Devices, systems and methods are disclosed for treating or preventing a developmental disorder, such as attention-deficit hyperactivity disorder (ADHD), an autism spectrum disorder, Asperger syndrome, childhood disintegrative disorder, overactive disorder, pervasive developmental disorder. A device comprises an electrode having a contact surface for contacting an outer skin surface of a patient and a power source coupled the electrode. The power source generates and transmits an electrical impulse having a frequency of about 1 kHz to about 20 kHz through the contact surface and the outer skin surface to a nerve within the patient. The electrical impulse is sufficient to modify the behavioral disorder in the patient.

Methods, systems and apparatuses for delivering electrical or other therapy in the vicinity of the eye, comprising eyepieces having a plurality of electrodes that are placed on the eyelid. Some examples are just eyepieces having a periphery that partly surrounds the eye, other examples fully surround the eye or include a temporal portion configured to extend to the temple of the user. Some examples also include a field that covers the eye to take the form of a goggle. Numerous configurations for power supply and therapy output are discussed.

Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.

Alternating electric fields (e.g., TTFields) may be applied to a subject's body using an electrode assembly that includes a skin contact layer formed at least partially of a conductive adhesive composite. An electrode element is electrically coupled to the conductive adhesive composite. Optionally, the electrode assembly can include a layer (e.g., sheet) of anisotropic material between the electrode element and the skin contact layer. Optionally, the skin contact layer may comprise an outer adhesive layer comprising conductive adhesive composite, an inner adhesive layer comprising conductive adhesive composite, and a substrate positioned between the inner and outer adhesive layers.

Bacteria, cancer cells, fungus and other harmful cells located beneath the surface of a mammal body can be effectively destroyed by passing an electrical current through the area to be treated. Electrodes are positioned on either side of the area to be treated, for example, gums, fingers, arms, legs, feet and torso, and an electric current is caused to flow between the electrodes and through the area to be treated. The electric current will destroy the bacteria, cancer cells, fungus or other harmful cells.

A system and method for non-invasively applying electrical stimulation to target the olfactory bulb and olfactory mucosa. Current is delivered through an optimal montage of electrodes positioned on the lower forehead, nose bridge, and neck posterior for suppressing the progression of disorders or alleviating symptoms caused by olfactory dysfunction such as Alzheimer’s Disease, Parkinson’s Disease, Loss of Consciousness, etc. Electrode placements are proposed depending on application- for instance using only hair free zones for stimulation. This invention was made with government support under Grant R44NS092144 awarded by the National Institutes of Health. The government has certain rights in the invention.

A method of soft tissue treatment of a patient comprises placing an applicator onto a surface of a soft tissue, with the applicator including an RF electrode and a dielectric material having a vacuum cup and a dielectric material under the RF electrode, with the dielectric material under the electrode having an absolute value of difference between polarization factor below center of the RF electrode and below edges of the RF electrode in a range from to 0.10005 mm to 19 800 mm, and heating the soft tissue via the RF electrode, and applying vacuum into a cavity under the applicator with changing pressure value inside the cavity under the applicator compared to pressure in the room during the treatment in range from 0.01 kPa to 100 kPa.

A cage assembly can have at least one enclosure. Each enclosure can have a floor defining a floor area having a major dimension and a cover having a bottom surface. A spacing between the bottom surface of the cover and the floor can define a cage height. At least one sidewall can extend between the floor and the cover. A ratio of the cage height to the major dimension of the floor area of each enclosure of the at least one enclosure can be at least 0.70.

A method for using soft physiotherapy instrument is provided. The method comprises providing a soft physiotherapy instrument comprising a flexible sheet and a controller, applying the flexible sheet of on a user's skin, and turning on the controller and selecting a function button on the controller, inputting a current to a plurality of functional layers in the flexible sheet, and stimulating user's skin with the current.

A method of non-surgical correction of joint deformity using a therapy stimulator machine that includes a first and second handheld probe electrode; using the hand held probe electrodes with water to apply pressure to locations and wiggle the probe electrodes around the joint to stimulate directing toxic waste to the blood circulatory system of the patient.