A neuromodulation system includes a conductive element, a magnetic field generator, a power module and a computer processor. The conductive element located internal a patient's body. At least a portion of the conductive element is positioned adjacent to a target tissue. The magnetic field generator is positioned external to the patient's body. The magnetic field generator generates a time varying magnetic field for inducing stimulation of the target tissue in combination with the conductive element to produce stimulation that is larger than that which would occur in the absence of the conductive element. The power module supplies power to the magnetic field generator. The computer processor controls the time varying magnetic field provided by the magnetic field generator according to at least one set of stimulation parameters.

A magnetic-vibration and magnetoelectric therapy device, comprising an upper computer and a lower computer; the upper computer is used to send control instructions to the lower computer, and the lower computer is used to output stimulation signals acting on a human body based on the control instructions. The lower computer comprises a control unit, a magnetic vibration unit, a magnetoelectric unit and an electrical stimulation unit; the control unit is connected with the magnetic vibration unit, the magnetoelectric unit and the electrical stimulation unit respectively, the magnetic vibration unit is used to generate a vibrating magnetic field acting on a human body, the magnetoelectric unit is used to generate a vibrating rotating magnetic field acting on a human body, and the electrical stimulation unit is used to generate electrical stimulation signals acting on a human body. The device can be used to treat chronic prostatitis.

A lead introducer includes an integrated sheath/needle including a splittable sheath configured to split a into a first portion and a second portion, a needle having a length and a proximal end region, and a hub coupled to the proximal end regions of the splittable sheath and the needle and configured to split into a first portion and a second portion. The needle is permanently attached to either the first portion of the hub or the first portion of the splittable sheath (or both) so that when the hub is split into the first and second portions, the needle remains attached to the first portion of the hub or the first portion of the splittable sheath.

Provided herein is a method of blocking a nerve or neuron including applying an electrical stimulation to the nerve or neuron, wherein the electrical stimulation is of an intensity that is greater than an excitation threshold of the nerve or neuron for a length of time sufficient to produce a block of nerve conduction or neuron excitation.

Systems and techniques for wireless implantable devices, for example implantable biomedical devices employed for biomodulation. Some embodiments include a biomodulation system including a non-implantable assembly including a source for wireless power transfer and a data communications system, an implantable assembly including a power management module configured to continuously generate one or more operating voltage for the implantable assembly using wireless power transfer from the non-implantable assembly, a control module operably connected to at least one communication channel and at least one stimulation output, the control module including a processor unit to process information sensed via the at least one communication channel and, upon determining a condition exists, to generate an output to trigger the generation of a stimulus.

A system and method for delivering a medicament including a catheter configured for implantation in different target tissue sites, extending from a proximal end to a distal end, and having a sidewall which defines an internal lumen. The distal end has one or more apertures in the sidewall for the release of the medicament into the target tissue site; the system also comprises a medicament reservoir fluidly communicable with the internal lumen of each catheter, an adhesive member configured to adhere to the skin of the patient around the exit wound and having an opening therein to allow the catheters to pass through the adhesive member and a retaining member configured to be overlaid on the adhesive member and comprising a guide surface configured to receive a length of the two or more catheters and a plurality of retaining portions to retain the catheters against the guide surface.

A method of providing electrical stimulation to a patient, to treat a disorder from which the patient suffers, includes: detecting respiration of the patient with a sensor; and repeatedly administering electrical stimulations to a target site of the patient. Suitably, the repeated administration of said electrical stimulations is automatically synchronized with the respiration of the patient as detected by the sensor.

Disclosed are gastrointestinal dysfunction treatment protocols and kits for the testing, diagnosis, clinical intervention (diet, medications, temporary gastric electrical stimulation, and/or permanent gastric electrical stimulation), clinical feedback and/or associated treatment parameter adjustment for treating gastrointestinal dysfunctions in a patient. Embodiments of the present disclosure relate to how neuromodulation via gastric electrical stimulation, performed anywhere in the gastrointestinal (GI) tract, can help modulate inflammation and its resultant effects. Modulating inflammation via neuromodulation and gastric electrical stimulation enables treatment of a plurality of gastrointestinal dysfunctions.

A system for fecal propulsion includes one or more sensors, a stimulator, one or more pairs of electrodes, a controller and a programming device. The sensors detect at least one marker of colonic activity from the enteric, autonomic and/or somatic nervous system. The stimulator generates energy of a particular waveform, intensity and/or time-course to modulate targeted neural circuitry with stimulation parameters being adaptable and dynamic to accommodate the various types of modulated tissues. The electrodes deliver stimulation to the enteric, autonomic and/or somatic nervous systems to control fecal propulsion. The controller and programing device change the stimulation parameters in real-time based on sensor feedback to acutely drive the circuitry from rest to productive defecation. The stimulation waveforms can be simultaneously or sequentially delivered to condition some tissues, while modulating others. The system is adaptive and can be driven through a data analytic repository and machine learning algorithm.

Methods of preventing, treating, and/or controlling a hemorrhage in an organ of a patient include providing electrical stimulation to the arteries, veins, nerves innervating the arteries or veins, or walls of the organ. The apparatus has at least one electrode operably connected to a stimulus generator and placed in electrical communication with an artery, vein, nerve, or organ wall. An electrical stimulus generator causes an electrical stimulus to be administered to the artery, vein, nerve, or wall through the at least one electrode, where the electrical stimulus is effective for preventing, treating, and/or controlling a hemorrhage.