In some examples, electrical stimulation is delivered to a patient such that selective termination of the stimulation causes a therapeutic effect in the patient after termination of the electrical stimulation to the patient. The electrical stimulation may be insufficient to produce a desired therapeutic effect in the patient during stimulation, but sufficient to induce a post-stimulation desired therapeutic effect following termination of the stimulation. In some examples, the electrical stimulation may be sub-threshold electrical stimulation. In some examples, the desired therapeutic effect may alleviate bladder dysfunction, bowel dysfunction, or other disorders. The stimulation may be selectively terminated in response to one or more therapy trigger events to induce the post-stimulation therapeutic effect.

A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.

An intra-pelvic fundus vesicae support disposed at the outer fundus vesicae position and fixing the front end to the pelvic pecten pubis position to lift internal organs. An injection channel is provided inside an intra-pelvic fundus vesicae support structure, and a screw hole is formed at an input hole, so that the support can be connected to an in-vitro device. According to the intra-pelvic fundus vesicae support, a tomoscan three-dimensional modeling technology is used to generate a model file which completely conforms to physiological shapes of the pelvic pecten pubis and the outer fundus vesicae and the spatial form of the abdominal cavity of a typical person, and the intra-pelvic fundus vesicae support of a frame structure and medical material quality is obtained using 3-D printing technologies. Before a surgery is conducted, a virtual reality technology is used to simulate and verify a surgical safety scheme.

This disclosure describes methods, systems, and devices configured to determine a timing of a future bladder related event of a patient. For example, a system includes processing circuitry configured to identify a timing of a plurality of bladder related events of a patient, determine, based on the timing of the plurality of bladder related events of the patient, a probability to experience a bladder related event function for the patient, the probability to experience a bladder related event function indicating a probability that the patient will experience a bladder related event at an elapsed time after a previous bladder related event, predict, based on the probability to experience a bladder related event function, a timing of a future bladder related event, and control delivery of a therapy to the patient based on the predicted timing of the future bladder related event.

Systems and methods for the treatment of bladder conditions using direct electrical pacing are provided. The systems and methods generally apply high-frequency pacing stimuli directly to the bladder wall, from one or more of the inner and outer bladder surfaces.

The present disclosure provides ablation catheter systems and electrode assemblies and electrode baskets for use in the ablation catheter systems that include an interlinked diamond configuration formed from a plurality of strut assemblies. Each strut assembly includes one or more struts that are manufactured from a thermoplastic or metallic material. The interlinked diamond configuration facilitates reducing an overall length of the electrode assembly. Further, the interlinked diamond configuration facilitates expanding and contracting the struts simultaneously and by the same amount.

Systems and methods for treating bladder and/or bowel dysfunction of a patient includes a stimulation element implanted to stimulate one or more target sites, and a sensor to sense sensing at least one parameter of the patient indicative of a potential bladder or bowel dysfunction event. In some examples, stimulation energy is applied to an anatomical structure of the patient as a function of the sensed parameter, for example to address the potential bladder or bowel dysfunction event.

An ablation instrument comprises an elongate shaft having a cannula channel and a scope channel, and an electrode disposed in the cannula channel. The electrode is slidable between a first position in which a distal end of the electrode is contained within the cannula channel, and a second position in which the distal end of the electrode extends out of a distal opening of the cannula channel. The ablation instrument further comprises a distal head coupled to the elongate shaft and configured for contacting solid tissue.

The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.

A temporary medical electrical lead includes a connector pin and a single conductor coil. The coil being close-wound and having no turns of the coil distal portion being mechanically coupled together. The coil distal portion translates a force of no greater than 0.1 lb.sub.f (0.4 N) when strained 400%.