A safety housing based implant/medicament injecting system. System includes a needle assembly prefilled implant/medicament for injection and an injecting needle/cannula, a housing for accommodating the needle assembly under usual bias inside said housing, a plunger means having a plunger rod configured for stage wise forward motion including an initial injecting plunger forward motion with the needle assembly within the housing to first engage the needle assembly with the housing and subsequent continuing injecting plunger forward motion independent of the needle assembly for injecting of the implant/medicament, and post injecting return of the needle assembly secured inside said housing blocking any subsequent use thereof.

A drive subassembly for a drug delivery device includes a housing element, a drive member, an energy member configured to provide energy to induce a torque onto the drive member tending to rotate the drive member in a first rotational direction, wherein the drive subassembly has a first and a second locked state. In the first locked state, a first rotation-locking mechanism prevents a movement of the drive member in the first rotational direction induced by the energy member. In the second locked state, a second rotation-locking mechanism prevents a rotation of the drive member in the first rotational direction induced by the energy member and an axial-locking mechanism prevents an axial movement of the drive member. The drive subassembly is configured to be switched from the second locked state into the first locked state by releasing the axial-locking mechanism and moving the drive member in an axial direction.

A pain-reducing injection apparatus to enhance the safety, efficacy, and efficiency of injection procedures which utilize topical pain-reducing measures. Apparatuses and methods of use provide pain reduction through thermal cooling of an injection region or vibrating the region or both, and optionally include safety shielding and lockout features.

A system for injecting includes a cartridge body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the cartridge body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the cartridge body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

Vented syringes are described herein. A vented syringe includes a syringe body and a plunger body. The syringe body defines a syringe cavity. The plunger body is at least partially disposed within the syringe cavity. The plunger body includes an air intake channel defined within the plunger body. The vented syringe further includes a plunger seal that is sealingly engaged with the syringe cavity to cooperatively define a syringe volume. The vented syringe further includes a one-way valve in fluid communication with the air intake channel and the syringe volume, wherein the one-way valve is configured to prevent fluid flow from the syringe volume to the air intake channel and permit fluid flow from the air intake channel to the syringe volume.

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially penetrated into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber; and an energy-storing member operatively coupled between the stopper member and the syringe body, the energy-storing member configured to facilitate retraction of the stopper member relative to the syringe body.

A drug delivery device includes a housing defining a shell and an inner volume, a cassette, a door coupled to the housing, a drive mechanism, and a latching assembly. The cassette is removably disposed within the inner volume and is adapted to contain a drug to be administered to a user. The door at least partially encloses the inner volume of the housing and includes a first end defining a latching portion. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the drug out the cassette. The latching assembly is coupled to the drive mechanism and includes a first end and a second end. Upon actuating the drive mechanism, the drive mechanism causes the latching assembly to engage the latching portion of the door to secure the door to the housing.

A container for delivering a medicament to a target location includes a housing having a proximal end and a distal end, the housing including a cap locking tab at the distal end, and a vial containing the medicament. The container includes a plunger slidable within the vial from a proximal end to a distal end of the vial to dispel the medicament, an injection member associated with the distal end of the vial, such that the medicament dispelled from the vial passes through the injection member to the target location, and a slidable interaction member associated with the distal end of the vial configured to slide with the vial. An interaction between the slidable interaction member and the cap locking tab causes the cap locking tab to bias outward, and placement of a safety cap on the container after use locks the safety cap onto the container via an interaction with the cap locking tab.

A safety syringe has at least two angled lock extensions on opposing sides of a plunger shaft. A plunger tip integral with the shaft has at least a pair of locking lugs. A syringe barrel has a needle assembly housing end securing the needle assembly in place for injections. The needle assembly has a needle secured in a needle housing and at least two locking ledges formed as an integral part. The end cap further comprises an opening sized to receive the shaft to fit and move back and forth, and at least two locking edges. The locking edges engage with the angled lock extensions to lock the plunger in place when fully withdrawn. The locking ledges on the needle housing engage with the locking lugs when the plunger tip is pushed into the needle housing, so as to use to retract the needle into the barrel.

A barrel adapter for a syringe having a barrel and plunger. The adapter comprises a barrel tip and a needle retraction mechanism having a needle subassembly with a needle and a lumen, actuator subassembly, and biasing member. The needle subassembly moves from an injection to a retracted position within the barrel tip. The actuator subassembly includes a retainer connected to the barrel tip, a stylet held in a stylet disc, and a prong passing into the retainer. The stylet slides within the needle lumen and is spaced from the needle tip in the injection position. The biasing member biases the NOM from the retainer. A locking arrangement compresses the biasing member when locked and releases the biasing member when actuated by depression of the plunger, which moves the prong against the retainer. The biasing member moves the needle and stylet from the injection position to the retracted position when released.