Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification.

Systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position are provided. In some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and may include a plurality of ports.

Disclosed are a heart rate module and an electronic device for collecting heart rate, the heart rate module includes a substrate, and a first light wave emitting unit, a second light wave emitting unit, a first optical sensor chip, and a second optical sensor chip provided on the substrate; the substrate is also provided thereon with an isolation grating wall separating the first light wave emitting unit, the second light wave emitting unit, the first optical sensor chip, and the second optical sensor chip from each other; the isolation grating wall together with the substrate enclose respectively a first accommodating cavity for accommodating the first light wave emitting unit, a second accommodating cavity for accommodating the second light wave emitting unit, a third accommodating cavity for accommodating the first optical sensor chip, and a fourth accommodating cavity for accommodating the second optical sensor chip.

There is described a method for calculating a patient-specific hemodynamic parameter. The method comprises measuring at least one pressure measurement in an artery using an intravascular pressure measurement device, and taking at least one medical image of the artery from a medical imaging instrument, the at least one medical image of the artery being synchronous with the at least one pressure measurement. Both the pressure measurement and the medical image are fed to a computing system to calculate a flow from the at least one medical image, to calculate parameters of the artery from at least two artery pressure drops and corresponding flow components, and based on the flow and the parameters of the artery, to calculate a patient-specific hemodynamic parameter or a plurality thereof.

The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

A method for monitoring a blood glucose level of an individual comprises the steps of receiving (S1) a first glucose value, which has been measured in a body fluid of the individual other than the individual's blood, the first glucose value representing the blood glucose level of the individual with a first delay; receiving (S6) speech of the individual; analyzing (S7) the individual's speech; and determining (S8) a supplementary glucose value, which represents the blood glucose level of the individual with a shorter delay than the first delay; wherein the determination of the supplementary glucose value is based on the analyzing of the individual's speech.

This disclosure relates to a glucose-sensing electrode including a nanoporous metal layer and an electrolyte ion-blocking layer formed over the nanoporous metal layer. The nanoporous metal layer is capable of oxidizing both glucose and maltose without an enzyme specific to glucose in the glucose-sensing electrode. The electrolyte ion-blocking layer is configured to inhibit Na.sup.+, K.sup.+, Ca.sup.2+, Cl.sup.−, PO.sub.4.sup.3− and CO.sub.3.sup.2− from diffusing toward the nanoporous metal layer such that there is a substantial discontinuity of a combined concentration of Na.sup.+, K.sup.+, Ca.sup.2+, Cl.sup.−, PO.sub.4.sup.3− and CO.sub.3.sup.2− between over and below the electrolyte ion-blocking layer.

A method is provided. The method is implemented by a mapping engine stored as program code on a memory and executed by a processor. The method include subdividing an anatomical mesh of a part of an anatomical structure to one or more other meshes of the anatomical structure. The one or more other meshes are more granular than the anatomical mesh. The method includes interpolating local activation time values and velocity values for the one or more other meshes and tracing a path of velocity vectors on the one or more other meshes in accordance with the interpolation of the local activation time values and velocity values. The method also includes projecting the path on the anatomical mesh to provide an enhanced visualization of the anatomical structure.

A method, system, and/or apparatus for automatically monitoring for possible infection or other physical health concerns, such as from Covid-19. The method or implementing software application uses or relies upon location information available on the mobile device from any source, such as cell phone usage and/or other device applications. The method and system automatically uses and/or learns user location and activity patterns and determines and infection risk or illness-based deviation that can be communicated as a warning to community members.

Wrist-worn devices and methods for measuring blood oxygen saturation using a wrist-worn device compute blood oxygen saturation by processing an output signal from one or more photodetectors indicative of absorption of light by a finger interfaced with the one or more photodetectors. A method includes transmitting a first wavelength light into a finger from a first light emitter mounted to a wrist band of the wrist-worn device. A second wavelength light is transmitted into the finger from a second light emitter mounted to the wrist band. An output signal indicative of absorption by the finger of the first wavelength light and the second wavelength light is generated by one or more photodetectors interfaced with the finger and disposed on a housing of the wrist-worn device. The output signal is processed with a processor disposed in the housing to compute blood oxygen saturation.