An injection device kit for the self-administration of an injection of solution that includes a body portion configured for engagement with a cartridge containing the solution and an injection needle where the body portion includes an injection component having an actuation mechanism for inserting the injection needle of the cartridge and for injecting the solution in the cartridge and a safety mechanism on the body portion and configured to prevent injection unless released.

A dispensing device (102) is provided to dispense a designated amount of material on every dose delivery operation. The dispensing device (102) includes a thumb pad (202) and a cam drum (204) that is coupled to the thumb pad (202). The thumb pad (202) is configured to be pulled out towards a proximal end (104) of the dispensing device (102) for setting a dose of a material to be dispensed out and to be pushed in towards a distal end (106) of the dispensing device (102) for delivering the dose. The cam drum (204) includes at least one linear cam profile (402) and at least one helical cam profile (404) that are disposed on a surface of the cam drum (204). The thumb pad (202) is configured to ride on the linear cam profile (402) when setting the dose and on the helical cam profile (404) when delivering the dose.

Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.

1. A drug delivery device for delivering a plurality of fixed doses of a medicament, wherein the drug delivery device comprises a needle magazine with a plurality of needle assemblies, a needle positioning mechanism, a drive mechanism for delivering a fixed dose of the plurality of fixed doses, in response to activation, an activation mechanism for activating the drive mechanism comprising a movable shield (110, 310), wherein the shield (110, 310) is adapted to activate the drive mechanism, in response moving the shield to the proximal position. The drug delivery device further comprises a drop lock mechanism comprising a non-blocking state and a blocking state.

A drug delivery device (100, 300) for delivering a plurality of fixed doses, comprising a drive mechanism with a prestrained drive spring (108) for sequentially expelling the plurality of fixed doses, and an activation mechanism comprising an axially movable activation assembly (110, 310) for activating the drive mechanism to expel a fixed dose, and user operable for activation as a first user operation. The device further comprises a double dose prevention mechanism adapted to shift from a non-blocking to a blocking state after the first user operation of activating the activation mechanism, and adapted to shift from the blocking to the nonblocking state, in response to the second user operation of operating the unlocking structure.

Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the catheter are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.

An incremental syringe is provided and includes a syringe barrel, a finger grip disposed at the proximal end of the syringe barrel, a tab disposed inside the syringe barrel, and a plunger body having detents, wherein the detents are configured to interact with the tab to provide audible and tactile feedback to a user when the plunger body is pushed through the syringe barrel in a distal direction.

A plunger for a syringe may include a plunger head for fluid dense limiting a fluid chamber of the syringe, and a piston rod fixed to the plunger head. The piston rod may be formed by longitudinally extending axial webs that have an outwardly radial extension from the longitudinal axis and lead into a common crossing section. A free activation edge, which radially protrudes the radial extension may be provided on the piston rod and engageable with a vibration activator of a hollow body of the syringe to emit an acoustic signal. A swinging arm body may be arranged between two axial webs and couple the activation edge with the crossing section such that in case of a vibration activation in an axial direction the swinging arm body has a radial swinging arm length between the activation edge and the crossing section of at least 40% of the radial extension.

A dispenser for dispensing a metered amount of a liquid comprises a body having sidewalls defining a hollow interior and an opening at a forward end of the body, a cartridge having a reservoir adapted to contain a liquid and an outlet at the forward end of the cartridge, the cartridge being sized and shaped to be positioned in the hollow interior of the body so that the outlet is aligned with the opening in the body. A plunger is positionable in the reservoir and slidable within the reservoir, and a metering unit comprises a plunger advancement mechanism that can cause the plunger to slide within the reservoir, the metering unit causing the plunger advancement mechanism to advance the plunger a predetermined amount. The metering unit is configured to cause advancement the plunger in the reservoir to apply pressure on the liquid in the reservoir and cause a droplet of the liquid to be dispensed through the outlet. The dispenser produces a droplet of from about 0.5 l to about 10.0 l. In one version, a droplet to droplet consistency of 0.2 l. In one version, the metering unit provides feedback to a user when the plunger has been advanced the predetermined distance.

The present invention relates to drug delivery device and a and method of manufacturing a drug delivery device with a housing having a proximal end and a distal end, a cartridge adapted to accommodate a drug, a cartridge retaining member adapted to retain the cartridge, the cartridge retaining member being secured to the housing, and a spring washer being arranged within the housing so as to exerting a force on the cartridge and securing the cartridge against movement with respect to the cartridge retaining member and against movement with respect to the housing.