A wearable device for detecting and/or measuring physiological information from a subject includes a housing, at least one optical emitter supported by the housing, at least one optical detector supported by the housing, a first light guide supported by the housing, a second light guide supported by the housing, a motion sensor supported by the housing, and a processor supported by the housing. The processor is configured to calculate footsteps, distinguish footsteps from heart beats, and to remove footstep motion artifacts from signals produced by the at least one optical detector. Also, the processor is configured to process signals produced by the at least one optical detector to determine subject heart rate and to produce integrity data about the subject heart rate. The process is further configured to generate a multiplexed output serial data string comprising the subject heart rate and the integrity data.

A system for monitoring vital signs, configured to be used in conjunction with a computerized mobile device, the system including: a cover sensor assembly adapted to be operably engaged with the computerized mobile device, the cover sensor assembly having integrated therein at least one physiological sensor; a physiological data acquisition module configured to generate a physiological parameter measurement descriptive of a physical stimulus received by the at least one physiological sensor; and a validation module configured to control a validity status of the physiological parameter measurement.

An apparatus for estimating blood pressure according to an example embodiment of the present disclosure includes: a pulse wave sensor configured to measure a pulse wave signal from an object; and a processor configured to obtain a first feature and a heart rate based on the pulse wave signal, estimate a mean arterial pressure (MAP) based on the first feature and the heart rate, and estimate a first blood pressure based on the MAP and a pulse pressure (PP).

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

A vital signs monitoring system, the system including: (a) an ear device including: a curved body adapted to a shape of an ear, an upper end, a lower end, two opposite facing sides, a first side adapted to be proximal a skull and a second side adapted to be proximal an earlobe, the ear device including: (i) a temperature sensor adapted to sense a body temperature from a depression between a lower, jawbone and skull; and (b) a control system, including a processor and a memory, configured and operable to control operation of the ear device, to collect signals received from at least one sensor including the temperature sensor, to process the signals to provide medically significant results.

An ear-wearable electronic device has a shell with an outer surface. A mounting void goes through the outer surface of the shell and exposes an internal volume of the shell. The mounting void is located at an ear-contacting region of the shell. The ear-wearable device includes a photoplethysmography sensor assembly having an optical transmission structure mounted in the mounting void and having a distal end exposed proximate the outer surface. The distal end of the optical transmission structure conforms to the outer surface of the shell at the ear-contacting region. The distal end is in contact with ear tissue of a user of the ear-wearable electronic device during use.

Provided herein is a non-invasive device for measuring glucose levels (i.e., concentration) in a subject, preferably a human subject. The present invention relates to a wearable device, a kit and a method thereof for measuring blood glucose concentrations/levels. The non-invasive devices of the present invention can be used as wearable devices such as a smart band, ring, bracelet, watch and the like to monitor the blood glucose levels in diabetics without discomfort and stress due to finger pricks by measuring bio-impedance data.

An ear-worn device includes a speaker, an optical emitter, an optical detector, a processor, and a housing configured to be positioned within an ear of a subject, wherein the housing encloses the speaker, optical emitter, optical detector, and processor. The housing includes at least one window that exposes the optical emitter and optical detector to the ear of the subject, and the housing includes at least one aperture through which sound from the speaker can pass. Light transmissive material is located between the optical emitter and the at least one window and is configured to deliver light emitted from the optical emitter to an ear region of the subject at one or more predetermined locations. Light transmissive material is positioned between the optical detector and the at least one window and is configured to collect light external to the housing and deliver the collected light to the optical detector.

An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information indicates a non-distress stats and notifies a second set of contact when the opioid monitoring information indicates an overdose event. The notification can be a phone call or text message to a specified person, emergency personnel, or first responders, and can include the location of the smart mobile device. The smart mobile device can also include the location of the nearest treatment center having emergency medication used in treating opioid overdose, such as naloxone.

A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material.