A slide output module for an automated treatment apparatus for treating tissue samples disposed on slides, the slide output module comprising: a slide output tray assembly comprising a slide output tray adjacent to a slide output cover forming one or more voids between the slide output tray and the slide output tray cover for receiving slides therein, wherein the slide output tray cover comprises a first side with a fluid inlet in communication one of the voids, and a second side configured to form a hydration chamber with a slide in said one of the voids to maintain hydration of the slide with fluid received from the fluid inlet for a designated time following treatment of the slide by the automated staining apparatus.

A microbial sample collection apparatus includes a double-sided attachment member having opposed attachment surfaces such as adhesive surfaces. A sampling member adheres to one of the opposed surfaces of the double-sided attachment member. A remaining surface of the double-sided attachment member is attachable to a face covering, i.e. face mask, of a test subject. A sample collector adheres the sampling member to a selected location on a face mask interior surface via the double-sided adhesive attachment therebetween. In this manner, microbial samples are cumulatively collected from the exhalation breath path of the test subject wearing the face mask.

The present technology provides for a microfluidic substrate configured to carry out PCR on a number of polynucleotide-containing samples in parallel. The substrate can be a single-layer substrate in a microfluidic cartridge. Also provided are a method of making a microfluidic cartridge comprising such a substrate. Still further disclosed are a microfluidic valve suitable for use in isolating a PCR chamber in a microfluidic substrate, and a method of making such a valve.

A device for sealing a reagent container storing and providing liquids, in particular in an analyzer system. The invention also relates to a reagent container using such device for sealing, a cartridge for holding such reagent container, and a method for removing a liquid from such reagent container. The instant invention provides a device for sealing a reagent container comprising an annular member configured to be inserted into the reagent container, wherein the annular member is configured to being movably coupled to the reagent container relative to its longitudinal center axis; an opening passing from a top end of the annular member to a bottom end of the annular member; and a sealing element arranged between the top end and the bottom end of the annular member for sealing the opening.

Multi-stage sample-recovery systems, including automated 2-stage and 3-stage sample-recovery systems, are provided. Such systems enable the rapid screening and recovery of samples, including viable cell-based samples, from high-throughput screening systems, including systems utilizing large-scale arrays of microcapillaries. In specific screening systems, each microcapillary comprises a solution containing a variant protein, an immobilized target molecule, and a reporter element. Immobilized target molecules may include any molecule of interest, including proteins, nucleic acids, carbohydrates, and other biomolecules. The association of a variant protein with a molecular target is assessed by measuring a signal from the reporter element. The contents of microcapillaries identified in the assays as containing variant proteins of interest can be identified and recovered using the multi-stage systems disclosed herein.

The present disclosure is directed to a microwell array comprising a plurality of wells of micro-size dimensions created on porous materials. The device can be used in various cell and tissue analytical activities, and can be formed using an etching, laminating or imprinting processes.

A method for treating a solution including nucleic acid, comprising the steps of: arranging the solution on a first surface of a first base material having the first surface, which has a well defined by an electrode and a resist; and after arranging the solution on the first surface of the first base material, pressing the first base material and a second base material, which has a hydrophobic second surface, together so that the second surface of the second base material and the first surface of the first base material face each other.

There is provided an accommodation case (1) having a first wall part (33) in which a power supply unit (40) that transmits electric power to a power supply destination in a noncontact state is provided, a second wall part (34) in which a power reception unit (50) that receives electric power that is supplied from a power supply source in a noncontact state is provided, where the second wall part (34) faces the first wall part (33), and an accommodation space (35) that is surrounded by a plurality of wall parts including the first wall part (33) and the second wall part (34).

The microfluidic device of the present invention includes a plate having a first main surface that has an opening area in which a plurality of openings for injecting fluid are formed, a second main surface being the opposite side of the first main surface, and an outer side surface communicating the first main surface and the second main surface; and a reservoir that has an opening with a bottom and is capable of storing liquid, the opening standing above the first main surface outside the opening area.

A method is provided comprising loading shells into shell retention chambers of a shell management module, the shells including corresponding reservoirs configured to hold individual quantities of liquid, the shell retention chambers arranged in a predetermined pattern on a platform of the shell management module. The method further comprises orienting discharge ends of the shells along an actuation direction within the shell retention chambers, and covering the discharge ends with closure lids to seal bottoms of the corresponding reservoirs.