Disclosed are composite filaments for 3D printing. The filaments typically have high strength, an appropriate resorption rate, and high biocompatibility. The filaments generally contain a matrix formed of a blend containing a bioresorbable polymer and an inorganic component. The filaments can be used to produce customized scaffolds for repairing bone defects following implantation in the site of the defect. The shape and size of the scaffold can be configured to fit in and conform to the bone defect. The scaffolds are especially useful in repairing critical sized bone defect, such as a critical sized bone defect in a weight-bearing long bone.

Improved breast prostheses, methods of making breast prostheses, and methods of treatment using such breast prostheses are described.

Materials and methods for cell-mimetics having mechanical properties of biological neural axons are provided. A cell-mimetic device includes an array of fibers comprised of hexanediol diacrylate (HDDA) or an HDDA derivative, and at least one derivative of polyethylene glycol (PEG) selected from the group consisting of: PEG-acrylate, PEG-diacrylate, and any multi-arm PEG-acrylate.

Multi-layered articles or products comprising layers of filled polymer compositions, methods of making and applications or uses thereof.

A prosthesis cosmetic element comprising a main part made of a foam material and a cavity formed in the main part for receiving a prosthesis component, wherein the main part has an outer face facing away from the prosthesis component and an inner face which delimits the cavity, and a textile is secured to the inner face.

An orthodontic appliance may include an outer shell having a plurality of cavities shaped to receive the patient's teeth and generate one or more of a force or a torque in response to the appliance being worn on the patient's teeth. The orthodontic appliance may also include an inner structure having a stiffness different than a stiffness of the outer shell. The inner structure can be positioned on an inner surface of the outer shell in order to distribute the one or more of a force or a torque to at least one tooth received within the plurality of cavities.

The invention relates to a method for producing a component (9) by means of stereolithography, having the steps of: A) generating a component (9) in accordance with a virtual 3D model of the component (9) by curing a liquid plastic (7) using stereolithography, and B) cleaning the component (9) through at least one rotational movement of the component (9) about an axis of rotation or about multiple axes of rotation, wherein residues of the liquid plastic (7) are removed from the surface of the component (9) by a centrifugal force resulting from the rotational movement. The invention also relates to a 3D printing system for implementing such a method.

Compositions-of-matter comprising a matrix made of one or more, preferably two or more elastic layers and one or more viscoelastic layer are disclosed. The compositions-of-matter are characterized by high water-impermeability and optionally by self-recovery. Processes of preparing the compositions-of-matter and uses thereof as tissue substitutes or for repairing damaged tissues are also disclosed.

A prosthetic device can be implanted in the corpora cavernosa of a penis with erectile dysfunction. The device being formed by two cylinders that can be inflated with a fluid. The device comprises a variable-length erectable portion formed by a chamber that can be pressurized with a low volume of fluid and is formed between an expandable membrane and an axially extendable and foldable longitudinal rib. The membrane and rib extend between a distal tip element and an intermediate connector from which a shortenable anchoring rod emerges, the rib being a single piece formed by a variable-length distal section, an intermediate section that is foldable and extendable in an axial direction, and a proximal section comprising optimized means for the continuous lateral supply of the fluid to the pressurisable chamber. The device also has an integrated unit for storing and pressurizing the fluid, which can be implanted in the scrotum.

The present invention relates to biomaterial in the form of dispersion of cellulose nanofibrils with extraordinary shear thinning properties which can be converted into desire 3D shape using 3D Bioprinting technology. In this invention cellulose nanofibril dispersion, is processed through different mechanical, enzymatic and chemical steps to yield dispersion with desired morphological and rheological properties to be used as bioink in 3D Bioprinter. The processes are followed by purification, adjusting of osmolarity of the material and sterilization to yield biomaterial which has cytocompatibility and can be combined with living cells. Cellulose nanofibrils can be produced by microbial process but can also be isolated from plant secondary or primary cell wall, animals such as tunicates, algae and fungi. The present invention describes applications of this novel cellulose nanofibrillar bioink for 3D Bioprinting of tissue and organs with desired architecture.