Disclosed are electrode assemblies having at least two layers of conductive adhesive material separated by an anisotropic material and methods of using the electrode assemblies in Tumor Treating Fields (TTFields) therapy.

The present invention relates to methods and devices to consolidate memory and/or cognitive functions by monitoring brain rhythms and delivering a stimulus at an appropriate stage of sleep cycle.

A portable, battery powered apparatus (10) generates an electrical signal between electrodes (15a, 15b) to be applied to the skin of a patient for reduction or prevention of snoring or obstructive sleep apnoea. The signal comprises electrical stimulation at a frequency of 1-100 Hz and the signal comprises a stimulation free period of at least 0.5 seconds every 20 seconds, avoiding muscle fatigue when used for long periods, e.g. overnight.

The present invention relates to a stimulation electrode comprising an ionically conductive pressure sensitive adhesive composition comprising a) a (meth)acrylate resin comprising at least 10% of a (meth)acrylate monomer comprising OH-group by weight of the total weight of the (meth)acrylate resin; and b) an ionic liquid. The stimulation electrode according to the present invention is used in skin applications transferring an electrical signal to the body via skin.

Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio head-phones for concurrent delivery of TES and audible signals (e.g., music).

A skin treatment device for home use is provided herein. The device has enhanced safety features and improved operation efficiency. RF energy is delivered under strict control to a relatively small and well localized volume of the skin, avoiding excessive heating of the skin surface. Surface heating is monitored both by direct temperature measurement and by movement monitoring of the device to ensure proper use and prevent skin overheating and the pain associated therewith.

An apparatus can include a subassembly having one or more electrode elements, each electrode element having a skin-facing side and a skin-facing surface. The apparatus can further comprise a skin contact layer comprising a conductive adhesive. The skin contact layer can be coupled to the subassembly and can be disposed on the skin-facing side of the electrode elements. The conductive adhesive is electrically coupled to the electrode and configured to contact skin of a subject. At least a portion of the skin contact layer is selectively removable from the subassembly.

A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrodes, the array configured to be positioned over the subject's body with a face of the array facing the subject's body, the array including electrode elements positioned in existing electrode positions arranged around a centroid of the array; and at least one void space in the array capable of enclosing an areal footprint equivalent to at least 40% of an areal footprint of at least one existing electrode position, and superimposable on at least 40% of at least one existing electrode position by rotation of the array around the centroid.

A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrodes configured to be positioned over the subject's body with a face of the array facing the subject's body; a substrate including an adhesive layer, wherein the array of electrodes is disposed entirely on a first side of the substrate, the face of the array faces away from the substrate, the adhesive layer is on the first side of the substrate facing the same direction as the face of the array; and, when viewed from a direction perpendicular to the face of the array, a non-adhesive region is located between a pair of adjacent electrodes of the array, the non-adhesive region spanning at least 25% of a total distance between the pair of adjacent electrodes for at least one measurement measured along a straight line between the pair of adjacent electrodes.

A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: a substrate and an array of electrodes disposed on the substrate, the array configured to be positioned over the subject's body with a face of the array facing the subject's body; wherein, when viewed from a direction perpendicular to the face of the array, the substrate has at least one concave edge forming at least a portion of a boundary of the array, the at least one concave edge defines an opening between two opposing sides of the substrate, no electrodes are present in the opening, and the substrate has a substantially C-shaped, U-shaped, rounded V-shaped, or annular shaped surface.