Systems and methods provide automated parameter assurance features and results for consumables used in bioprocessing and particularly for purifying, filtering, harvesting and collecting bioprocessing fluids. Consumables having these features are sized, shaped, configured and constructed to interface with and be a component of such a bioprocessing system that includes a multi-use component or device with which it operatively engages such as by docking, engagement with a connector or other approach that allows for insertion and removal of the consumable. The consumable may be a component having a single-use life or a limited life. Each consumable has a median by which information, which can include use limits and specifications, is associated with that specific consumable, and those limits and specifications are communicated to the multi-use component which indicates any inappropriateness for use with the multi-use component.

Parallel membrane elements are arranged in parallel within a pressure vessel. A sealing body is disposed within the pressure vessel and is compressed against an inner surface of the pressure vessel to provide a leak-right seal in between a feed gas side of the sealing body and a non-permeate side of the sealing body. The sealing body may be slid within the pressure vessel without damaging the sealing body and in all cases without requiring mechanical assistance.

Disclosed herein are apparatus and methods for filtering a fluid including a filter module assembly coupled to a manifold. The manifold may include a manifold inlet in fluid communication with a source of feed liquid, an outlet in fluid communication with header of the filter module assembly, a fluid passageway in fluid communication with the manifold inlet, a source of gas, and the outlet, a second fluid passageway in fluid communication with the header and the first fluid passageway and a second manifold outlet vertically displaced from the first manifold outlet and in fluid communication between the first fluid passageway and the second fluid passageway.

The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

A tangential flow filtration manifold takes a modular form for interconnection in a manifolded arrangement for aggregating a total filtration area of the aggregate filter (membrane) surface. A plurality of modular TFF cassette filters may be or stacked on the TFF manifold such that it allows the number of interconnected filters, as well as the membrane surface area within each cassette, to be readily reconfigured. A single output, or filtrate connection on the TFF manifold simplifies fluidic plumbing connections for directing and gathering the filtrate (permeate) produced as output.

A desalination system, including a membrane distillation portion, a solar power concentration portion, and a thermal vapor compression portion operationally connected to the membrane distillation portion and to the solar power concentration portion. The membrane distillation portion includes a first vessel having a first portion and a second portion separated by a hydrophobic membrane operationally connected therebetween and oriented to pass water from the first portion to the second portion, wherein the hydrophobic membrane further comprises a hydrophilic membrane and an air blocking layer connected to the hydrophilic membrane and disposed in the first portion, a vacuum gap adjacent the hydrophobic membrane and disposed in the second portion, a first fluid inlet and a first fluid outlet operationally connected to the first portion, and a second fluid inlet and a second fluid outlet operationally connected to the second portion. The solar power concentration portion includes a pump having a pump outlet and a pump inlet operationally connected to a water line and to the vacuum gap, a linear Fresnel mirror collector for collecting and focusing sunlight, and an outlet line operationally connected to the pump outlet and positioned to receive focused sunlight from linear Fresnel mirror collector. The thermal vapor compression portion includes an ejector having an ejector inlet portion and an ejector outlet portion, wherein the ejector inlet portion is operationally connected to the outlet line and to the vacuum gap, a second vessel fluidically connected to the outlet portion and further including a heat exchanger operationally connected to the ejector outlet portion and to a water pipe, a feed spray operationally connected to the second outlet and positioned to spray into the heat exchanger, and a collection portion for receiving concentrated feed spray. The heat exchanger receives desalinated water from the ejector and from the feed spray. The water line carries desalinated water from the heat exchanger. The first outlet passes concentrated brine, and the first inlet receives feed water to be desalinated.

A modular header for a filtration module assembly is provided. The modular header includes a main body, a first liquid passageway and a second liquid passageway extending through the main body, and a gas passageway extending through the main body. The gas passageway has a first open end formed at a first side surface of the main body and an opposing second open end formed at a second side surface of the main body. An auxiliary adapter is secured to the main body at at least one of the first and second open ends of the gas passageway.

Parallel membrane elements are arranged in parallel within a pressure vessel. A sealing body is disposed within the pressure vessel and is compressed against an inner surface of the pressure vessel to provide a leak-right seal in between a feed gas side of the sealing body and a non-permeate side of the sealing body. The sealing body may be slid within the pressure vessel without damaging the sealing body and in all cases without requiring mechanical assistance.

The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

An electrodialysis unit 8 comprises a plurality of cathodes 68, a plurality of anodes 70 and a plurality of membranes 71; wherein the cathodes 68 and anodes 70 are arranged alternately in an electrode stack, with membranes 71 in between each cathode 68 and anode 70; and wherein the cathode 68 and the anode 70 are each formed of a single conductive plate such that both surfaces of the cathode plates and anode plates enclosed within the electrode stack are, in use, in conductive contact with the water being treated.