A system to generate a representation of a rhythm disorder that includes identifying remote or polar sources associated with a cardiac rhythm disorder is disclosed. The system includes generated a representation based on the cardiac information signals received from the sensors by transformation of spline-sensor locations of the catheter to x-y coordinate pairs of locations. A first offset is determined resulting from a perturbation to corresponding x-y coordinate pairs of locations associated with the representation, the first offset displacing coordinate pairs of sensor locations of the representation at least one unit of displacement in a first direction. A remote source associated with a cardiac rhythm disorder is identified when activations associated with the cardiac information signals rotate in sequence at least once, or emanate centrifugally for at least a first time period, the source being identified based on the representation as displaced. A corresponding method and computer-readable medium are also disclosed.

The present disclosure discusses a devices, systems and methods for transvascular, transvenous and/or transdural access, to the brain parenchyma, subarachnoid or subdural spaces. In some embodiments, the disclosed systems and methods may be used for local drug delivery, tissue biopsy, nanofluidic or microelectronic device/component delivery/insertion/implantation, in situ imaging, ablation of abnormal brain tissue and the like. Embodiments of the present disclosure include an access catheter system for extravascular procedures in the brain having an elongate, flexible tubular body, with at least one lumen extending axially there through between a proximal end, and a distal end. The access catheter system may include a side exit port and a distal end port. Further, the access catheter system may include a selective deflector positioned within the lumen configured to deflect a procedure catheter and permit a guide catheter.

A catheter adapted or high density mapping and/or ablation of tissue surface has a distal electrode matrix having a plurality of spines arranged in parallel configuration on which a multitude of electrodes are carried in a grid formation for providing uniformity and predictability in electrode placement on the tissue surface. The matrix can be dragged against the tissue surface upon deflection (and/or release of the deflection) of the catheter. The spines generally maintain their parallel configuration and the multitude of electrodes generally maintain their predetermined relative spacing in the grid formation as the matrix is dragged across the tissue surface in providing very high density mapping signals. The spines may have free distal ends, or distal ends that are joined to form loops for maintaining the spines in parallel configuration.

This disclosure is directed to a catheter having a basket-shaped electrode assembly at the distal end of the catheter body formed from a plurality of spines with electrodes. The basket-shaped electrode assembly structural elements at the proximal and distal ends. The structural elements may maintain the spines in a desired spatial relationship with each other and/or may couple the distal ends of the spines to a pulling member. The basket-shaped electrode assembly has expanded arrangement in which the spines bow outwards and a collapsed arrangement in which the spines are arranged generally along a longitudinal axis of the catheter body

The invention relates to a hybrid intracerebral electrode comprising a narrow, elongated body intended to be implanted in the brain of a patient in order to carry out at least one multi-scale electroencephalographic exploration. Said hybrid intracerebral electrode comprises, in its active part, a plurality of first electrical contact elements forming stationary macro-contacts, and a plurality of second electrical contact elements forming movable micro-contacts. The hybrid intracerebral electrode is characterised by control means which are built into the electrode in a coupling tip integral with the body. The control means are designed to move the second electrical contact elements between a passive position in which same are retracted inside the body and an active position in which same protrude outside the body, and simultaneously to adjust the controlled projection length thereof with respect to the body of the electrode.

This disclosure is directed to a diagnostic catheter having an improved irrigation system for reducing thrombus formation. The catheter may have an irrigated electrode assembly with a plurality of spines, each with a plurality of irrigation ports to flush the device and reduce the risk of thrombus formation.

A temperature probe for monitoring temperatures of a surface of a tissue or organ within the body of a subject includes a section with a substantially two-dimensional arrangement and a plurality of temperature sensors positioned across an area defined by the substantially two-dimensional arrangement. Such an apparatus may be used in conjunction with procedures in which thermal techniques are used to diagnose a disease state or treat diseased tissue. Specifically, a temperature probe may be used to monitor temperatures across an area of a surface of a tissue or organ located close to the treated tissue to prevent subjection of the monitored tissue or organ to potentially damaging temperatures.

A method of displaying electrophysiology information includes obtaining a three-dimensional medical image of an anatomical region, registering a localization system to the model; localizing an electrophysiology catheter within the anatomical region; displaying a representation of the localization of the electrophysiology catheter on the model; and displaying image slices of the model. The image slices are selected based upon the localization of the electrophysiology catheter. For example, the image slices can pass through a user-selected localization element carried by the electrophysiology catheter. Rigid and/or non-rigid transforms can be used to register the localization system to the model. Electrophysiology data collected by the catheter can be displayed on the model and/or the image slices thereof. The three-dimensional medical image and/or the electrophysiology data can also be time-varying. In embodiments, scalar maps can also be displayed on the model.

Aspects of the present disclosure are directed to flexible high-density mapping catheters with a high-density array of mapping electrodes. These mapping catheters may be used to detect electrophysiological characteristics of tissue in contact with the electrodes, and may be used to diagnose cardiac conditions, such as cardiac arrhythmias for example.

In one embodiment, a medical system, includes a catheter to be inserted into a chamber of a heart of a living subject, and including catheter electrodes configured to contact tissue at respective locations within the chamber of the heart, a display, and processing circuitry to receive signals from the catheter, and in response to the signals assess a respective quality of contact of each of the catheter electrodes with the tissue in the heart, and render to the display respective intracardiac electrograms traces representing electrical activity in the tissue that is sensed by the catheter electrodes at the respective locations, while modifying a visual feature of at least some of the traces responsively to the respective quality of contact of the catheter electrodes with the tissue of the heart at the respective locations.