An expandable substantially spherical structure for deployment in a blood vessel or other body lumen, comprising: an open frame formed out of a closed loop of filament and configured to assume (i) a collapsed configuration in the form of a substantially two-dimensional elongated loop structure so as to facilitate insertion into the blood vessel or other body lumen, and (ii) an expanded configuration in the form of a three-dimensional substantially spherical structure so as to facilitate retention at a site in the blood vessel or other body lumen; and a flow-restricting face carried by the open frame; wherein the open frame is configured so as to permit substantially normal flow therethrough when the open frame is in its expanded configuration, and further wherein the flow-restricting face is configured so as to restrict flow therethrough.

An aneurysm bridging device can be placed in the neurovasculature of a patient by advancing the aneurysm bridging device in a small-diameter configuration a delivery catheter to a target region within the neurovasculature and securing the distal region of the aneurysm bridging device to the neurovasculature. While the distal region of the aneurysm bridging device is secured to the neurovasculature, the proximal region of the aneurysm bridging device can be advanced to permit the aneurysm bridging device to expand from the small-diameter configuration and to deform and twist in a central region of the aneurysm bridging device. The proximal region of the aneurysm bridging device can be secured within the neurovasculature to maintain the central region of the aneurysm bridging device in a deformed state.

Systems for treating an aneurysm in a cerebral vessel and methods of use are described. In one embodiment, the system includes an elongate tubular member having a lumen, an expandable stent, and a delivery device. The expandable stent has a constrained state that is configured for delivery through the lumen of the elongate tubular member, and an expanded state configured for placement within the cerebral vessel adjacent the aneurysm. The delivery device includes an elongate member and a self-expandable portion. The proximal end of the self-expandable portion is coupled to the elongate member at or near the distal end of the elongate member. The self-expandable portion of the delivery device includes a tubular mesh structure having a constrained state and an expanded state. The stent is engaged (e.g., mechanical, frictional, or intermeshing) with the self-expandable portion of the delivery device.

Medical filament delivery apparatus includes a feed chamber to which can be fed filamentary material from a store of filamentary material. The apparatus is designed to feed filamentary material through a catheter into a patient, for example into an aneurysm. The apparatus includes a feed tube assembly having a feed tube with a slot at its distal end. A distal end of the filamentary material can be held within the slot to ensure accurate positioning of the distal end of the filamentary material into the drive assembly. The apparatus provides for severing of the distal end of the filamentary material once the feed tube assembly has been inserted into the drive assembly, thereby ensuring reliable positioning of the filamentary material into the drive assembly. More delicate filamentary material can be handled compared to prior art arrangements.

This invention is an intrasacular aneurysm occlusion device with a proximal stent which is expanded to a globular shape within an aneurysm sac and then compressed into a bowl shape which covers the aneurysm neck. The device further comprises embolic members and/or embolic material which is inserted into a distal portion of the aneurysm sac. The proximal stent component covers the aneurysm neck so as to reduce blood flow into the aneurysm sac and the accumulated embolic members and/or embolic material in the distal portion of the aneurysm sac keeps the proximal stent in place.

A system for removing a thrombus. The system includes an expandable device that maintains axially fixed engagement with the thrombus. The expandable device applies a first force to the thrombus according to surrounding vessel size. The expandable device applies a second force to the thrombus according to an increased vessel size to maintain axially fixed engagement.

In some embodiments, an apparatus includes a catheter having a catheter body, a light emitter disposed at a distal end of the catheter body, and a fluid conduit coupleable to a source of fluid. The fluid conduit configured to discharge fluid from the source via the conduit and out a distal end of the catheter body. A spacing member is disposed at the distal end of the catheter body and can be moved between a collapsed configuration and an expanded configuration. In the expanded configuration, the spacing member is disposed about the light emitter. The spacing member is at least partially transmissive and/or transflective of light emitted from the light emitter. The apparatus configured to be inserted at least partially into a body lumen, to discharge fluid into the body lumen, and to emit light from the light emitter to illuminate an interior wall of the body lumen.

Disclosed are coating compositions, processes, and designs for endowing vascular devices with thromboresistant and endothelializing properties. Also disclosed are designs of vascular devices used as aneurysm treating devices for assisting in the delivery, packing, and maintenance of embolization coils within an aneurysm, particularly a neurovascular aneurysm.

A cerebral aneurysm stent (1) of the present invention comprises a hollow tubular main body (10) and a coil support (20) integrally formed with the main body (10) at one end of the main body (10) in the longitudinal direction, wherein the coil support (20) comprises a closed structure (21) with respect to the radially inner side of the cerebral aneurysm stent (1), the closed structure (21) being located at an outer end portion of the cerebral aneurysm stent (1) in the longitudinal direction.

This invention is an intrasacular aneurysm occlusion device with a proximal stent which is expanded to a globular shape within an aneurysm sac and then compressed into a bowl shape which covers the aneurysm neck. The device further comprises embolic members and/or embolic material which is inserted into a distal portion of the aneurysm sac. The proximal stent component covers the aneurysm neck so as to reduce blood flow into the aneurysm sac and the accumulated embolic members and/or embolic material in the distal portion of the aneurysm sac keeps the proximal stent in place.