Devices, systems, and methods for applying pulsed energy to effectuate a physiological response in a human subject. Systems and methods disclosed herein can include, for example, a stimulus device that applies pulsed energy, such as heat, into a volume of tissue. The stimulus device can include one or more electrodes and can be affixed to the skin or implanted at a target site within the body. The systems and method can further include a monitoring device that detects at least one physiological parameter of the human subject during application of the pulsed energy, such as blood flow, oxygen delivery, muscle tension, subcutaneous or muscle temperatures, or brain activity. A control device can use the detected physiological parameter to define treatment parameters of the stimulus device such that the pulsed energy synchronizes with the measured physiological parameter to effectuate a desired response, such as reducing pain, suppressing appetite, and/or activating a hedonic response.

Systems and methods described herein include a pressure delivery component that has a pressure applicator configured to selectively apply therapeutic pressure to a treatment portion of a user body, and also includes a thermal delivery component that has a thermal applicator that is a configured to apply thermal treatment to the treatment portion. The thermal applicator may be removably disposable in operative relationship with the pressure delivery component in a use configuration of the treatment delivery component such that the thermal applicator is disposable between the treatment portion and the pressure applicator when the treatment delivery component is disposed on the treatment portion in the use configuration. Moreover, the pressure applicator is operable to apply pressure to the thermal applicator to enhance apposition of the thermal applicator to the treatment portion.

A band to be worn by a user and for securing an enclosure of a wearable neurostimulation device that stimulates one or more peripheral nerves of a user is provided. The band may include a flexible platform that bends from a first shape to a second shape. The band may include a plurality of lugs that have an engagement structure configured to mechanically engage with the enclosure when the flexible platform is in the first shape and disengage from the enclosure when the flexible platform is in the second shape. The band can further include an electrode system that has an inner side and an outer side. The inner side having at least one electrode for each nerve to be stimulated.

Provided is a switched capacitor-based electrical stimulation device which supplies a direct current (DC) power, detects a charging voltage charged in any one of a plurality of capacitors, controls the DC power supplied to a capacitor module to repeat a charging level and a resting level according to a charging pattern when the charging voltage is lower than a target voltage, and outputs an electric current to electrodes which contact a human body based on an output pattern.

The present invention relates to a method for inducing a controlled fluid transport in a central nervous system, CNS, and/or in a cerebrospinal fluid, CSF system, of a patient by electro-osmosis, EO, via two or more electrodes placed at selected locations on the patients head, comprising receiving EO information, the EO information being at least indicative of fluid transport response resulting from application of particular electric potentials and/or currents at particular electrode locations on the patient's head based on a patient-specific three-dimensional head model, receiving a fluid source location within the patient's head, selecting a set of electrode locations using the EO information and the fluid source location, placing the two or more electrodes in electrical communication with said CNS/CSF-system, each electrode being placed at one location of the selected set of electrode locations, and controlling an application of selected electric potentials and/or electric currents to said electrodes, wherein the selected electric potentials and/or electric currents is selected as electric potentials and/or electric currents associated to the selected set of electrode locations by the EO information, so as to induce a controlled fluid transport in said CNS/CSF-system.

Described herein are high-power pulsed electromagnetic field (PEMF) applicator apparatuses. These apparatuses are configured to drive multiple applicators to concurrently deliver high-power PEMF signals to tissue. The apparatuses may be further configured to wirelessly communicate with local computing device and a remote server for patient monitoring, prescription and/or device servicing.

[Problem] To provide a cosmetic mask which imparts effective stimulation to the appropriate position and has a tightening effect. [Solution] This cosmetic mask is worn on the face of a user, is able to cover at least the cheeks, and is equipped with a pair of simulators which impart electric or ultrasonic stimulation to a location corresponding to either the zygomatic muscle or masseter muscle of the user. The cosmetic mask may be equipped with a stimulator fitting unit for fitting the stimulators to a cheek position, and maybe constituted so that at least some of the stimulators are detachable. The cosmetic mask may also be equipped with a nosepiece which matches the protruding shape of the nose, a left-right fitting portion which is fitted while applying tensile force to the left and right sides of the face, and a vertical fitting portion which is fitted while applying tensile force from the lower surface of the mandible over both sides of the face to the top of the head.

The invention disclosed here relates in general to the field of medical devices. In particular, to devices and methods for improving the clinical outcome of patients suffering from cardiac dysrhythmias without cardiac arrest. This method and/or device integrates mechanical, pneumatic, acoustic and/or electrophysiologic capabilities with electrical countershock or pacing capabilities such that the probability of successful cardioversion or pacing is increased. The sequence, forces, and electrical properties of the subsystems can be computer controlled and adjusted in response to biomarker inputs.

The electrical stimulation garment includes an electrical stimulator, a flexible substrate, a plurality of electrical connectors, a plurality of electrodes and a plurality of locators. The electrical stimulation is applied to the body part by the electrical stimulator through the placement of the plurality of electrical connectors in contact with the plurality of electrodes to a prescribed area of the body part as identified by the plurality of locators.

The invention described herein provides for a portable autonomic nerve system stimulation device that may operate as an “open-loop” or “closed-loop” stimulation system and includes in some embodiments a paired therapy for a disease or condition. Embodiments of the inventive device include at least one stimulation circuit for the generation and delivery of a stimulation, at least one biological signal monitoring apparatus for monitoring a biological state of a user wearing the device, at least one controller in electrical communication with the stimulation circuit and at least one power supply for providing power to the controller and stimulation circuit. Aspects of the invention provides for a portable autonomic nerve system stimulation device which may be worn in the ear, or about the head, of a subject, patient or user.