The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.

Chromatography method in which a gaseous, liquid or supercritical mobile phase containing species to be separated is circulated through a packing, said packing being characterized in that: —it comprises a plurality of capillary ducts extending in the packing between an upstream face through which the mobile phase enters the packing and a downstream face through which the mobile phase leaves the packing—the material of the walls comprises a first population of connected pores, providing passages from one duct to the next enabling molecular diffusion to take place between adjacent ducts, pores having a mean diameter (d.sub.pore) of greater than 2 times the molecular diameter of at least one species to be separated—the diameter of the ducts is less than 50 μm.

Chromatography method in which a gaseous, liquid or supercritical mobile phase containing species to be separated is circulated through a packing, said packing being characterized in that: —it comprises a plurality of capillary ducts extending in the packing between an upstream face through which the mobile phase enters the packing and a downstream face through which the mobile phase leaves the packing—the material of the walls comprises a first population of connected pores, providing passages from one duct to the next enabling molecular diffusion to take place between adjacent ducts, pores having a mean diameter (d.sub.pore) of greater than 2 times the molecular diameter of at least one species to be separated—the diameter of the ducts is less than 50 μm.

Disclosed are composite materials and methods of making them. The composite materials comprise a support member and a cross-linked gel, wherein the cross-linked gel is a polymer synthesized by thiol-ene or thiol-yne polymerization and cross-linking. The cross-linked gel may be functionalized by a thiol-ene or thiol-yne grafting reaction, either simultaneously with the polymerization or as the second step in a two-step procedure. The composite materials are useful as chromatographic separation media.

Disclosed are composite materials and methods of making them. The composite materials comprise a support member and a cross-linked gel, wherein the cross-linked gel is a polymer synthesized by thiol-ene or thiol-yne polymerization and cross-linking. The cross-linked gel may be functionalized by a thiol-ene or thiol-yne grafting reaction, either simultaneously with the polymerization or as the second step in a two-step procedure. The composite materials are useful as chromatographic separation media.

The invention discloses method for manufacturing agar or agarose beads, comprising the steps of: a) providing a water phase comprising an aqueous solution of agar or agarose at a temperature of 40-100° C.: b) providing an oil phase comprising a water-immiscible solvent and an emulsifier at a temperature of 40-100° C.; c) emulsifying the water phase in the oil phase to form a water-in-oil emulsion: d) cooling the water-in-oil emulsion to a temperature below a gelation temperature of the agar or agarose to form a dispersion of solidified agar or agarose beads: and c) recovering agar or agarose beads from dispersion, wherein the emulsifier comprises a phosphate ester of an alkoxy lated fatty alcohol.

The invention discloses method for manufacturing agar or agarose beads, comprising the steps of: a) providing a water phase comprising an aqueous solution of agar or agarose at a temperature of 40-100° C.: b) providing an oil phase comprising a water-immiscible solvent and an emulsifier at a temperature of 40-100° C.; c) emulsifying the water phase in the oil phase to form a water-in-oil emulsion: d) cooling the water-in-oil emulsion to a temperature below a gelation temperature of the agar or agarose to form a dispersion of solidified agar or agarose beads: and c) recovering agar or agarose beads from dispersion, wherein the emulsifier comprises a phosphate ester of an alkoxy lated fatty alcohol.

A manually actuated chromatography device comprising a chamber for receiving a liquid sample, a pump with a metering valve, and a chromatography element, wherein the pump moves a predetermined volume of liquid from the sample chamber to the chromatography element.

Method for preparing a natural organic macromolecular water treatment agent including: dissolving amylose corn starch in an alkali solution, stirring for 30 min, to obtain a suspension, freezing the suspension to fully frozen state, melting and dialyzing, to obtain a corn starch dispersion; mixing a modified flax fiber, the dispersion, nano-hybrid silica and distilled water, performing 800 W ultrasonication for 10 min, to obtain a treated suspension; taking an amount of a superabsorbent macromolecular resin with a certain shape, making it absorb water and swell into a solid hydrogel with the certain shape; mixing the solid hydrogel and the treated suspension, static defoaming, loading into a mold and solidifying, drying until the solid hydrogel is completely dehydrated, to obtain a hollow agent; spraying a catalytic degrading agent/toxin degrading agent on the surface of the hollow agent and/or the inner wall of holes thereof, to obtain the target agent.

Method for preparing a natural organic macromolecular water treatment agent including: dissolving amylose corn starch in an alkali solution, stirring for 30 min, to obtain a suspension, freezing the suspension to fully frozen state, melting and dialyzing, to obtain a corn starch dispersion; mixing a modified flax fiber, the dispersion, nano-hybrid silica and distilled water, performing 800 W ultrasonication for 10 min, to obtain a treated suspension; taking an amount of a superabsorbent macromolecular resin with a certain shape, making it absorb water and swell into a solid hydrogel with the certain shape; mixing the solid hydrogel and the treated suspension, static defoaming, loading into a mold and solidifying, drying until the solid hydrogel is completely dehydrated, to obtain a hollow agent; spraying a catalytic degrading agent/toxin degrading agent on the surface of the hollow agent and/or the inner wall of holes thereof, to obtain the target agent.