A device for treating a skin lesion including a container, an applicator tube and an applicator tip, wherein the applicator tube is attached to the container and applicator tip to allow the passage of a skin lesion treatment agent from the container to the applicator tip.

Briefly summarized, embodiments disclosed herein are directed to apparatus and methods for removing an occlusion from an indwelling catheter. The system can include a pressurized fluid conduit for delivering pressurized fluid to an occlusion site, and ablating the occlusion. A negative pressure source in fluid communication with the catheter lumen can then aspirate the occlusion. The positive pressure source can provide a pulsed pressurized fluid to facilitate ablation. The system can also include tip tracking and tip location systems to ensure the pressurized fluid conduit does not extend beyond the catheter lumen, causing damage to the vasculature. The system can further include an ultrasound transducer, coupled with one of the catheter and the pressurized fluid conduit to provide ultrasonic wave energy to the occlusion to further facilitate ablation thereof.

A rectal injection device configured to inject a liquid into the tissues around the internal anal sphincter of a rectum. The rectal injection device comprises: i) an elongated tube having a distal end and a proximal end; ii) a rounded head coupled to the distal end of the elongated tube; iii) a needle extending from the proximal end of the elongated tube into the rounded head, wherein a tip of the needle is aligned with a hole in the rounded head; and iv) an actuator mechanism configured to move the needle to a deployed position in which the tip of the needle extends through the hole and into the anal tissues and to move the needle to a retracted position in which the tip of the needle is withdrawn within the rounded head.

A nosepiece for delivering substance to a nasal cavity of a subject, the nosepiece comprising a body part which comprises a base portion which defines a flow passage therethrough, and a projection at a distal end of the base portion which at least in part provides a tip of the nosepiece and confers a rigidity in the sagittal direction, which enables the tip to open fleshy tissue at an upper region of the nasal valve and thereby expand an open area of the nasal valve, and a flexibility in a lateral direction, orthogonal to the sagittal plane, which facilitates insertion of the tip into the nasal valve.

A piercing part for a medical infusion system includes a piercing mandrel through which at least one channel extends and which has a mandrel tip whose first jacket surface part is tapered, relative to a central longitudinal axis, towards a front end. An opposite second jacket surface part has an inclined cutting face interrupted towards the front end. The piercing part can be used for medical transfusion and infusion appliances.

Embodiments of the present invention provide a non-invasive transportation method which relates to the field of transdermal transportation and is aimed at improving absorption of active ingredients by skin. The non-invasive transportation method includes: applying needlelike crystals onto the skin, and forming a micro-channel array in epidermis by the needlelike crystals. The present invention is applicable to the transdermal transportation of active ingredients, and more commonly used in cosmetology processes.

A nebulizer capable of connecting with a mouthpiece is provided. The nebulizer includes a container, a nebulizing part, a first tube and a second tube. The container is configured to accommodate a liquid. The nebulizing part includes a chamber and a nebulizing element communicating with the container and nebulizing the liquid in the chamber. The first tube connected with the nebulizing part includes a first channel communicating with the chamber and introducing an outside airflow. The second tube is connected with the nebulizing part and the mouthpiece. A second channel of the second tube communicates with the chamber and the mouthpiece. The second tube has an expanding part at a junction of the second channel and the chamber.

Diffusion and infusion resistant implantable devices and methods for reducing pulsatile pressure are provided. The implantable device includes a balloon implantable within a blood vessel of a patient, e.g., the pulmonary artery. The balloon is injected with a fluid mixture comprising a constituent fluid(s) and a diffusion-resistant gas to provide optimal balloon volume and limit fluid diffusion throughout multiple cardiac cycles. The fluid mixture may be pressurized such that the balloon is transitionable between an expanded state and a collapsed state responsive to pressure fluctuations in the blood vessel.

An aroma/skincare therapy and phototherapy device includes: a set of fluid reservoir units; a power source; a main control unit; a low-level light therapy (LLLT) unit; plus a communication unit and/or a user-operating unit. The main control unit is coupled to the power source and the LLLT unit. Each fluid reservoir unit includes a fluid vaporizing element coupled to the main control unit and/or the user-operating unit. The main control unit obtains a set of control signals, and can selectively activate one or more fluid vaporizing elements (providing vapor based facial therapy) and/or the LLLT unit (providing phototherapy) in accordance with the set of control signals. Upper skin surface(s) can be exposed to vapor based facial therapy, and deeper/deepest layers can be exposed to phototherapy. The aroma/skincare therapy and phototherapy device provides synergistic dual aroma/skincare vapor and phototherapy treatment, which can greatly increase skincare therapy flexibility and efficacy.

A method for application of laser energy to skin including applying a first pass of laser energy from a laser system to skin, placing a layer on the skin, and applying a second pass of laser energy from the laser system that impinges on the layer to create a shockwave on the skin.