state discrimination portion includes a stopper which allows a transition from the protruding state to the non-protruding state, and blocks a transition from the non-protruding state to the protruding state.

A tubular indwelling device 1 is placed inside a living body lumen and defines a tubular flow path, the tubular indwelling device comprising: a skeleton part 10; a membrane part 20; and a shape retention part 30. The skeleton part 10 includes a body part 11 which can expand/contract along the radial direction of the tubular indwelling device 1. The membrane part 20 is provided along the body part 11, and includes a protruding part 22 that protrudes from a tube end part 11a so as to create a tapered shape in which a flow path cross-section area on a distal end side spaced apart from the tube end part 11a is smaller than a flow path cross-section area on a base end side which is the tube end part 11a side of the body part 11. The shape retention part 30 retains the shape of a flow outlet 23 of the protruding part 22.

The present disclosure relates to the field of body lumen drainage. Specifically, the present disclosure relates to implantable medical devices for facilitating the flow of fluids and materials between adjacent body lumens. In particular, the present disclosure relates to a drainage stent which maintains an open flow passage between fused tissue layers.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.