Devices and methods for draining excess lymph fluid are disclosed. The device can be fixed to the blood vessel adjacent to the thoracic duct. The device can have a port for withdrawing lymph fluid exiting the thoracic duct. The device can have a cannula and/or subcutaneous port to draw the lymph fluid away from the thoracic duct and reduce hemostatic pressure in the lymphatic system.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

A diagnostic cassette includes a substrate, to physically and electrically connect the product to a computing device, a reservoir defined within the substrate to receive a fluid sample for processing by the diagnostic cassette, a reagent to react with the fluid sample deposited in the reservoir to form a solution to enable processing of the fluid sample by the diagnostic cassette, a channel to direct the solution, and a sensor to measure a number of parameters of the solution passing through the channel. A method for measuring microfluidic samples includes receiving, in a reservoir, a fluid sample to be measured, combining the fluid sample with a reagent to create a solution, moving the solution through a channel, and measuring the solution, using sensors, as the solution passes through the channel.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

Disclosed are devices, systems and methods for neural signal detection of immune responses. In some aspects, a system includes a processing unit: a receiving unit configured to receive at least one sensor signal from a wearable sensor, where the wearable sensor is configured to detect at least one neural signal of a patient; and a tangible non-transitory computer readable medium having instructions configured to cause the processing unit to automatically receive a data signal from the receiving unit, automatically detect an immune response based at least in part on the data signal, automatically create a notification based at least in part on the immune response, and automatically present the notification to a user of the system.

Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.

Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

The method involves using a digital badge device worn on the chest of a user to visually convey personal attributes to others in line of sight. It begins by configuring the badge device to communicate wirelessly with the user's mobile device. Next, a personal attribute of the user is determined based on input from the user or device-captured data. This attribute could relate to the user's affiliation, emotional state, physical activity, and more. Finally, a pre-defined color and/or symbol code representing the determined attribute is displayed on the badge device's screen for others to see. This provides an easily interpretable visual cue to communicate specific personal attributes to different users. By employing this method, the badge wearer can convey information about themselves without the need for verbal communication. The method offers a convenient and efficient way to signal personal attributes in situations where direct interaction may be limited or impractical.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

A system and method for collecting symptomatic data to screen for a targeted disease. Testing hardware incorporates a plurality of testing units with corresponding indicators that can be altered to indicate whether a symptom is present or not. The resulting data from the testing use can then be analyzed to determine the likelihood of presence of a disease.