A neural event process, including receiving a neural response signal, decomposing the signal using at least one wavelet, differentiating phase data of the wavelets and the response signal to determine maxima and minima of the phase data and the signal, and processing the maxima and minima to determine peaks representing neural events.

Example systems and techniques for denervation, for example, renal denervation. In some examples, a processor determines one or more tissue characteristics of tissue proximate a target nerve and a blood vessel. The processor may generate, based on the one or more tissue characteristics, an estimated volume of influence of denervation therapy delivered by a therapy delivery device disposed within the blood vessel. The processor may generate a graphical user interface including a graphical representation of the tissue proximate the target nerve and the blood vessel and a graphical representation of the estimated volume of influence.

Methods of performing neural experiments on neuron-bearing living (NBL) organisms that include tracking movement of one or more NBL organisms via at least one first imaging objective and simultaneously collecting neural activity data via at least one second imaging objective. In some embodiments, the at least one first imaging objective is positioned along a first optical microscope light path and the at least one second imaging objective is positioned along a second optical microscope light path. In some embodiments, the first optical microscope light path is one of an inverted light path and an upright light path, and the second optical microscope light path is the other of the inverted light path and the upright light path. Various related methods, hardware, and software are also disclosed.

The exemplified methods and systems provide a phase space volumetric object in which the dynamics of a complex, quasi-periodic system, such as the electrical conduction patterns of the heart, or other biophysical-acquired signals of other organs, are represented as an image of a three dimensional volume having both a volumetric structure (e.g., a three dimensional structure) and a color map to which features can be extracted that are indicative the presence and/or absence of pathologies, e.g., ischemia relating to significant coronary arterial disease (CAD). In some embodiments, the phase space volumetric object can be assessed to extract topographic and geometric parameters that are used in models that determine indications of presence or non-presence of significant coronary artery disease.

Systems, devices, and methods for neurostimulation using a combination of implantable and external devices to treat pain are disclosed.

A method for measuring eye tracking in a patient and capturing ocular biometric identifying information from the patient may involve: displaying a video to the patient on a stimulus screen of an eye tracking and biometric identification system; tracking movement of the patient's eyes during display of the video via an eye tracking camera of the eye tracking and biometric identification system; capturing ocular biometric identifying information from the patient with an ocular biometric capture device of the eye tracking and biometric identification system; generating, with a computer processor of the eye tracking and biometric identification system, a score representing an ability of the patient's eyes to track the video; and confirming, with the computer processor, an identity of the patient, based on the captured ocular biometric identifying information.

Assemblies, systems, and methods are directed at a neuromonitoring bone drill bit. The assembly may include a surgical bone drill bit, a neuromonitoring connection in electrical communication with the drill bit, and a shield extending over a distal end of the drill bit. The shield may be configured to withdraw proximally as the drill bit is advanced into a subject's bone. The assembly may be connected to a surgical drill and used in a surgical spinal procedure. In operation, the assembly may be advanced to a subject's bone at a surgical site and the drill bit may rotate into the subject's bone. In response, the shield may engage the bone and the drill bit may be advanced with respect to the shield. The shield may electrically insulate tissue from electrical current passing through the drill bit as it is inserted at the surgical site.

A method to evaluate an electrochemical skin conductance (ESC) of a user body using a measurement device, the measurement device including a pair of electrodes including an anode and a cathode, a direct voltage source, a measurement resistor, control circuitry configured to set the electrical resistance value of the measurement resistor and to set the value of the direct voltage, wherein the method includes, by the control circuitry pre-stabilizing during a pre-stabilizing period, measuring during a measurement period following the pre-stabilization period.

In one embodiment, one or more computer-readable non-transitory storage media embody software that is operable when executed to determine, based on cardiac-activity data, a shift in sympathovagal balance (SVB) during the period of time; obtain an emotional-state characteristic the emotional-state characteristic being based on brain-wave activity data; and determine, based on the SVB shift and the emotional-state characteristic, an estimate of an emotional state of the user during the period of time.

A sensing and stimulation system includes a central hub, and a plurality of flexible arms extending from the central hub. Each of the arms includes at least one electrode and at least one sensor. Each of the arms is configured to perform sensing and stimulation including electrically stimulating biological material, and sensing biological responses and changes. The system includes a port configured to be alternatively connected to a remote control module for wireless operation of the system and a leaded connector for wired operation of the system.