A portable automated life-saving system, comprising one or more sensors utilized for collecting data related to a patient's current medical condition and to transmit the collected data to a main computer; a main computer adapted with suitable hardware and software to process data, received from the one or more sensors, with respect to predefined medical conditions and corresponding life-saving treatment protocols, thereby to determine an initial life-saving treatment protocol to be delivered to the patient, and accordingly to operate a main controller configured to activates corresponding life-saving devices; a main controller adapted to be operated by the main computer, for controllably activating fastening means, and for controllably activating one or more life-saving devices for delivering life-saving treatment to the patient; two or more fastening means, controllably activated by the main controller for obtaining a firm attachment of the automated life-saving system to a patient; one or more life-saving devices controllably activated by the main controller for delivering life-saving treatment to the patient; one or more batteries. The portable automated life-saving system continuously monitors the evolving medical condition of a patient, and correspondingly adapts the given treatment, namely, the operation of the one or more life-saving devices.

In one embodiment, the present invention provides a device, wherein the device comprises a skin patch, configured to attach to the skin surface of the perineum of a subject suffering from premature ejaculation, wherein the skin patch contains electrodes configured to deliver electrical impulses transcutaneously to the bulbcavernosus muscle of the subject, wherein the transcutaneously delivered electrical impulses are configured to treat premature ejaculation.

Articles and methods for non-invasively treating peripheral neuropathy via transcutaneous electrical stimulation of target nerve tissue are described. An exemplary article includes a support on which an electrode pair is positioned; a controller attached to the electrode pair via one or more leads; and a power supply connected to the controller. The article delivers electrical stimulation to the target nerve tissue via the electrode pair at a level sufficient to initiate vasodilation of vasculature within or adjacent the tissue. Meanwhile, the method includes positioning at least one electrode pair adjacent an area of skin overlying or in close proximity to the target nerve tissue and delivering electrical stimulation to the tissue via the electrode pair. The electrical stimulation is delivered at a level sufficient to initiate vasodilation of vasculature within or adjacent the tissue. An implantable system and method for treating peripheral neuropathy via percutaneous electrical stimulation are also described.

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.

A patient-worn ambulatory cardiac monitoring device for monitoring a patient during a patient activity includes at least one physiological sensor configured to detect signals indicative of cardiac activity, an activity sensor and associated circuitry configured to monitor patient movements, and a vibrational sensor configured to monitor a cardio-vibrational signal of the patient. The at least one physiological sensor can include one of an ECG sensor and a heart rate sensor. At least one processor in communication with the at least one physiological sensor, the activity sensor, and the vibrational sensor, is configured to measure, during the patient activity, at least one time interval between an ECG fiducial point in an ECG signal and a cardio-vibrational fiducial point in the cardio-vibrational signal during a cardiac cycle of the patient's heart.

Described herein are high-power pulsed electromagnetic field (PEMF) applicator apparatuses. These apparatuses are configured to drive multiple applicators to concurrently deliver high-power PEMF signals to tissue. The apparatuses may be further configured to wirelessly communicate with local computing device and a remote server for patient monitoring, prescription and/or device servicing.

A neuromodulation system includes a conductive element, a magnetic field generator, a power module and a computer processor. The conductive element located internal a patient's body. At least a portion of the conductive element is positioned adjacent to a target tissue. The magnetic field generator is positioned external to the patient's body. The magnetic field generator generates a time varying magnetic field for inducing stimulation of the target tissue in combination with the conductive element to produce stimulation that is larger than that which would occur in the absence of the conductive element. The power module supplies power to the magnetic field generator. The computer processor controls the time varying magnetic field provided by the magnetic field generator according to at least one set of stimulation parameters.

Alternating electric fields (e.g., TTFields) may be applied to a subject's body using an electrode assembly that includes a skin contact layer formed at least partially of a conductive adhesive composite. An electrode element is electrically coupled to the conductive adhesive composite. Optionally, the electrode assembly can include a layer (e.g., sheet) of anisotropic material between the electrode element and the skin contact layer. Optionally, the skin contact layer may comprise an outer adhesive layer comprising conductive adhesive composite, an inner adhesive layer comprising conductive adhesive composite, and a substrate positioned between the inner and outer adhesive layers.

This invention controls stimulation levels and cycling cadence on an FES ergometer to minimize or prevent the occurrence of spasm in spinal cord injured or other neurologically impaired patients.

A tissue stimulation device comprising: a source; a control unit; a decoupled output stage circuit connected to the source and the control unit; a signal generator connected to the input of the decoupled output stage circuit and the control unit; an analog demultiplexer connected to the output stage circuit decoupled by a PE signal and an out signal, the analog demultiplexer is connected to the control unit, and a transducer array is connected to the output of the analog demultiplexer; wherein the control unit selects the output of the analog demultiplexer that allows switching of the PE and out signals to activate the transducers in the transducer array to stimulate tissue.