The present disclosure is directed to a system and method modulating targeted neural and non-neural tissue of a nervous system for the treatment of head-and-face pain. Electrical stimulation is delivered transcutaneously to the treatment site that modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting nervous signaling and the perception of pain.

Systems and methods for controlling energy delivered to an area of tissue during a treatment procedure are provided. The system includes a device for delivering energy to the area of tissue; an energy generator for generating and supplying energy to the device; and a controller for controlling an amount of energy generated by the energy generator and delivered to the area of tissue by the device. Controlling the amount of energy delivered to the area of tissue alters a primary zone of the area of tissue to a first level, alters a secondary zone to a second level, alters a tertiary zone to a third level, or a combination thereof, where the first level, the second level, the third level, or a combination thereof is predetermined, and where a coverage area of the primary zone, the secondary zone, the tertiary zone, or a combination thereof is also predetermined.

One or more systems, computer-implemented methods and/or computer program products to facilitate a process to produce a specified electrical output are provided. A system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise an inverse modeling component that can generate an entity-based model and can determine updated one or more electrostatics parameters based on feedback relative to application of an electrical stimulation therapy employing an initial one or more electrostatics parameters on the entity. In one or more embodiments, a configuration component can determine the initial one or more electrostatics parameters based on an initial physical-based model based on an ideal entity, the configuration component can generate an initial physical-based model based on an ideal entity, and/or the inverse modeling component can update the initial model to generate the entity-based model.

The present disclosure relates to methods, devices and systems used for the treatment of neurological disorders via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, minimally invasive methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infratrochlear, auriculotermporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal, infraorbital, and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein. Systems and devices configured for therapeutic stimulation of the branches of the trigeminal nerves, such as the superficial trigeminal nerve, and their methods of application are also described.

Systems and methods for using sensory threshold and/or adaptation for neurological therapy screening and/or parameter selection. A representative method for establishing a treatment regimen for a patient includes: in response to a first indication of a characteristic of the patient's sensory response to an electrical stimulus, providing a second indication indicating suitability of an electrical signal for delivery to the patient to address a patient condition, wherein the electrical signal has a frequency in a frequency range from 1.2 kHz to 100 kHz.

Articles and methods for non-invasively treating peripheral neuropathy via transcutaneous electrical stimulation of target nerve tissue are described. An exemplary article includes a support on which an electrode pair is positioned; a controller attached to the electrode pair via one or more leads; and a power supply connected to the controller. The article delivers electrical stimulation to the target nerve tissue via the electrode pair at a level sufficient to initiate vasodilation of vasculature within or adjacent the tissue. Meanwhile, the method includes positioning at least one electrode pair adjacent an area of skin overlying or in close proximity to the target nerve tissue and delivering electrical stimulation to the tissue via the electrode pair. The electrical stimulation is delivered at a level sufficient to initiate vasodilation of vasculature within or adjacent the tissue. An implantable system and method for treating peripheral neuropathy via percutaneous electrical stimulation are also described.

Neuromodulation is achieved by administering variable pulse electric or magnetic stimulation to a patient in need thereof. The neuromodulation can inhibit or enhance neuronal-synaptic transmission or muscle-synaptic transmission between neuron and muscle fibers The variable pulse electric or magnetic stimulation varies based on one or more mean and standard deviations of biological variables. Biological variables include heart rate variability, EEG variability, EMG variability and the frequency of activity measured in the spinal cord. The invention also includes devices that deliver the variable electric or magnetic pulses to the patient. Magnetic stimulation can be provided by electromagnetic or solid magnet stimulation.

Systems, methods, and devices for treating chronic pains effectively are disclosed. The system is based on the use of randomly generated non-pulsed waveform between a frequency of 5 Hz to 2 KHz. The waveforms generated have characteristics which are pre-defined or based on the input and feedback provided by the patient and/or by the clinician, at the same time conforming to certain safety rules and precautions ensuring patient safety. This disclosure also describes a novel approach of implementing a secure memory stick which can be used to exchange data securely between one device and another device where device could be the device mentioned earlier, an off-line server, or a PC.

A system, method, and apparatus for treating a medical condition by applying transcutaneous electrical stimulation to a target peripheral nerve of a subject. Electrical stimulation is applied to the peripheral nerve via a stimulation electrode pattern under closed-loop control in which EMG responses are monitored and used to adjust stimulation parameters. In response to detecting an unacceptable recording, electrical stimulation is applied to the peripheral nerve under open-loop control.

A method and apparatus are disclosed for providing therapeutic electric current to a treatment site of a patient. The steps of the method comprise generating a first and second signal having a frequency difference between 1 Hz and 300 Hz, wherein each signal has a frequency of at least 1 KHz and are amplified by Class D switching amplifiers, minimizing the DC component of the first and second signals using balanced amplifiers; operatively coupling a first electrode of at least one pair of electrodes to a patient's body on or beneath a first epidermal or mucous membrane surface; operatively coupling a second electrode of at least one pair of electrodes to a patient's body on or beneath a second epidermal or mucous membrane surface; forming a therapeutic signal configured to reduce pain at a treatment site by simultaneously sending a first signal from the first electrode to the second electrode and sending a second signal from a second electrode to the first electrode, and then simultaneously sending the first signal from the second electrode back to the first electrode and the second signal from the first electrode back to the second electrode, wherein the first and second signals are linearly independent off phase alternating current signals; and adjusting the therapeutic signal utilizing a feedback system based on impedance changes within the patient's body.