A device for separating a gas, such as air, into components, includes a plurality of modules, each module having one or more polymeric membranes capable of gas separation. A set of valves, pipes, and manifolds together arrange the modules in one of two possible configurations. In a first configuration, the modules are arranged in parallel. In a second configuration, the modules are divided into two groups which are arranged in series. The device can be switched from parallel to series, or from series to parallel, simply by changing the positions of a small number of valves, typically three valves. The device can therefore produce gas either of higher purity, or moderate purity, depending on the settings of the valves. The device also includes improved structures for connecting the modules to inlet and outlet manifolds, and also includes devices for temporarily isolating one or more modules from the system.

Disclosed herein are membrane separator modules. The membrane separator module includes a plurality of hollow fibers arranged as an annular shaped bundle defining a bore, wherein each of the plurality of hollow fibers includes a lumen; a first manifold attached to a first end of the plurality of hollow fibers and a second manifold attached to a second end of the plurality of hollow fibers; a fluid inlet port disposed on the first manifold and in fluid communication with a first interior volume thereof, and a fluid outlet port disposed on the second manifold and in fluid communication with a second interior volume thereof, wherein a fluid path is defined through the inlet port, the first interior volume, the lumens of the plurality of hollow fibers, the second interior volume, and the outlet port; and an impeller operable to drive fluid flow over exterior surfaces of the plurality of hollow fibers.

An electrochemical separation device includes a first electrode, a second electrode, a cell stack including alternating depleting compartments and concentrating compartments disposed between the first electrode and the second electrode, an inlet manifold configured to introduce a fluid to one of the depleting compartments or the concentrating compartments an outlet manifold, and one or more of a fluid flow director disposed within the inlet manifold and having a surface configured to alter a flow path of the fluid introduced into the inlet manifold and direct the fluid into the one of the depleting compartments or the concentrating compartments, and a second fluid flow director disposed within the outlet manifold and having a surface configured to alter a flow path of the fluid introduced into the outlet manifold via one of the depleting compartments or the concentrating compartments.

There is disclosed a fluid distribution system for distributing fluid from a single source to a plurality of downstream receptacles. The system has a distribution manifold with a single inlet and a plurality of outlets arrayed around a circumferential outer periphery. The outlets may be directed to the different receptacles which each have their own vent filter, or each receptacle connects back to the distribution manifold for common venting.

Electrochemical treatment devices for treating water and methods of assembling the devices are provided. Disclosed masking and potting techniques allow separate feeds to be delivered to and/or collected from the depleting compartments and concentrating compartments.

A water treatment device using a hollow fiber membrane module is provided, including: a water container filled with raw water; a hollow fiber membrane module installed in the water container and provided with hollow fiber membranes therein to perform water treatment by a water pressure difference; and a raw water supplying part positioned on the water container, and configured to supply the raw water into the water container through the hollow fiber membrane module, in which the hollow fiber membrane module causes the raw water supplied from the raw water supplying part collide with the hollow fiber membrane to move the hollow fiber membrane, so that it is possible to minimize contamination of the hollow fiber membrane, minimize use of energy using electricity, and wash the hollow fiber membrane by a physical method.

A method of filtering a liquid feed is described, comprising passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers. A method of filtering a liquid feed is also described comprising passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods of the invention can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

Hemofilters for in vivo filtration of blood are disclosed. The hemofilters disclosed herein provide an optimal flow of blood through the filtration channels while maintaining a pressure gradient across the filtration channel walls to enhance filtration and minimize turbulence and stagnation of blood in the hemofilter.

Silicon carbide flat sheet filtration membranes are supported on one piece manifold/end cap structures. Ends of a large number of the parallel flat plate membranes are fitted into elongated end cap slots that are part of a single molded manifold/end cap structure, such a structure being at each end of the series of membranes. In addition, a one piece external frame module can be provided to receive the gang of flat plate membranes with attached manifold/end caps. In the event of a damaged plate, the plate can be removed and replaced along with a special end cap repair section. This provides advantages over prior arrangements with individual end caps for each module or potting of the flat plates into a box or chamber.

The present disclosure relates to a diffusion device, such as a blood oxygenator or gas exchanger, having improved flow characteristics.