A wearable device and the accompanying method for the determination of continuous pulsatile BP are described. The absolute values can be obtained in the initial phase and how a transfer function can transform the BP-signal obtain at the finger or wrist to correct BP-values corresponding to the brachial artery and at heart level. The wearable device contains an orthostatic level-correcting element, which can measure the vertical distance between heart level and finger/wrist level, where the actual measurement takes places. The wearable device may be in the form of a ring, a watch, or a bracelet. Further, the wearable device has elements for wirelessly transmitting signals to host devices such as a smart phone, tablet or other computers.

Methods, devices and machine readable programs are presented for measuring blood pressure using a device configured to guide a user regarding placement of an anatomical region of interest in relation to a sensor. The methods can include measuring, by the sensor, a pressure applied to the sensor and measuring, by the sensor, blood volume oscillations in the anatomical region of interest while pressure is being applied to the sensor by the anatomical region of interest. The methods can further include estimating, by processing circuitry (e.g, computer processor(s), memory and the like) of the device, a blood pressure value for the user from the measured pressure and the measured blood volume oscillations.

A system and method for determining cardiovascular parameters can include: receiving a plethymogram (PG) dataset, removing noise from the PG dataset, segmenting the PG dataset, extracting a set of fiducials from the PG dataset, and transforming the set of fiducials to determine the cardiovascular parameters.

The method serves to determine at least one physiological parameter of a patient. A pulse measurement signal of a pulse pressure wave propagating within the blood vessels and emanating from the heart is acquired at a pulse measurement point. A corrected pulse measurement signal is produced from the acquired pulse measurement signal by means of signal processing. The at least one physiological parameter is ascertained on the basis of the corrected pulse measurement signal. For the purposes of producing the corrected pulse measurement signal, the acquired pulse measurement signal is subjected to adaptive filtering with a dynamically adapting filter characteristic in order to compensate the influence of a reflected component of the pulse pressure wave.

Disclosed is a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure utilizing the volume clamp method. The finger cuff may comprise: a finger cavity to receive the patient's finger; a micro-laser and a detector to measure a pleth signal; a bladder mountable within the finger cavity, wherein the patient's finger received in the finger cavity abuts against the bladder; and a processor. The processor may be configured to control pressure applied by the bladder to the patient's finger based upon measuring the pleth signal received from the detector and the micro-laser to keep the pleth signal approximately constant to replicate the patient's blood pressure to implement the volume clamp method and to measure the patient's blood pressure.

The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

A device for obtaining physiological information including plethysmographs of a medical patient and detecting a condition of pneumonia. The portable pneumonia screening device may include one or more sensors configured to obtain physiological information. The pneumonia screener may provide for methods of selecting and interfaces to assist selecting a patient's age group. The screener may match a selected age group from a set of programmed threshold level of oxygen saturation, respiratory, pulse rate, or other physiological parameters to assist pneumonia diagnosis. The pneumonia screener may provide one or more visual and/or audio stimuli, such as an animation, sound or music. The visual and/or audio stimuli may indicate initialization, diagnostic in progress, completion, or other events or progress of events. In some embodiments, the visual and/or auditory stimuli may be used to soothe or intrigue the patient such that patient agitation is reduced during the screening process.

The invention relates to a method of operating a long-term blood pressure measurement device having a measurement sensor for detecting a pulse wave signal, having a measurement sensor for body current signals, having a pressure cuff for a non-invasive determination of the blood pressure, having a control and evaluation unit for determining blood pressure values, on the one hand from signals acquired by means of the pressure cuff (pressure cuff signals), and, on the other hand from a pulse wave transit time that is derived from body current signals and pulse wave signals, and having a memory for storing blood pressure values.

A method for measuring reactive hyperemia in a subject is disclosed. The method includes performing a first segmental cuff plethysmography to generate a baseline arterial compliance curve and/or a baseline pressure-area (P-A) curve, performing a second segmental cuff plethysmography to generate a hyperemic arterial compliance curve and/or a hyperemic P-A curve, and calculating an area between the baseline and the hyperemic curves. The size of the area can be used as an indication of endothelial dysfunction (ED) and ED-related diseases.

In the present invention, a pump driving circuit includes a step-up unit that steps up a first DC voltage from a power supply and outputs it as a second DC voltage, and an H bridge unit that has first and second series circuits that each include two switching elements connected in series between a high potential corresponding to the second DC voltage and a reference potential. According to a control signal from the control unit, the two switching elements of the first series circuit and the two switching elements of the second series circuit are switched on and off. A voltage generated between a first contact point between the two switching elements of the first series circuit, and a second contact point between the two switching elements of the second series circuit is used as a driving voltage for driving a pump.