The present disclosure relates to a drive subassembly for a drug delivery device, the drive subassembly comprising a proximal housing part comprising a body portion and a closure portion configured as separate parts adapted to be coupled to each other, the closure portion comprising an end face and a guide rod extending from the end face in a distal direction, the guide rod adapted to be inserted into a drive spring; and a plunger, wherein the body portion comprises a profiled slot adapted to engage a plunger boss of the plunger to impede movement of the plunger in the distal direction unless the plunger is rotated to move the plunger boss out of the profiled slot. The disclosure furthermore relates to a proximal housing part for a drug delivery device, to a method for assembling the drive subassembly and to a method for assembling the drug delivery device.

A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a finger flange coupled to the syringe flange. Moreover, the system includes a stopper member disposed in the syringe interior. In addition, the system includes a plunger ratchet member coupled to the stopper member. The system also includes a plunger tube disposed coaxially around at least a portion of the plunger ratchet member and operatively coupled thereto.

The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end.

The disclosure relates to a syringe, comprising a barrel and a plunger, wherein at least a part of said plunger is longitudinally slidably received in the barrel, wherein the plunger comprises a portion that is provided with at least one series of interspaced plunger formations, wherein the barrel is provided with a corresponding barrel formation for consecutively engaging successive ones of the plunger formations, wherein the syringe is arranged such as to be brought from a first state in which the barrel formation successively engages the plunger formations during slidable displacement of the plunger within the barrel, into a second state in which the barrel formation is held in a position spaced away from the plunger portion that comprises the plunger formations.

A syringe assembly includes (i) a syringe with a cylindrical body, luer tip at a first end, finger grip at a second end and a cannula extending from the luer tip into the cylindrical body, and (ii) a plunger unit having an adapter portion, receiving cavity, finger grip and piston. A channel extends the length of the adapter portion to receive the cannula in one end and a variety of connectors, valves and/or syringes in a second end. The end of the channel accessible in the receiving cavity mates with or engages any number of commercially available valves, connectors and/or syringes while the luer tip similarly connects to any number of valves, catheters, connectors, etc., depending on the task being undertaken with the syringe assembly.

The bearing component comprises a contact surface inside a periphery, which surrounds a centre, and a coupling feature arranged inside the periphery for rotatably engaging a component of a piston rod perpendicular to the contact surface. The coupling feature includes at least one flexible feature extending from the periphery towards the centre, and the flexible feature is arranged to be deflected towards the periphery by a force exerted on the flexible feature in a direction towards the contact surface and deflected towards the centre by a force exerted on the flexible feature in the opposite direction. The flexible feature may have a sloping surface facilitating assembly and preventing disassembly in combination with a further component of the piston rod. The component of the piston rod may be a lead screw, and the piston rod may be used in a drug delivery device.

An injection device is disclosed comprising a plunger for expressing medicament from a syringe and a delivery mechanism arranged in use to provide a forward biasing force to urge the plunger from a first rearward position to a second forward position to express a dose from the syringe. A latch arrangement is provided that releasably holds the plunger against the force of the de livery mechanism. The latch arrangement comprising at least two resilient segments which define opposing sections of an aperture within which a rearward end of the plunger is retained in the rearward position. A trigger is provided for releasing the plunger in use, the trigger being arranged to outwardly deflect at least one of the resilient segments such that the aperture is expanded to release the rearward end of the plunger. A method of manufacturing the injection device is also enclosed.

An autoinjection device (10′) for expelling a dose of drug is described. A housing (300) movably holds a power unit (400, 500, 550, 700) configured for driving the piston of a held container (100), the power unit comprising: a) a plunger (500) comprising a retaining geometry (515), b) a drive spring (550) arranged in a tensed state wherein a first end portion of the drive spring (550) provides a distally directed force on the plunger (500), and c) a power base (400) operably coupled to the drive spring (550) and the plunger (500), the power base (400) grounding a second end portion of the drive spring (550), wherein, in a pre-firing state of the autoinjector, a retaining element (410, 415) of the power base (400) releasably engages the retaining geometry (515) of the plunger to retain the plunger against the force of the drive spring (550), wherein the autoinjection device (10′) further defines a user operable trigger element (700) cooperating with the retaining element (410, 415) to maintain retaining engagement with the retaining geometry (515) of the plunger until triggering, and further defines an electronic module (80′) comprising a sensor (850, 851) configured to sense the shift of position of the power base (400) as it moves upon triggering.

An injection device is disclosed including a housing assembly defining a pair of ramps and adapted to hold a medicament cartridge. A driver is adapted to advance the piston within the cartridge. A plunger having a pair of arms is moveable between a retracted position and an advanced position. Each of the arms are engageable with a respective one of the ramps as the plunger is advanced. A braking mechanism may include braking members on the arms and braking tracks proximate the ramps. Excessive force exerted on the plunger may flex the arms and engage the braking members with the braking tracks. The plunger arms may be connected together by a material bridge that biases the plunger arms apart from each other. The arms may include detents that engage to prevent the arms from moving due to the biasing force of the material bridge when the arms are in the fully retracted position.

A dual chamber syringe, comprising a syringe barrel having a forward end, a rearward end and at least one bypass protrusion arranged along the longitudinal extent of the syringe barrel; a finger grip element coupled to the rearward end of the syringe barrel, the finger grip comprises at least one protrusion extending radially inwardly from an inner surface thereof; a plunger rod operatively coupled with the finger grip element; a guiding track is formed on the plunger rod and comprises a helical track portion and a longitudinal track portion; and wherein upon relative displacement of the plunger rod and said finger grip element, the at least one protrusion is guided along the guiding track.