An anti-fouling implantable material and a method of making the anti-fouling implantable material are disclosed. The anti-fouling implantable material includes a polymeric reinforcement layer, an intermediate layer comprising a protective polymer membrane, and an outer layer comprising an ionic polymer. The anti-fouling implantable material may have chemical and/or physical properties compatible with body tissue properties. The anti-fouling implantable material may be used for implantable medical devices, such as prosthetic heart valves and vascular grafts, among others.

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

The invention provides a synthetic gingival patch graft having a porous polymeric structure and uses thereof in the C method of treatment of periodontal diseases, conditions and symptoms.

A self-expanding wire frame for a pre-configured compressible transcatheter prosthetic cardiovascular valve, a combined inner frame/outer frame support structure for a prosthetic valve, and methods for deploying such a valve for treatment of a patient in need thereof, are disclosed.

A tissue graft product comprising two or more layers of material wherein each layer comprises extracellular matrix (ECM) or polymeric material and wherein the layers are laminated together by interlocking portions of one layer with portions of another layer.

A tissue graft product comprising two or more layers of material wherein each layer comprises extracellular matrix (ECM) or polymeric material and wherein the layers are laminated together by interlocking portions of one layer with portions of another layer.

A medical wound healing accelerator having a body that is removably attached on a fixing pin, of an external fixator for fractures, that is insertable into a bone through skin is provided. The device can further include a plurality of light source units arranged on one surface of the body to emit light and provide a beneficial effect to the wound, and a controller electrically connected to the light source units. An osteomyelitis treatment device having an insert that is insertable into an osteomyelitis part in a human body, and a plurality of light-emitting members provided to the insert to emit light is also provided. The plurality of light-emitting members can be spaced apart from each other, and a part of the insert can be cut or bent to correspond to the shape of the osteomyelitis part.

A medical wound healing accelerator having a body that is removably attached on a fixing pin, of an external fixator for fractures, that is insertable into a bone through skin is provided. The device can further include a plurality of light source units arranged on one surface of the body to emit light and provide a beneficial effect to the wound, and a controller electrically connected to the light source units. An osteomyelitis treatment device having an insert that is insertable into an osteomyelitis part in a human body, and a plurality of light-emitting members provided to the insert to emit light is also provided. The plurality of light-emitting members can be spaced apart from each other, and a part of the insert can be cut or bent to correspond to the shape of the osteomyelitis part.

The present invention relates in part to hybrid hydrogel scaffolds including a decellularized extracellular matrix (dECM) tissue, and a synthetic polymer. The dECM may include any suitable tissue including for example, lung tissue, heart tissue, heart-lung block tissue, skin tissue, liver tissue, pancreatic tissue, kidney tissue, and the like.