A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.

A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.

A swinging bucket centrifuge (1) comprises a rotor (10) with at least one mounting end and at least one bucket (20) mounted to the at least one mounting end of the rotor (10). Therein, the at least one bucket (20) is mounted to the at least one mounting end of the rotor (10) by at least one clevis pin (30) held in a clevis (13) so that the bucket (20) is pivotable about the clevis pin (30).

Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.

A device and a method for reducing wind resistance power of a large geotechnical centrifuge are provided. A semicircular tube cylindrical cooling device is installed between an internal side of a high-speed rotor system and a cylindrical shell. A serpentine top semicircular tube cooling plate is provided right above a hanging basket, and return helium gas inlet holes are opened at a center of the top semicircular tube cooling plate. A helium gas in a helium gas storage tank passes through helium gas outlets on the helium gas inlet pipes, and enters a centrifuge chamber from a bottom sealing plate. The helium gas is used to replace air in the centrifuge chamber to reduce the wind resistance power and corresponding energy consumption. No vacuuming is required, so sealing requirements are lower. Heat dissipation equipment is placed inside the centrifuge chamber, and a helium gas circulation wind duct is added to improve heat exchange coefficient and heat dissipation effect. A special vibration isolation gasket is used, in such a manner that the vibration transmitted to the top bearing system support device by the main shaft is separated from the centrifuge chamber, thereby avoiding resonance of the centrifuge chamber and the main shaft, and ensuring safety of the centrifuge chamber. The present invention is more economical when operating at an acceleration of below 1500 g, and can maintain the temperature below 45° C.

A device and a method for reducing wind resistance power of a large geotechnical centrifuge are provided. A semicircular tube cylindrical cooling device is installed between an internal side of a high-speed rotor system and a cylindrical shell. A serpentine top semicircular tube cooling plate is provided right above a hanging basket, and return helium gas inlet holes are opened at a center of the top semicircular tube cooling plate. A helium gas in a helium gas storage tank passes through helium gas outlets on the helium gas inlet pipes, and enters a centrifuge chamber from a bottom sealing plate. The helium gas is used to replace air in the centrifuge chamber to reduce the wind resistance power and corresponding energy consumption. No vacuuming is required, so sealing requirements are lower. Heat dissipation equipment is placed inside the centrifuge chamber, and a helium gas circulation wind duct is added to improve heat exchange coefficient and heat dissipation effect. A special vibration isolation gasket is used, in such a manner that the vibration transmitted to the top bearing system support device by the main shaft is separated from the centrifuge chamber, thereby avoiding resonance of the centrifuge chamber and the main shaft, and ensuring safety of the centrifuge chamber. The present invention is more economical when operating at an acceleration of below 1500 g, and can maintain the temperature below 45° C.

An apparatus for facilitating particle separation by density includes a separator having an inner surface surrounding a rotation axis and defining a particle path from an input end to an axially spaced output end. The inner surface includes a plurality of axially spaced dividers having respective inner positions, defining at least in part respective axially spaced retainers for collecting particles during rotation of the separator. The retainers each include at least one fluid inlet for fluidizing particles in the retainer during operation. The dividers include a first pair of adjacent dividers and a second pair of adjacent dividers, the first pair nearer the input end than the second pair, wherein a first divider slope of the first pair is greater than a second divider slope of the second pair and wherein each of the first and second divider slopes is zero or positive. Other systems, apparatuses and methods are disclosed.

A liner for a filter sub-assembly has a wall having an innermost surface that bounds a cavity extending between opposing first and second ends of the liner. The wall has a deflected portion extending into the cavity and delimiting an opening. The liner may be used in a rotor of a filter assembly.

The embodiments disclosed herein generally relate to systems, devices and methods for the fractionation, isolation, extraction and processing of the adipose supernatant layer of a bone marrow aspirate. In particular, the various embodiments relate to systems, devices, and methods of obtaining, utilizing, and processing the adipose supernatant layer of a bone marrow aspirate as a source of mesenchymal stem cells.

The embodiments disclosed herein generally relate to systems, devices and methods for the fractionation, isolation, extraction and processing of the adipose supernatant layer of a bone marrow aspirate. In particular, the various embodiments relate to systems, devices, and methods of obtaining, utilizing, and processing the adipose supernatant layer of a bone marrow aspirate as a source of mesenchymal stem cells.