This patent application refers to oral health composition and preparation process thereof, suitable for direct administration into the oral cavity by specialists or otherwise, wherein the formulations have a wide action spectrum due to self-activation and continuous formation of reactive oxygen, with no need for external activation by light, chemicals or electricity, except for air oxygen, said oral health compositions acting through the synergistic action of air oxygen with octa-carboxy or tetra-carboxy (metal-phthalocyanines) being functional dyes capable of promoting self-activation and continuous production of reactive oxygen in the presence of molecular oxygen in suitable, safe and effective amounts over odor-making substances, microorganisms and over coagulation/healing mechanisms, among other properties of interest for maintenance of oral health, which may be used directly by the patient or by a professional.

The present invention relates to the use of methylene bis-benzotriazolyl tetramethylbutylphenol, optionally in combination with tris-biphenyl triazine, to reduce fabric staining of a sunscreen or daily care composition, wherein the sunscreen or daily care composition comprises (i) at least one particulate UV-f liter; and/or (ii) at least one oil soluble UV-A filter, wherein the at least one oil soluble UV-A filter is present in an amount of at most 3% by weight, based on the total weight of the sunscreen or daily care composition; and/or (iii) at least one water soluble UV filter. Furthermore, the present invention relates to the use of methylene bis-benzotriazolyl tetramethylbutylphenol, optionally in combination with tris-biphenyl triazine, to facilitate the washability of such sunscreen or daily care compositions from textiles.

Provided are compounds of formula (Ia), (Ib) and (IIa), and pharmaceutically acceptable salts thereof. Additionally provided are compositions and pharmaceutical compositions comprising the compounds, therapeutic methods using same for modulating (e.g., inhibiting) CREB binding protein (CBP)/β-catenin mediated signaling in treating a condition, disease or disorder (e.g., fibrosis, cancer, neurological conditions, metabolic disorders (e.g., diabetes, etc.), and skin conditions (dermatitis, psoriasis, scarring, alopecia, etc.) mediated by aberrant CBP/β-catenin signaling, and cosmetic methods for treating skin conditions (e.g., aging, etc.). Additionally, provided are methods for enhancing vaccine efficacy using the compounds and compositions. Further provided are methods for efficiently synthesizing a clinical grade drug, comprising use, in a penultimate, or last reaction step under GMP conditions, of an intermediate 2-propynyl-compound to form a clinical grade isoxazole derivative (e.g., via 3+2 cycloaddition).

An aerosol cosmetic exhibits an improved feeling of use while having high UV blocking properties. An aerosol cosmetic is filled up as a bulk solution together with a propellant in a pressure-resistant container and includes ethyl alcohol that is a main dispersion medium, an organic ultraviolet absorber, and an ester oil. The organic ultraviolet absorber includes an organic ultraviolet absorber that is solid at room temperature. The solid organic ultraviolet absorber is dissolved in the ester oil.

The present invention relates to the use of the compounds (A) corresponding to formula

##STR00001##

wherein
R.sup.1 is hydrogen; a linear or branched C.sub.1-C.sub.30 aliphatic hydrocarbon residue comprising 0, 1, 2 or 3 double bonds;
R.sup.2 independently from each other are hydrogen; methyl; ethyl; —OH; —COOR.sup.4; —CH.sub.2—OH; and —CH.sub.2—COOR.sup.4;
R.sup.4 is hydrogen; or a linear or branched C.sub.1-C.sub.30 aliphatic hydrocarbon residue comprising 0, 1, 2 or 3 double bonds;
R.sup.3 independently from each other are hydrogen; methyl; ethyl; —OH; —COOR.sup.6; —CH.sub.2—OH; and —CH.sub.2—COOR.sup.5;
R.sup.5 is hydrogen; or a linear or branched C.sub.1-C.sub.30 aliphatic hydrocarbon residue comprising 0, 1, 2 or 3 double bonds;
n is at least 0,1 on average;
m1 and m2 independently from each other are 0; or 1;
with the proviso, that at least one of the radicals R.sup.1, R.sup.4 or R.sup.5 represent a linear or branched C.sub.1-C.sub.30 aliphatic hydrocarbon residue comprising 0, 1, 2 or 3 double bonds,
as solubilizing agent for organic UV filters (B) selected from
(B1) benzophenone derivatives;
(B2) hydroxyphenyl triazine derivatives; and
(B3) trianilino-s-triazine derivatives.

The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.

A subject matter of the present invention is a composition comprising: a) at least multilayer spherical composite particles comprising i) a core comprising at least one material A having a refractive index ranging from 1.3 to 1.8; and ii) at least one layer covering said core, comprising at least one material B having a refractive index ranging from 1.9 to 3.1; and iii) optionally at least one second layer covering the material B, comprising at least one material C having a refractive index ranging from 1.3 to 1.8; said composite particles being present in an amount less than 28.0% by weight relative to the total weight of the composition; and b) at least one UV-screening agent.

This composition is for topical use and is more particularly intended for the photoprotection of the skin and/or hair against ultraviolet (UV) radiation.

The present disclosure is directed to stabilizing compositions comprising a mixture of three or more ultraviolet filters. The disclosed compositions are useful for stabilizing the color and the fragrance of formulations, including cosmetic formulations and household products.

The present invention provides a polymerizable compound that reduces, for example, the likelihood of crystals precipitating in a polymerizable composition including the polymerizable compound and enables the polymerizable composition to have high preservation stability and a polymerizable composition including the polymerizable compound which reduces the likelihood of inconsistencies being formed in a film-like polymer produced by polymerizing the polymerizable composition. Also provided are a polymer-produced by polymerizing the polymerizable composition and an optically anisotropic body including the polymer. The present invention provides the compound represented by General Formula (I), a composition including the compound, a polymer produced by polymerizing the composition, and an optically anisotropic body including the polymer.

A non-irritation, non-blurring, photostable ophthalmic sunscreen composition contains at least one of the following: bemotrizinol; bisoctrizole; tris-biphenyl triazine; and/or octyl methoxycinnamate. A liquid vehicle base is then a remainder of the solution by weight. The composition is an artificial tear formulation or an ophthalmic suspension or ointment. The composition may include at least one inorganic and/or at least one organic active ingredient. The inorganic active ingredients may include, but not be limited to zinc oxide, titanium dioxide, iron oxide, zirconium oxide, and cerium oxide. The organic active ingredients may include, but not be limited to dioxybenzone, octinoxate, octisalate, homosalate, avobenzone, octocrylene, para-aminobenzoic acid, cinoxate, methyl anthranilate, octocrylene, padimate O, ensulizole, sulisobenzone, trolamine salicylate, and ecamsule.