It is disclosed a biocomposite of hydroxyapatite on graphene oxide sheets and its use for bone tissue engineering applications, such as bone repair, bone augmentation, as well as coating of biomedical implants. Processes for preparing said biocomposites are also described.

A synthetic bead is for implantation within the body of an animal or human body. The bead includes a surface defining a shape having a bulk volume of the bead. The surface of the bead is coated with at least a first therapeutic agent to form an inner layer; and an outer layer includes a biodegradable polymer and a second therapeutic agent positioned above the inner layer.

A method for preparing a PBAT laminated membrane composite material uses PBAT or a material with PBAT as the main component and other biodegradable plastic or superfine calcium carbonate in a mixture. The temperature of the mixture is increased by means of a lamination machine segment by segment, the material is heated slowly to a molten state, and the temperature of a rolling shaft is controlled by introducing cold water to the rolling shaft when the lamination machine conducts membrane lamination, so that the temperatures of rolling wheels and the laminated membrane are controlled.

Provided are novel compounds and uses thereof in preventing antifouling by unicellular organisms and in attracting cells from multicellular organisms.

The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The orthopedic implant also includes a porous coating secured to an exterior surface of the elongated member. The porous coating includes magnesium phosphate.

A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.

Nitric oxide-releasing materials, methods of making nitric oxide-releasing materials, and uses of nitric oxide-releasing materials are provided. The nitric oxide-releasing materials include a mesoporous silica core and an outer surface having a plurality of nitric oxide donors. In an exemplary aspects, the nitric oxide-releasing material includes a mesoporous diatomaceous earth core, and an outer surface having a plurality of S-nitroso-N-acetyl-penicillamine groups covalently attached thereto. Uses of the nitric oxide-releasing materials can include coatings for medical devices such as catheters, grafts, and stents; wound gauzes; acne medications; and antiseptic mouthwashes; among others.

A coating film is provided in a cable, a medical hollow tube, a molded article and a hollow tube. The coating film is formed from a rubber composition including a rubber component and fine particles. A static friction coefficient on a surface of the coating film is 0.5 or less. When the coating film is subjected to a testing such that a long fiber non-woven fabric including cotton linters including an alcohol for disinfection with a length of 50 mm along a wiping direction is brought contiguous to the surface of the coating film at a shearing stress of 210.sup.3 MPa to 410.sup.3 MPa, followed by wiping off the surface of the coating film at a speed of 80 times/min to 120 times/min and 20,000 repetitions thereof for a wiping direction length of 150 mm, a difference (an absolute value of a difference) between the static friction coefficients of the coating film before and after the testing is not greater than 0.1.

A staple cartridge comprising staples that are lubricated before they are loaded into the staple cartridge and after they have been loaded into the staple cartridge is disclosed.

Borate-glass biomaterials comprising: aNa.sub.2O. bCaO. cP.sub.2O.sub.5. dB.sub.2O.sub.3 wherein a is from about 1-40 wt %, b is from about 10-40 wt %, c is from about 1-40 wt %, and d is from about 35-80 wt %; and wherein the biomaterial has a surface area per mass of more than about 5 m.sup.2/g. Methods of making and uses of these biomaterials.