Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the catheter are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.

A kit is disclosed for accurately loading a small volume dose of a medication within a syringe and for delivering the small volume dose of the medication at a treatment site. The kit generally includes a loading and delivery system in accordance herewith, a syringe, and a medication. The loading and delivery system includes a syringe delivery ring and a syringe loading guide, which may be used for example, to administer a small volume dose of a medication at the end of an ocular surgery.

Disclosed is an injection device including a body for receiving a syringe, a firing mechanism including a reaction component, a plunger configured to be axially displaced in a forward direction relative to the reaction component, and a drive spring located between the reaction component and the plunger for driving the plunger forwards upon activation of the injection device, wherein the reaction component provides a reaction surface for the drive spring. The device further includes a locking mechanism for locking the reaction component in a first axial position within the body, the locking mechanism being configured to release the reaction component upon a predefined forward movement of the plunger thereby allowing the reaction component to be driven in a rearward axial direction by the drive spring until it impacts against the body or a component secured to the body to thereby emit an audible indication of an end of dose.

A fluid displacement and pressurization device which provides both a substantial amount of thread engagement as well as provides for single hand control for all operational manipulations including maintaining a set fill volume, rapid filling and displacement, and pressurization and retention of evacuation positioning during balloon depressurization. The device allows for the use of one hand to not only transition the device from micro-movement control to macro-movement control, but also regarding rotating, pushing or pulling the handle of the plunger.

The present invention may provide a medical syringe comprising: a cylinder including a stopper protruding inward; and a plunger disposed inside the cylinder so as to move back and forth in a first direction, wherein the plunger includes a plurality of protrusions, and the plurality of protrusions are arranged at intervals along the longitudinal direction of the plunger, and based on the first direction, any one of the stopper or the plurality of protrusions is arranged so as to be selectively overlapped according to the rotation of the plunger.

A needleless injector having a drive end with an energy source for propelling a quantity of fluid out a distal opening of a barrel of an ampule, wherein the drive end is provided with a cam and a follower for resetting the spring to enable multiple injections and deliveries of a discrete quantities of fluids out the barrel. The drive end can further include a carrier having a stepped barrel for sequentially moving a different surface of a different step adjacent the plunger of the ampule upon each reset of the spring.

An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial includes a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial. The adapter includes a needle assembly having a first tip and a second tip, with the needle assembly disposed within the housing and at least partially supported by a needle holder. The needle assembly is movable relative to the housing from an initial position in which the first and second tip are isolated from the cartridge and vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, establishing fluid communication therebetween. The needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing.

Devices used to deflate an inflatable hemostasis device are disclosed. The devices may be configured to deflate the inflatable hemostasis device in staged increments over a period of time. The devices may include a barrel member and a plunger member comprising an insert configured to couple with a retention ring of the barrel to restrict a retraction distance of the plunger member.

Flush syringe assemblies are described herein. Such flush syringe assembly may include a barrel including a side wall defining a chamber, an open proximal end, a distal end having a distal wall with an elongate tip extending distally therefrom having a passageway therethrough in fluid communication with said chamber. A collar may be mounted on the distal wall of the barrel and surrounding the elongate tip. A disinfectant-loaded swab may be disposed in the collar. The flush syringe assembly may also include a removable cap.

A non-slip dose delivery mechanism includes a housing, a non-rotating piston rod, a nut, a piston rod guide, a driver, a ratchet and a brake. The non-rotating piston rod has a threaded outer surface. The nut includes an inner surface in threaded engagement with the threaded outer surface of the non-rotating piston rod. The nut is configured to rotate and translate axially in a proximal direction relative to the non-rotating piston rod during dose setting. The piston rod guide is rotationally fixed relative to the housing and is configured to prevent rotation of the piston rod. The driver includes an inner surface and an outer surface, the inner surface being in a rotationally fixed engagement with the nut. The ratchet is rotationally fixed to relative to the housing. The brake is positioned between the nut and the ratchet.