An example includes a capacitor case sealed to retain electrolyte, at least one anode disposed in the capacitor case, the at least one anode comprising a sintered portion disposed on a substrate, an anode conductor coupled to the substrate in electrical communication with the sintered portion, the anode conductor sealingly extending through the capacitor case to an anode terminal disposed on the exterior of the capacitor case with the anode terminal in electrical communication with the sintered portion, a second electrode disposed in the capacitor case, a separator disposed between the second electrode and the anode and a second electrode terminal disposed on an exterior of the capacitor case and in electrical communication with the second electrode, with the anode terminal and the second electrode terminal electrically isolated from one another.

A method of treating hypertension in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to a target tissue location within the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein the duty cycle is a ratio of T3 to T4, each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes, and the electroacupuncture device comprises a central electrode of a first polarity and an annular electrode of a second polarity and that is spaced apart from the central electrode; and 2) applying, by the electroacupuncture device, the stimulation sessions to the target tissue location by way of the central electrode and the annular electrode in accordance with the duty cycle.

An implantable electroacupuncture device (IEAD) treats Parkinson's disease or Essential Tremor through application of stimulation pulses applied to at least one of the acupoints on the chorea line. The IEAD includes an hermetically-sealed implantable electroacupuncture (EA) device and a conduit extending therefrom. At least one electrode is located on the outside of the housing. At least one electrode is located at an opening formed through the conduit. The housing contains a primary power source and pulse generation circuitry. A sensor wirelessly senses externally-generated operating commands, such as ON, OFF and AMPLITUDE. The pulse generation circuitry generates stimulation pulses. The stimulation pulses are applied to the specified acupoint or nerve through the electrodes in accordance with a specified stimulation regimen.

This document provides an apparatus including a sintered electrode, a second electrode and a separator material arranged in a capacitive stack. A conductive interconnect couples the sintered electrode and the second electrode. Embodiments include a clip interconnect. In some embodiments, the interconnect includes a comb-shaped connector. In some embodiments, the interconnect includes a wire snaked between adjacent sintered substrates.

Devices, systems, and techniques are described for adjusting therapy parameters defining electrical stimulation therapy. An example system includes a stimulation generator comprising a voltage stack configured to provide a stack voltage based on a multiplier of a battery voltage and processing circuitry. The processing circuitry receives a first set of parameter values that use a first stack voltage of the voltage stack to provide a first electrical stimulation defining a first therapy. The processing circuitry also determines, based on a second stack voltage lower than the first stack voltage, a second set of parameter values that define a second electrical stimulation, the second set of parameters defining a lower amplitude of electrical stimulation. Additionally, the processing circuitry controls the stimulation generator to deliver the second electrical stimulation according to the second set of parameter values using the second stack voltage of the voltage stack.

A method comprises generating, by an implantable stimulator, stimulation sessions at a duty cycle that is less than 0.05 and applying, by the implantable stimulator, the stimulation sessions to a patient. The duty cycle is a ratio of T3 to T4. Each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes.

Treatment systems, devices, articles, and associated methods of operation for treating open wounds are disclosed herein. In one embodiment, a method includes applying a first material and a second material to be in contact with a surface of the open wound having a water content at the surface and applying a voltage differential to the first and second materials, thereby producing hydrogen peroxide (H2O2) at the surface via an electrochemical reaction between oxygen (O2) in air and water (H2O) in the water content at the surface. The voltage differential is calibrated to correspond to a concentration of the produced hydrogen peroxide in the water content effective in reducing or preventing a bacterial infection at the surface of the open wound.

An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff. The cuff has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.

A method is provided for manufacturing an electrolytic capacitor for an implantable cardioverter defibrillator. The method includes forming an ester material by adding at least one acid to a glycol, and quenching the ester material for a determined period. The method also includes adding an ammonium based material to the ester material after the ester material is quenched, and adding an additional acid after adding the ammonium based material to form an electrolytic material for the electrolytic capacitor.

An illustrative method of treating cardiovascular disease in a patient may include 1) generating, by an implantable stimulator, stimulation sessions, wherein the implantable stimulator comprises a central electrode of a first polarity centrally located on a first surface of a housing of the implantable stimulator and an annular electrode of a second polarity and that is spaced apart from the central electrode; and 2) applying, by the implantable stimulator, the stimulation sessions by way of the central electrode and the annular electrode to a location, within the patient, that is associated with the cardiovascular disease.